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PanCaVax SIGNED

Personalised Pancreatic Cancer Vaccination Therapy derived from Autologous Tumor Cells and Neoantigens

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

PanCaVax project word cloud

Explore the words cloud of the PanCaVax project. It provides you a very rough idea of what is the project "PanCaVax" about.

cytuvax pancavax driving sufficient favorable vaccines act vaccination lacking months clinical regulatory survival innovation netherlands interaction disease 12 depot inhibitor density obtain successfully platform therapy adjuvant pancreatic financial proof iiia 2012 antibodies rate october least patented vaccine patients influence cytokine extremely molecules immune locally local applies considerably motivated 90 single combinations maastricht cytokines responders life acceptable outcome enterprise efficacy approval first manner checkpoint 24 median biotech team preclinical iib treatment adjuvants ultimate expectancy limits exists systemically decided substantially vaccinated cancer mild founded complete universal curative formulated trial deadly unprecedented hepatitis

Project "PanCaVax" data sheet

The following table provides information about the project.

Coordinator	CYTUVAX BV Organization address address: OXFORDLAAN 55 city: MAASTRICHT postcode: 6229 EV website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Project website	http://www.cytuvax.com
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-SMEInst-2018-2020-1
Funding Scheme	SME-1
Starting year	2018
Duration (year-month-day)	from 2018-12-01 to 2019-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	CYTUVAX BV CYTUVAX BV Organization address address: OXFORDLAAN 55 city: MAASTRICHT postcode: 6229 EV website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	coordinator	50˙000.00

Map

Project objective

CyTuVax B.V. is a biotech enterprise founded in Maastricht (the Netherlands) in October 2012. It applies depot-formulated cytokines (interaction molecules of the immune system), which enhance immune responses in an unprecedented manner when used in extremely high local density. Single and multi-cytokine combinations can be formulated by simple procedures and act as strong adjuvants, driving immune responses to their limits. It is a universal, patented platform adjuvant technology that can be applied to any vaccines and can have great influence on future vaccine technology. CyTuVax achieved the first clinical proof of concept in a Phase I trial in which 90% of hepatitis B non-responders were successfully vaccinated. Phase II is on-going. CyTuVax decided now to focus on the challenging problem of developing a vaccine for pancreatic cancer, a deadly disease for which no curative treatment exists. Its cancer vaccination therapy (PanCaVax) should substantially improve the life-expectancy by extending the median survival rate to at least 12-24 months. Costs of PanCaVax will be considerably less compared to checkpoint inhibitor antibodies, with locally strong, but systemically mild, side effects expected. CyTuVax’ highly motivated team’s next step is to complete the preclinical development of PanCaVax. Key impact of our innovation would be that it is providing a favorable clinical outcome and sufficient proof of efficacy to obtain financial resources for next steps in Phase IIb/IIIa, regulatory approval and ultimate access to pancreatic cancer patients currently lacking an acceptable therapy.

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The information about "PANCAVAX" are provided by the European Opendata Portal: CORDIS opendata.