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CellFreeImplant SIGNED

Cell-free Ti-based Medical Implants due to Laser-induced Microstructures

Total Cost €

EC-Contrib. €

Partnership

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CellFreeImplant project word cloud

Explore the words cloud of the CellFreeImplant project. It provides you a very rough idea of what is the project "CellFreeImplant" about.

microstructures sharp self fet market complete cell framework too water suppression cardio laser cones substrates cells subsequently body surfaces segments completely ongoing vascular removed instance flat strategic grow significantly successfully lowered spikes coverage fibroblasts medical electrochemically pacemakers linabiofluid identification miniaturized diseases implants ti smart overgrown fluids ablation wetting incomplete demonstrated sapphire months more irradiation morphology little created femtosecond regarding action cellfreeimplant surface alloy patients time structures density casing new pulsed spread consisting

Project "CellFreeImplant" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITAT LINZ Organization address address: ALTENBERGER STRASSE 69 city: LINZ postcode: 4040 website: www.jku.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Austria [AT]
Total cost	100˙000 €
EC max contribution	100˙000 € (100%)
Programme	1. H2020-EU.1.2.1. (FET Open)
Code Call	H2020-FETOPEN-4-2016-2017
Funding Scheme	CSA
Starting year	2018
Duration (year-month-day)	from 2018-07-01 to 2019-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITAT LINZ UNIVERSITAT LINZ Organization address address: ALTENBERGER STRASSE 69 city: LINZ postcode: 4040 website: www.jku.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (LINZ)	coordinator	50˙000.00
2	BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG Organization address address: Unter den Eichen 87 city: BERLIN postcode: 12205 website: www.bam.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERLIN)	participant	35˙000.00
3	KEPLER UNIVERSITATSKLINIKUM GMBH KEPLER UNIVERSITATSKLINIKUM GMBH Organization address address: KRANKENHAUSSTRASSE 7A city: LINZ postcode: 4020 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (LINZ)	participant	15˙000.00

Map

Project objective

New miniaturized and smart medical implants are more and more used in all medical fields, including miniaturized pacemakers. These implants with a casing consisting often of a Ti-alloy may have to be removed after some months or several years and shall therefore not be completely overgrown by the cells. In the framework of the ongoing FET Open project LiNaBioFluid, we successfully demonstrated that self-organized sharp cones or spikes at Ti-alloy substrates created by pulsed laser-ablation can result not only in complete wetting by water and body fluids but at the same time provide too little surface for the cells (i.e., fibroblasts) to grow on. Compared to flat surfaces, the cell density on the microstructures is significantly lowered, the coverage is incomplete and the cells have a clearly different morphology. The best results regarding suppression of cell growth are obtained on structures created by femtosecond Ti:sapphire laser irradiation, which are subsequently electrochemically treated. The goal of the Coordination and Support Action CellFreeImplant is to find strategic partners (end-users) for future development of smart medical implants addressing wide-spread patients needs for instance in the field of cardio-vascular diseases. The project activities include the identification of the market segments and needs and assessment of the technology with end-users.

Publications

List of publications.
year	authors and title	journal	last update
2019	L. Caldero Surface Functionalization with LIPSS Continues to Expand into New Industries published pages: 9 -11, ISSN: , DOI:	LIA TODAY Newsletter 27/4 (July/August 2019)	2020-02-20
2018	P. Fosodeder, M. Muck, W. Baumgartner, A. Weth, C. Steinwender, A.W. Hassel, J. Heitz Laser-Structured and Anodized Ring around Ti Cylinders as barrier against Overgrowth by Fibroblasts published pages: II - III, ISSN: , DOI:	Journal fÃ¼r Kardiologie - Austrian Journal of Cardiology 25 (11â€“12_online)	2019-06-27

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The information about "CELLFREEIMPLANT" are provided by the European Opendata Portal: CORDIS opendata.