Opendata, web and dolomites

DYCOCIRC SIGNED

Basal ganglia circuit mechanisms underlying dynamic cognitive behavior

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 DYCOCIRC project word cloud

Explore the words cloud of the DYCOCIRC project. It provides you a very rough idea of what is the project "DYCOCIRC" about.

unlock    neural    onto    decision    implicitly    toward    multiple    experiments    re    stages    mice    population    basal    cell    kinds    actions    circuit    demonstrated    nature    journey    function    free    dynamics    exert    events    either    correlate    satisfying    uniquely    dopamine    fruitful    implicated    choosing    image    judge    frontal    types    dopaminergic    cognition    input    signals    themselves    choices    immediacy    mysteries    time    circuits    promise    reward    safer    elapsed    weigh    ganglia    bg    mechanisms    inputs    dissect    populations    bases    behavior    neuromodulatory    laboratory    dynamic    cortico    neurons    rats    broadly    representation    relate    learning    generate    critical    animals    people    difficult    faced    da    mapping    poised    computational    recording    striatal    transformed    previously    do    neuron    regarding    moment    judgments    explicitly    brain    planning    deep    manipulate    internal    existence    relationship    understand   

Project "DYCOCIRC" data sheet

The following table provides information about the project.

Coordinator
FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD 

Organization address
address: AVENIDA BRASILIA, CENTRO DE INVESTIGACAO DA FUNDACAO CHAMPALIMAUD
city: LISBOA
postcode: 1400-038
website: http://fchampalimaud.org/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Total cost 2˙000˙000 €
 EC max contribution 2˙000˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-COG
 Funding Scheme ERC-COG
 Starting year 2018
 Duration (year-month-day) from 2018-04-01   to  2023-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD PT (LISBOA) coordinator 2˙000˙000.00

Map

 Project objective

You’re faced with a difficult choice. What do you do? Most people will, either explicitly or implicitly, weigh the possible consequences their decision. This involves an internal journey through possible events. Its these kinds of dynamic processes and their mapping onto behavior that characterize higher brain function. And yet, their very internal nature is both what makes them of critical interest and so difficult to study. Here, we propose to study a simple, well-controlled decision-making behavior wherein mice have to generate a dynamic, internal representation of elapsed time in order to make choices that result in reward. We focus on frontal cortico-basal ganglia circuits and their dopaminergic inputs that together are broadly implicated in cognition and involved in the production of this particular behavior. We have demonstrated previously that striatal population dynamics and dopamine neuron activity both correlate with and exert control over animals’ judgments. Having identified key signals at multiple stages of the BG circuit related to this decision in rats and mice, my laboratory is now uniquely poised to dissect the circuit mechanisms by which such signals are generated and transformed into actions. Specifically, we will 1) Measure activity of specific cell types at multiple stages of the BG as mice judge duration. 2) Image and manipulate the activity of DA neurons while recording from neural populations in the BG to determine the relationship between neuromodulatory input, neural dynamics, and behavior. 3) Relate the activity of cortico-striatal inputs to striatal responses during behavior to understand the computational and circuit bases of striatal activity. These experiments promise to unlock deep mysteries regarding how animals free themselves from the immediacy of the current moment, learning, planning, and choosing their path toward a safer, more fruitful, and satisfying existence.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "DYCOCIRC" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "DYCOCIRC" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

E-DIRECT (2020)

Evolution of Direct Reciprocity in Complex Environments

Read More  

REPLAY_DMN (2019)

A theory of global memory systems

Read More  

HYDROGEN (2019)

HighlY performing proton exchange membrane water electrolysers with reinforceD membRanes fOr efficient hydrogen GENeration

Read More