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PROTON SIGNED

Proton transport and proton-coupled transport

Total Cost €

0

EC-Contrib. €

0

Partnership

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 PROTON project word cloud

Explore the words cloud of the PROTON project. It provides you a very rough idea of what is the project "PROTON" about.

human    resolved    pharmacologically    drug    serve    moieties    scientific    phd    secure    technologies    settings    close    energy    cross    private    structures    chronic    industrial    gastritis    basic    channel    multidisciplinary    microscopy    fuel    interfacial    incomplete    containing    transporters    mobility    highest    proton    humanity    channels    15    layers    arrangement    responsible    mechanism    health    sectors    imaging    students    fluorescence    cancer    synthetic    confines    spectroscopy    diseases    duodenal    protein    preparing    solid    edge    relay    transfer    transferable    transporter    interfere    threats    public    biofuel    details    reactions    interdisciplinary    proteinaceous    membrane    disciplinary    substances    biomimetic    skills    harmonic    solving    molecule    curing    sustainable    unresolved    migration    molecular    employability    cutting    acquire    train    positions    competitive    calculations    societies    kinds    industry    clarifying    time    ulcers    solutions    practical    single    science    training    bioengineering    rational    generate    qualify    comprising    strategies    emphasis    reaction    obesity    water    holds    improvement    cells    transport    cavities    gastric    resolve    hampered   

Project "PROTON" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAT LINZ 

Organization address
address: ALTENBERGER STRASSE 69
city: LINZ
postcode: 4040
website: www.jku.at

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Total cost 3˙976˙976 €
 EC max contribution 3˙976˙976 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2019
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-09-01   to  2023-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAT LINZ AT (LINZ) coordinator 528˙414.00
2    UNIVERSITETET I OSLO NO (OSLO) participant 584˙684.00
3    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE CH (LAUSANNE) participant 562˙553.00
4    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 274˙802.00
5    VETERINAERMEDIZINISCHE UNIVERSITAET WIEN AT (VIENNA) participant 264˙207.00
6    THE HEBREW UNIVERSITY OF JERUSALEM IL (JERUSALEM) participant 263˙500.00
7    BOEHRINGER INGELHEIM PHARMA GMBH &CO KG DE (INGELHEIM) participant 252˙788.00
8    CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL DE (KIEL) participant 252˙788.00
9    FREIE UNIVERSITAET BERLIN DE (BERLIN) participant 252˙788.00
10    INTANA BIOSCIENCE GMBH DE (PLANEGG MARTINSRIED) participant 252˙788.00
11    UNIVERSITAT DES SAARLANDES DE (SAARBRUCKEN) participant 252˙788.00
12    USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i. CZ (PRAHA) participant 234˙871.00

Map

 Project objective

Secure, competitive, and sustainable energy production is a major challenge facing human societies. Biomimetic solutions such as the development of new biofuel cells are hampered by our thus far incomplete understanding of proton transfer reactions. The same holds for health threats to humanity: Curing diseases like cancer, obesity, chronic gastritis, gastric and duodenal ulcers, requires to pharmacologically interfere - in their molecular details - with yet unresolved proton transfer reactions. Here we aim at clarifying the molecular reaction mechanism in the confines of interfacial water layers and proteinaceous cavities with emphasis on arrangement and mobility of proton relay moieties. Achieving this requires an interdisciplinary, multi-level approach comprising cutting edge technologies like second harmonic imaging, single molecule and time resolved fluorescence microscopy and spectroscopy, advanced calculations of proton transfer, bioengineering of membrane channel and transporter containing systems, synthetic design of biomimetic proton channels, solving protein structures and rational drug design.

PROTON will train 15 PhD students, who will acquire a solid state-of-the-art multidisciplinary scientific training in all kinds of proton migration/reaction systems, covering from basic science to industrial applications, thus preparing them to generate new scientific knowledge of the highest impact. In addition, practical training on transferable skills will increase their employability and qualify them for responsible positions in private and public sectors. Cross-disciplinary strategies and close collaboration with industry will enable them to resolve the molecular details of proton driven processes in all kinds of settings - enabling the improvement of biomimetic applications – up to fuel cells - and to identify lead substances which may serve to pharmacologically interfere with proton transport through membrane channels and transporters.

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The information about "PROTON" are provided by the European Opendata Portal: CORDIS opendata.

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