EMTICS
European Multicentre Tics in Children Studies
| Coordinatore | ACADEMISCH ZIEKENHUIS GRONINGEN
Organization address
address: Hanzeplein 1 contact info |
| Nazionalità Coordinatore | Netherlands [NL] |
| Sito del progetto | http://www.emtics.eu/ |
| Totale costo | 8˙067˙587 € |
| EC contributo | 6˙000˙000 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2011-two-stage |
| Funding Scheme | CP-FP |
| Anno di inizio | 2011 |
| Periodo (anno-mese-giorno) | 2011-12-01 - 2017-05-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
ACADEMISCH ZIEKENHUIS GRONINGEN
Organization address
address: Hanzeplein 1 contact info |
NL (GRONINGEN) | coordinator | 473˙339.00 |
| 2 |
DEMOCRITUS UNIVERSITY OF THRACE
Organization address
address: PANEPISTIMIOUPOLI contact info |
EL (KOMOTINI) | participant | 746˙941.00 |
| 3 |
ISTITUTO SUPERIORE DI SANITA
Organization address
address: Viale Regina Elena 299 contact info |
IT (ROMA) | participant | 713˙967.00 |
| 4 |
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Organization address
address: GESCHWISTER SCHOLL PLATZ 1 contact info |
DE (MUENCHEN) | participant | 400˙509.00 |
| 5 | Concentris Research Management GmbH | DE | participant | 360˙000.00 |
| 6 |
TECHNISCHE UNIVERSITAET DRESDEN
Organization address
address: HELMHOLTZSTRASSE 10 contact info |
DE (DRESDEN) | participant | 303˙394.00 |
| 7 |
UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA
Organization address
address: Piazzale Aldo Moro 5 contact info |
IT (ROMA) | participant | 298˙442.00 |
| 8 |
QUEEN MARY UNIVERSITY OF LONDON
Organization address
address: 327 MILE END ROAD contact info |
UK (LONDON) | participant | 264˙928.00 |
| 9 |
UNIVERSITA DEGLI STUDI DI BARI ALDO MORO
Organization address
address: Piazza Umberto I 1 contact info |
IT (BARI) | participant | 241˙915.00 |
| 10 |
GLAXOSMITHKLINE VACCINES SRL
Organization address
address: Via Fiorentina 1 contact info |
IT (SIENA) | participant | 209˙200.00 |
| 11 |
PROIMMUNE LTD
Organization address
address: ROBERT ROBINSON AVENUE THE MAGDALEN contact info |
UK (OXFORD) | participant | 194˙760.00 |
| 12 |
GUYS AND ST THOMAS' NHS FOUNDATIONTRUST
Organization address
address: Westminster Bridge Road contact info |
UK (London) | participant | 183˙950.00 |
| 13 |
CLALIT HEALTH SERVICES
Organization address
address: ARLOZOROV STREET 101 contact info |
IL (TEL AVIV) | participant | 152˙000.00 |
| 14 |
Department of Health
Organization address
address: Quarry House, Quarry Hill contact info |
UK (Leeds) | participant | 148˙603.00 |
| 15 |
UNIVERSITY COLLEGE LONDON
Organization address
address: GOWER STREET contact info |
UK (LONDON) | participant | 144˙442.00 |
| 16 |
Advanced Practical Diagnostics
Organization address
address: Hertoginstraat 82 contact info |
BE (Turnhout) | participant | 144˙360.00 |
| 17 |
MEDIZINISCHE HOCHSCHULE HANNOVER
Organization address
address: Carl-Neuberg-Strasse 1 contact info |
DE (HANNOVER) | participant | 133˙800.00 |
| 18 |
REGION HOVEDSTADEN
Organization address
address: KONGENS VAENGE 2 contact info |
DK (HILLEROD) | participant | 121˙400.00 |
| 19 |
UNIVERSITA DEGLI STUDI DI CATANIA
Organization address
address: PIAZZA UNIVERSITA 2 contact info |
IT (CATANIA) | participant | 113˙975.00 |
| 20 |
VADASKERT ALAPITVANY A GYERMEKEK LELKI EGESZSEGEERT
Organization address
address: HUVOSVOLGYI UT 116 contact info |
HU (BUDAPEST) | participant | 111˙400.00 |
| 21 |
FUNDACIO PRIVADA CLINIC PER A LA RECERCA BIOMEDICA
Organization address
address: CARRER ROSSELLO 149-153 contact info |
ES (BARCELONA) | participant | 101˙400.00 |
| 22 |
UNIVERSITAET ZU LUEBECK
Organization address
address: RATZEBURGER ALLEE 160 contact info |
DE (LUEBECK) | participant | 89˙800.00 |
| 23 |
AZIENDA SANITARIA LOCALE BARI
Organization address
address: LUNGOMARE STARITA 6 contact info |
IT (BARI) | participant | 83˙400.00 |
| 24 |
Servicio Andaluz de Salud
Organization address
address: AVENIDA DE LA CONSTITUCION 18 contact info |
ES (SEVILLA) | participant | 75˙400.00 |
| 25 |
UNIVERSITAET ZUERICH
Organization address
address: Raemistrasse 71 contact info |
CH (ZURICH) | participant | 73˙400.00 |
| 26 |
URWYLER ADRIAN - CYTOLAB
Organization address
address: RAIRING 66 contact info |
CH (DALLIKON) | participant | 72˙000.00 |
| 27 |
Academisch Medisch Centrum bij de Universiteit van Amsterdam
Organization address
address: MEIBERGDREEF 9 contact info |
NL (AMSTERDAM) | participant | 43˙275.00 |
| 28 |
HEALTH PROTECTION AGENCY HPA
Organization address
address: Central Office - 7th Floor, Holborn Gate - High Holborn 330 contact info |
UK (LONDON) | participant | 0.00 |
| 29 |
THE UNIVERSITY OF BIRMINGHAM
Organization address
address: Edgbaston contact info |
UK (BIRMINGHAM) | participant | 0.00 |
| 30 |
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
Organization address
address: Martinistrasse 52 contact info |
DE (HAMBURG) | participant | 0.00 |
Mappa
Word cloud
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Obiettivo del progetto (Objective)
'This project will undertake pre-clinical and cohort studies that address susceptibility factors for paediatric and adolescent tic disorders, with a particular focus on comorbid obsessive-compulsive symptomatology, from clinical, epidemiological, genetic, microbiological and immunological angles. EMTICS aims to elucidate the complex aetiology of the onset and clinical course of chronic tic disorders and associated obsessive-compulsive symptoms, through disentangling the interplay between environmental factors and genetic background; translate research findings into clinical applications by developing disease prediction models and investigation of a treatment strategy; and will establish a Pan-European infrastructure for the study of tic disorders. We hypothesise that the onset and/or exacerbation of tic and comorbid obsessive-compulsive disorders is associated with increased preceding occurrence of Group A beta-haemolytic Streptococcus (GAS) infections of specific molecular subtypes, and that this association is based on genetic susceptibility factors and mediated through immunological mechanisms related to psychosocial stress and immunological factors in host and GAS strains. Large-scale cohort studies will involve affected patients and at-risk first-degree relatives within an integrated, multidisciplinary research strategy. Treatment effects of active surveillance and standardized antibiotic treatment of GAS colonisation, thus addressing one of the main environmental factors involved (GAS infections) will be evaluated. Our approach will result in the identification of genetic and environmental susceptibility factors and will greatly contribute to a better understanding of the underlying mechanisms of tic disorders, with a focus on elucidating the role of autoimmunity. Our consortium brings together the highest expertise in the field of tic disorders across Europe in academia and industry, including a number of SMEs and a professional management company.'
Introduzione (Teaser)
The EMTICS study is investigating the association between Streptococcus infection and tic disorders. The findings will shed light onto the pathogenesis of tic disorders and determine the genetic and environmental risk factors.