PRIME-A-PLANT

Priming of plant immunity: from its onset to trans-generational maintenance

Coordinatore	THE UNIVERSITY OF SHEFFIELD    more Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	1˙307˙407 €
EC contributo	1˙307˙407 €
Programma	FP7-IDEAS-ERC Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	ERC-2012-StG_20111109
Funding Scheme	ERC-SG
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-01-01   -   2017-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	THE UNIVERSITY OF SHEFFIELD  Organization address address: FIRTH COURT WESTERN BANK city: SHEFFIELD postcode: S10 2TN contact info Titolo: Dr. Nome: Jurriaan Cognome: Ton Email: send email Telefono: 441142000000 Fax: 441142000000	UK (SHEFFIELD)	hostInstitution	1˙307˙407.20
2	THE UNIVERSITY OF SHEFFIELD  Organization address address: FIRTH COURT WESTERN BANK city: SHEFFIELD postcode: S10 2TN contact info Titolo: Ms. Nome: Joanne Cognome: Watson Email: send email Telefono: +44 114 222 4754 Fax: +44 114 222 1452	UK (SHEFFIELD)	hostInstitution	1˙307˙407.20

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 Obiettivo del progetto (Objective)

'Plant defence depends on speed: the sooner a plant recognises its attacker, the more effective its defence response will be. Over the course of evolution, plants have acquired the ability to prime their immune system after perception of specific environmental signals. This heightened state of defence enables a faster and/or stronger activation of inducible defence mechanisms after pathogen attack, providing resistance against a wide range of diseases. Based on a phenotypically similar response in human immune cells, this plant resistance response is called “defence priming”. The primed defence state is not accompanied with an increased expression of costly defence mechanisms. Consequently, broad-spectrum disease resistance by defence priming is not associated with major reductions in plant growth and reproduction. Furthermore, defence priming can be maintained over a relatively long period of time, which is why it is often regarded as a form of immunological plant memory. Despite these attractive properties for application in sustainable agriculture, there are still many unanswered questions about the mechanistic basis of defence priming. The main objective of this ERC proposal is to elucidate the mechanisms underpinning two poorly understood aspects of the phenomenon:

1. the onset of primed defence. 2. the long-term maintenance of primed defence, including the intriguing phenomenon that the primed defence state can be transmitted from pathogen-exposed plants to their progeny.

Using state-of-the-art techniques in the field of molecular biology, biochemistry, and (epi)genetics, this project will address the overarching question of how plants adapt their immune system to the conditions in their environment. This project will allow me to generate new insights in the regulation of plant defence and provide tools that can be used to develop novel strategies for sustainable crop protection.'