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GRANROSE SIGNED

Using a blood cell-based approach to determine gluten responsiveness and to bring a novel, less invasive assay on the market to diagnose celiac disease.

Total Cost €

EC-Contrib. €

Partnership

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GRANROSE project word cloud

Explore the words cloud of the GRANROSE project. It provides you a very rough idea of what is the project "GRANROSE" about.

duodenal cd trustworthy biomarker microbiome dutch replace date transglutaminase mistake perform examination associate contribution collection antibodies training celiac market proper expensive innovation strengthen neutroscan function diagnostics position neutrophil specimens innovative screen setting assays biomarkers multidisciplinary building performing diagnostic demand serology skills career auto line embedding sme gaining human panel thereby molecular gluten serum personal diagnosis biopsy business hiring ia translational complete prone proof distinguishing granrose specimen plays diagnosed invasive tissue biotech correct hla feasibility assay elaborate disease genotypes confirm benefits

Project "GRANROSE" data sheet

The following table provides information about the project.

Coordinator	MICROBIOME LIMITED Organization address address: SIDNEY STREET 80 city: FOLKESTONE postcode: CT19 6HQ website: www.microbiome.eu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Total cost	130˙062 €
EC max contribution	130˙062 € (100%)
Programme	1. H2020-EU.2.3.2.2. (Enhancing the innovation capacity of SMEs)
Code Call	H2020-INNOSUP-2019-02
Funding Scheme	CSA
Starting year	2019
Duration (year-month-day)	from 2019-10-15 to 2020-10-14

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	MICROBIOME LIMITED MICROBIOME LIMITED Organization address address: SIDNEY STREET 80 city: FOLKESTONE postcode: CT19 6HQ website: www.microbiome.eu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (FOLKESTONE)	coordinator	130˙062.00

Map

Project objective

Microbiome is a Dutch R&D-performing SME developing molecular diagnostic assays based on human biomarkers with one of its focuses to celiac disease diagnostics. We developed a molecular diagnostic assay to screen HLA genotypes that are known to be associated with celiac disease (CD). Up to date, CD is diagnosed by serology (e.g. the presence of auto-antibodies to tissue transglutaminase 2 in the serum) and diagnosis requires further proof by analysis of a duodenal biopsy specimen. The collection of biopsy specimens requires an invasive examination and correct embedding of the tissue is essential for proper analysis of the tissue. This part of CD diagnosis is expensive, elaborate and prone to mistake. Innovation that trustworthy and efficiently can replace biopsy is in high demand. GRANROSE will enable Microbiome to strengthen its position as an innovative biotech SME, developing a novel assay, NeutroScan, for the CD market. GRANROSE will do this through hiring an Innovation Associate (IA). • The IA will confirm and complete a biomarker panel that plays a role in gluten-related neutrophil function. • The IA will develop an assay to study neutrophil function in gluten-related disease. • The IA will perform a technical feasibility study for and investigate the market potential of the NeutroScan, an assay distinguishing gluten-related disease based on neutrophil function. GRANROSE will not only bring major benefits for Microbiome, but is focused around the training of the Innovation Associate, thereby greatly improving his/her career development. • Gaining novel technical skills and building an own research line with translational diagnostic applications. • Gaining innovation and business management skills in a multidisciplinary setting. • A training program tailored to his/her specific needs and major contribution to personal career development.

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The information about "GRANROSE" are provided by the European Opendata Portal: CORDIS opendata.