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BactoBubble SIGNED

Microscale investigation of key bacterial phenotypes enhancing collection by rising bubbles and aerial dispersal

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 BactoBubble project word cloud

Explore the words cloud of the BactoBubble project. It provides you a very rough idea of what is the project "BactoBubble" about.

burst    inert    largely    aerosols    apart    microscopic    bacteria    collection    fundamental    h2    characterization    flow    career    internationally    varying    builds    modify    containing    drive    enhanced    atmospheric    dispersal    nutrient    environmental    experiments    modeling    phenomena    originates    size    innovative    microscopy    societal    eject    hypotheses    microfluidic    training    interactions    bubble    microscale    aerial    starvation    independent    bubbles    transport    alter    interfaces    impacts    recognised    certain    h1    microdroplets    model    starkly    group    enrichment    thereby    rising    interaction    scientific    rates    marine    spreading    springboard    motility    complemented    domain    linking    microbial    multidisciplinary    encounter    predictive    channel    mutants    particles    pinned    poor    combining    observation    vary    bacterial    underlies    levels    mathematical    ecology    little    cell    ocean    quantify    optical    aerosolisation    cells    changing    first    species    microbes    global    disease    surface    starving    microfluidics   

Project "BactoBubble" data sheet

The following table provides information about the project.

Coordinator
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH 

Organization address
address: Raemistrasse 101
city: ZUERICH
postcode: 8092
website: https://www.ethz.ch/de.html

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 175˙419 €
 EC max contribution 175˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-06-01   to  2020-11-17

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) coordinator 175˙419.00

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 Project objective

Aerial transport of microbes has fundamental consequences for microbial dispersal, disease spreading, and atmospheric phenomena. In the ocean, aerosolisation largely originates from collection of bacteria by rising bubbles, which burst at the surface and eject cells in microdroplets. This process underlies the enrichment of bacteria in aerosols. While we know that collection rates vary among bacterial species, we know little about the bacterial properties promoting collection, and even less about which factors drive enhanced collection of certain species. Combining state-of-the-art microfluidics and microscopy, I will provide the first microscopic observation of bubble-bacteria interaction, to investigate two hypotheses: H1: Cell motility increases microbial collection by rising bubbles. Motility sets bacteria starkly apart from inert particles, likely promoting collection by increasing encounter rates and changing surface properties. H2: Starvation increases microbial collection by rising bubbles. Starving bacteria modify their surface and size, which may enhance collection by bubbles, thereby promoting dispersal from nutrient poor areas. To investigate H1 and H2, I will develop a novel microfluidic flow channel containing a pinned bubble, and use advanced optical microscopy to quantify collection rates for a range of bacteria. Experiments using mutants to alter motility (H1) and varying starvation levels (H2) will be complemented by characterization of bacterial surface properties. I will also develop the first mathematical model predictive for microbial aerosolisation. This project builds on my experience in modeling and interfaces, enhanced by training in microfluidics and marine microbial ecology within an internationally recognised multidisciplinary group, in order to open an innovative domain linking microscale interactions with global-scale scientific, environmental and societal impacts, and provide a springboard towards an independent research career.

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