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CAESAR SIGNED

Developing Therapeutic Antibodies for Pets

Total Cost €

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EC-Contrib. €

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Partnership

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 CAESAR project word cloud

Explore the words cloud of the CAESAR project. It provides you a very rough idea of what is the project "CAESAR" about.

launch    dogs    causes    3k    treat    expanding    demonstrated    cagr    sufficiently    2018    canine    chronic    veterinary    shifts    market    therapeutic    library    managed    hire    financial    founded    antibodies    pets    bowel    german    ease       emotional    global    therapy    animal    inflammation    synthetic    antibody    reliance    generating    5k    biotech    causing    severe    first    immunogenic    revenue    pet    species    human    put    worth    owners    caesar    ibd    expensive    2million    overcome    scalable    licensing    affordable    distress    ineffective    people    medical    poorly    suffering    synthesize    spend    relieve    companion    companions    400    royalties    medicine    company    pay    gt    ge    12    solution    display    therapeutics    therapies    29bn    specializing    2016    health    15m    40    adivo    animals    cancer    diseases    native    inflammatory    untenable    generate    team    demographic    phage    ownership    complete   

Project "CAESAR" data sheet

The following table provides information about the project.

Coordinator
ADIVO GMBH 

Organization address
address: AM KLOPFERSPITZ 19
city: PLANEGG
postcode: 82152
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-11-01   to  2020-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ADIVO GMBH DE (PLANEGG) coordinator 50˙000.00

Map

 Project objective

Chronic inflammatory diseases in pets such as Inflammatory Bowel Diseases (IBD) are poorly managed causing emotional and financial distress to pet owners. Current therapies are ineffective - they do not relieve pet suffering and lead to the animal being put down. Therapies are also expensive with costs up to €400/month. Antibody therapy for such conditions has long been used in human medicine but has not been sufficiently developed for veterinary medicine and causes an immunogenic response as the antibodies are not species specific. Antibodies need to be adapted which is expensive and causes severe side effects making them an untenable solution at present. Pet ownership in the EU has been on the increase (up by 2million pets since 2016) due to demographic shifts and a greater reliance on pets as companions. The global animal health market is worth > €29Bn growing at a CAGR of 6% with pet health making up 40% of the market. Pet owners spend €3k - €5k/ year on their pet’s health and are willing to pay to ease pet suffering. adivo is a German biotech company specializing in generating species-specific therapeutic antibodies for companion animals. adivo was founded in 2018. The adivo-team aims to address medical needs in dogs including cancer and chronic inflammation, with the potential of expanding activities into the development of therapeutics for other species in future. adivo has developed CAESAR, the first of a kind synthetic canine phage-display library to generate therapeutic antibodies for dogs. We have developed a complete library from which we can synthesize therapeutic antibodies native to treat IBD. Our solution will overcome the challenges of current therapies and provide an affordable, scalable solution for effective antibody therapy for pets which has been demonstrated in human medicine. We expect to generate out-licensing revenue ≥€15M when we launch the product before royalties and hire 12 people.

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The information about "CAESAR" are provided by the European Opendata Portal: CORDIS opendata.

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