SKELGEN

Establishment of a cross continent consortium for enhancing regenerative medicine in skeletal tissues

Coordinatore	UNIVERSITY OF LEEDS    more  Organization address address: WOODHOUSE LANE city: LEEDS postcode: LS2 9JT contact info Titolo: Mr. Nome: Martin Cognome: Hamilton Email: send email Telefono: +44 113 3434090 Fax: +44 113 3430949
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	168˙000 €
EC contributo	168˙000 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2012-IRSES
Funding Scheme	MC-IRSES
Anno di inizio	2012
Periodo (anno-mese-giorno)	2012-12-01   -   2016-11-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITY OF LEEDS  Organization address address: WOODHOUSE LANE city: LEEDS postcode: LS2 9JT contact info Titolo: Mr. Nome: Martin Cognome: Hamilton Email: send email Telefono: +44 113 3434090 Fax: +44 113 3430949	UK (LEEDS)	coordinator	29˙400.00
2	UNIVERSITY OF SOUTHAMPTON  Organization address address: Highfield city: SOUTHAMPTON postcode: SO17 1BJ contact info Titolo: Prof. Nome: Richard Cognome: Oreffo Email: send email Telefono: +44 2380 718502	UK (SOUTHAMPTON)	participant	27˙300.00
3	INSTITUTO POLITECNICO DE LEIRIA  Organization address address: Rua General Norton de Matos city: Leiria postcode: 2411-901 contact info Titolo: Prof. Nome: Paulo Jorge Cognome: Da Silva Bártolo Email: send email Telefono: +351 244 843 388 Fax: +351 244 820 310	PT (Leiria)	participant	25˙200.00
4	LOUGHBOROUGH UNIVERSITY  Organization address address: Ashby Road city: LOUGHBOROUGH postcode: LE11 3TU contact info Titolo: Dr. Nome: Christopher Cognome: Malins Email: send email Telefono: +44 1509 222421	UK (LOUGHBOROUGH)	participant	25˙200.00
5	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD  Organization address address: University Offices, Wellington Square city: OXFORD postcode: OX1 2JD contact info Titolo: Mr. Nome: Gill Cognome: Wells Email: send email Telefono: +44 1865 289800 Fax: +44 1865 289801	UK (OXFORD)	participant	25˙200.00
6	UNIVERSIDADE DO MINHO  Organization address address: Largo do Paco city: BRAGA postcode: 4704553 contact info Titolo: Prof. Nome: Rui L. Cognome: Reis Email: send email Telefono: +351 253 510900 Fax: +351 253 510909	PT (BRAGA)	participant	18˙900.00
7	UNIVERSITAIR MEDISCH CENTRUM UTRECHT  Organization address address: HEIDELBERGLAAN 100 city: UTRECHT postcode: 3584 CX contact info Titolo: Ms. Nome: Maggy Cognome: Ovaa Email: send email Telefono: 31887551339	NL (UTRECHT)	participant	16˙800.00
8	THE UNIVERSITY OF MANCHESTER  Organization address address: OXFORD ROAD city: MANCHESTER postcode: M13 9PL contact info Titolo: Ms. Nome: Liz Cognome: Fay Email: send email Telefono: 441613000000	UK (MANCHESTER)	participant	0.00

Mappa

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 Obiettivo del progetto (Objective)

'Regenerative medicine (RM) is a critical need to establish in this century, in order to raise quality of life and reduce the cost of healthcare in our increasing aged populations. To do this there is a need for key research teams within and outside the EU to develop meaningful research collaborations and relationships at an institutional level. skelGEN brings together leading research institutions across disciplines in biology/engineering/computational modelling/orthopaedic research in the EU (UK, the Netherlands, Portugal) partnered with complementary experts in New Zealand. This collaboration will allow EU partner institutions to work in a coordinated way to address RM in the human skeleton, including bones, cartilage and tendons/ligaments. This work will range from basic science through to translational medicine and involves world experts, emerging scientists as well as young researchers.

The programme of exchanges and knowledge transfer is built around four main scientific themes that will feed into each other, to pursue of skelGEN’s long term mission successfully. These themes are centred on stem cells, scaffolds and medical devices, computerised modelling and overall evaluation. Advances in stem cell therapy are required, such as pluripotent stem cells that do not have the political and ethical concerns of embryonic stem cell populations. Dynamic scaffolds need to respond to their environment and can integrate bioactive factors, using biocompatible biomaterials e.g. producing hybrid constructs of titanium rods and bulk polymers, self-assembling short peptides etc. to create better tissue/implant interfaces powerful for potential new therapies in RM. We plan to use computational modelling to assist in the tissue engineering of scaffolds and cells/tissues in vitro and in vivo. Finally we will endeavour to standardise the evaluation techniques used to assess the biocompatibility of these future medical devices.'