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AMR-TB SIGNED

Theoretical and computational investigation of tuberculosis antimicrobial resistance development based on extensive experimental library of mycobacterium strains

Total Cost €

EC-Contrib. €

Partnership

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AMR-TB project word cloud

Explore the words cloud of the AMR-TB project. It provides you a very rough idea of what is the project "AMR-TB" about.

mathematicians diseases expertise building utilise biochemists devoted biologists health bacteria bacterial world declared pressing threat tightly groups computational catalase treatment responsible clinicians suggesting serious computer laboratories strains global multiple resistant tb resistance isoniazid training leads interconnected engineers drug library generation death mechanisms spectrum basis solving researcher forming experimental young physicists antimicrobial models mycobacterium theoretical model organization overcoming multidrug mutated amr tuberculosis specialised interacts researches molecular

Project "AMR-TB" data sheet

The following table provides information about the project.

Coordinator	ASTON UNIVERSITY Organization address address: ASTON TRIANGLE city: BIRMINGHAM postcode: B4 7ET website: www.aston.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Total cost	731˙400 €
EC max contribution	731˙400 € (100%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2018
Funding Scheme	MSCA-RISE
Starting year	2019
Duration (year-month-day)	from 2019-02-01 to 2023-01-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ASTON UNIVERSITY ASTON UNIVERSITY Organization address address: ASTON TRIANGLE city: BIRMINGHAM postcode: B4 7ET website: www.aston.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (BIRMINGHAM)	coordinator	138˙000.00
2	INSTITUT BIOHIMII IM.O.V. PALLADINA NACIONALNOY AKADEMII NAUK UKRAINI INSTITUT BIOHIMII IM.O.V. PALLADINA NACIONALNOY AKADEMII NAUK UKRAINI Organization address address: LEONTOVICHA STREET 9 city: KYIV postcode: 1601 website: http://www.biochemistry.org.ua contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UA (KYIV)	participant	423˙200.00
3	TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV Organization address address: VOLODYMYRSKA ST 60 city: KYIV postcode: 1033 website: www.univ.kiev.ua contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UA (KYIV)	participant	87˙400.00
4	UNIVERSITA DEGLI STUDI DI MESSINA UNIVERSITA DEGLI STUDI DI MESSINA Organization address address: PIAZZA PUGLIATTI 1 city: MESSINA postcode: 98122 website: www.unime.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MESSINA)	participant	46˙000.00
5	UNIVERSITY OF SURREY UNIVERSITY OF SURREY Organization address address: Stag Hill city: GUILDFORD postcode: GU2 7XH website: www.surrey.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (GUILDFORD)	participant	27˙600.00
6	AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS Organization address address: CALLE SERRANO 117 city: MADRID postcode: 28006 website: http://www.csic.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	participant	9˙200.00
7	ESCUELA POLITECNICA NACIONAL ESCUELA POLITECNICA NACIONAL Organization address address: LADRON DE GUEVARA city: QUITO postcode: 17012759 website: http://www.epn.edu.ec contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EC (QUITO)	partner	0.00
8	FEDERAL STATE INSTITUTION SAINT PETERSBURG RESEARCH INSTITUTE OF PHTHISIOPULMONOLOGY OF THE FEDERAL AGENCY FOR HIGH TECHNOLOGY MEDICAL AID FEDERAL STATE INSTITUTION SAINT PETERSBURG RESEARCH INSTITUTE OF PHTHISIOPULMONOLOGY OF THE FEDERAL AGENCY FOR HIGH TECHNOLOGY MEDICAL AID Organization address address: LIGOVSKY PROSPEKT 2-4 city: SAINT PETERSBURG postcode: 193063 website: www.spbniif.ru contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	RU (SAINT PETERSBURG)	partner	0.00
9	KURSK STATE UNIVERSITY KURSK STATE UNIVERSITY Organization address address: RADISHCHEVA ST 33 city: KURSK postcode: 305000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	RU (KURSK)	partner	0.00
10	RIKEN THE INSTITUTE OF PHYSICAL ANDCHEMICAL RESEARCH RIKEN THE INSTITUTE OF PHYSICAL ANDCHEMICAL RESEARCH Organization address address: HIROSAWA 2-1 city: WAKO SHI SAITAMA postcode: 351 0198 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	JP (WAKO SHI SAITAMA)	partner	0.00
11	SAINT PETERSBURG STATE UNIVERSITY SAINT PETERSBURG STATE UNIVERSITY Organization address address: UNIVERSITETSKAYA NAB 7/9 city: SAINT PETERSBURG postcode: 199034 website: www.spbu.ru contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	RU (SAINT PETERSBURG)	partner	0.00

Map

Project objective

Multidrug resistance of Mycobacterium tuberculosis is declared a serious global threat by the World Health Organization. Our project aims at developing a comprehensive model of molecular mechanisms responsible for antimicrobial drug resistance of tuberculosis. Isoniazid is the main drug used for TB treatment, because it interacts with the bacterial catalase that leads to the bacterial death. The library of isoniazid resistant strains (over 100 different strains) will be used as experimental basis for building theoretical and computational models of the molecular processes leading to drug resistance of mutated bacteria. The model will be used for suggesting effective treatment targeting these mechanisms and overcoming the resistance. AMR-TB RISE will be used to utilise the expertise of highly specialised research groups of biologists, clinicians, biochemists, physicists, computer engineers, and mathematicians allowing the researches from these groups to work in multiple laboratories of the Consortium all over the world. Particular attention will be given to training the next generation of young researcher and forming tightly interconnected, long term collaboration devoted to solving the pressing global problem of antimicrobial resistance not only in TB, but in a wide spectrum of diseases.

Deliverables

List of deliverables.
Project website and project Web 2.0 presence	Other	2020-04-09 20:15:13

Take a look to the deliverables list in detail: detailed list of AMR-TB deliverables.

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The information about "AMR-TB" are provided by the European Opendata Portal: CORDIS opendata.