LIFEINVERSE

Variational Methods for Dynamic Inverse Problems in the Life Sciences

 Coordinatore WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER 

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 Nazionalità Coordinatore Germany [DE]
 Totale costo 966˙400 €
 EC contributo 966˙400 €
 Programma FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call ERC-2013-CoG
 Funding Scheme ERC-CG
 Anno di inizio 2014
 Periodo (anno-mese-giorno) 2014-03-01   -   2019-02-28

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER

 Organization address address: SCHLOSSPLATZ 2
city: MUENSTER
postcode: 48149

contact info
Titolo: Dr.
Nome: Katharina
Cognome: Steinberg
Email: send email
Telefono: +49 2518322151

DE (MUENSTER) hostInstitution 966˙400.00
2    WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER

 Organization address address: SCHLOSSPLATZ 2
city: MUENSTER
postcode: 48149

contact info
Titolo: Prof.
Nome: Martin
Cognome: Burger
Email: send email
Telefono: +0049 2518333793
Fax: +0049 25183

DE (MUENSTER) hostInstitution 966˙400.00

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equations    image    biology    related    efficient    partial    dynamic    sciences    variational    differential    time    imaging    life    models    solution    techniques    inverse   

 Obiettivo del progetto (Objective)

'This project will develop novel techniques for solving inverse problems in life sciences, in particular related to dynamic imaging. Major challenges in this area are efficient four- dimensional image reconstruction under low SNR conditions and further the quantification of image series as obtained from molecular imaging or life microscopy techniques. We will tackle both of them in a rather unified framework as inverse problems for time-dependent (systems of) partial differential equations. In the solution of these inverse problems we will investigate novel approaches for the following aspects specific to the above-mentioned problems in the life sciences:

1. Solution of inverse problems for PDEs in complex time-varying geometries 2. Development of appropriate variational regularization models for dynamic images, including noise and motion models 3. Improved forward and inverse modelling of cellular and intracellular dynamics leading to novel inverse problems for nonlinear partial differential equations 4. Construction and implementation of efficient iterative solution methods for the arising 4D inverse problems and their variational formulation

All tasks will be driven by concrete applications in biology and medicine and their success will be evaluated in applications to real problems and data. This is based on interdisciplinary work related to electrocardiology and developmental biology. The overall development of methods will however be carried out in a flexible and modular way, so that they become accessible for larger problem classes.'

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IMBALANCE-P (2014)

Effects of phosphorus limitations on Life, Earth system and Society

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MESANDLIN(G)K (2012)

The Linguistic Past of Mesoamerica and the Andes: A search for early migratory relations between North and South America

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ENLIGHTENED (2014)

Nanophotonic Nanomechanical Mass Spectrometry for Biology and Health

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