AVERT-IT
Advanced Arterial Hypotension Adverse Event prediction through a Novel Bayesian Neural Network
| Coordinatore | PERA INNOVATION LIMITED
Organization address
address: Innovation Park, Nottingham Road contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 2˙265˙890 € |
| EC contributo | 1˙780˙000 € |
| Programma | FP7-ICT
Specific Programme "Cooperation": Information and communication technologies |
| Code Call | FP7-ICT-2007-1 |
| Funding Scheme | CP |
| Anno di inizio | 2008 |
| Periodo (anno-mese-giorno) | 2008-01-01 - 2011-07-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
PERA INNOVATION LIMITED
Organization address
address: Innovation Park, Nottingham Road contact info |
UK (Melton Mowbray, Leicestershire) | coordinator | 0.00 |
| 2 |
AZIENDA OSPEDALIERA SAN GERARDO DI MONZA
Organization address
address: VIA PERGOLESI contact info |
IT (MONZA) | participant | 0.00 |
| 3 |
C3 GLOBAL LIMITED
Organization address
address: DRUIMCHAT VIEW - DINGWALL BUSINESS PARK contact info |
UK (DINGWALL) | participant | 0.00 |
| 4 |
GREATER GLASGOW HEALTH BOARD
Organization address
address: DALIAN HOUSE, 350 ST VINCENT STREET contact info |
UK (GLASGOW) | participant | 0.00 |
| 5 |
INSTITUT CATALA DE LA SALUT
Organization address
address: GRAN VIA DE LES CORTS CATALANES 587 contact info |
ES (BARCELONA) | participant | 0.00 |
| 6 |
KAUNO TECHNOLOGIJOS UNIVERSITETAS
Organization address
address: K DONELAICIO contact info |
LT (KAUNAS) | participant | 0.00 |
| 7 |
PHILIPS MEDIZIN SYSTEME BOBLINGEN GMBH
Organization address
address: HEWLETT-PACKARD-STRASSE 2 contact info |
DE (BOBLINGEN) | participant | 0.00 |
| 8 |
UNIVERSITAETSKLINIKUM HEIDELBERG
Organization address
address: IM NEUENHEIMER FELD 672 contact info |
DE (HEIDELBERG) | participant | 0.00 |
| 9 |
UNIVERSITY OF GLASGOW
Organization address
address: University Avenue contact info |
UK (GLASGOW) | participant | 0.00 |
| 10 |
UPPSALA UNIVERSITET
Organization address
address: St Olofsgatan contact info |
SE (UPPSALA) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
Hypotension (sub-normal blood pressure) adverse events (AE's) occur commonly in patients managed in intensive care and high dependency units. Health care technology which could reduce the burden of these events by as little as ten percent would equate to at least five billion Euros p.a. saved by European healthcare organisations for use in other treatment regimensnnThe AVERT-IT project will create a novel bed-side monitoring and alerting system dedicated to the prediction of variations in the condition of the patient that are likely to lead to hypotension without appropriate clinical intervention. A world-class consortium consisting of an SME software developer (C3 Global), renown clinical experts (www.brainit.org), Philips medical and Grid experts in secure access to distributed medical datasets will develop and validate the innovative technology using access to a unique and large repository of detailed multi-media patient data drawn from 22 clinical centres in 11 countries created through two recent EC funded projects.nnA systematic work programme will select appropriate clinical and monitoring inputs (via undertaking data mining and robust statistical analysis of this unique database and other electronic health record systems) to train a novel Bayesian Artificial Neural Network (BANN) to predict subsequent hypotension AE's. The BANN will form the engine of a novel IT-based decision support system ('HypoPredict') which will be prospectively validated in 6 clinical intensive care centres using a phase II clinical trial design.nnThe AVERT-IT project will produce a step-change in arterial hypotension prediction within the critical, intensive and high-dependency care environment with a major impact upon health care costs in terms of reduced corrective care, obviated as a consequence of the improved prediction of, and earlier intervention in, hypotension adverse events, and in improved patient outcome with associated reduction in carer-burden.