RANGER

"Rapid, robust & scaleable platform technology for fully automated reference laboratory grade Polymerase Chain Reaction (PCR) based diagnostics regardless of global setting"

Coordinatore	ENIGMA DIAGNOSTICS LIMITED    more  Organization address address: TETRICUS SCIENCE PARK PORTON DOWN Building 224 city: SALISBURY postcode: SP4 0JQ contact info Titolo: Dr. Nome: Ian Cognome: George Email: send email Telefono: +44 1980 590131 Fax: +44 1980 590132
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	4˙170˙658 €
EC contributo	2˙982˙200 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2007-A
Funding Scheme	CP-TP
Anno di inizio	2008
Periodo (anno-mese-giorno)	2008-07-01   -   2011-06-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	ENIGMA DIAGNOSTICS LIMITED  Organization address address: TETRICUS SCIENCE PARK PORTON DOWN Building 224 city: SALISBURY postcode: SP4 0JQ contact info Titolo: Dr. Nome: Ian Cognome: George Email: send email Telefono: +44 1980 590131 Fax: +44 1980 590132	UK (SALISBURY)	coordinator	0.00
2	BIOPHARMA TECHNOLOGY LTD  Organization address address: WINNALL VALLEY ROAD 9 city: WINCHESTER postcode: SO23 0LD contact info Titolo: Mr. Nome: Andrew Cognome: Cowen Email: send email Telefono: +44 1962 841092 Fax: +44 1962 841147	UK (WINCHESTER)	participant	0.00
3	BIOPLASTICS BV  Organization address address: ROTSCHERWEG 61 city: LANDGRAAF postcode: 6374 XW contact info Titolo: Mr. Nome: Tom Cognome: Hendrikx Email: send email Telefono: +31 45 533 8783 Fax: +31 45 533 8750	NL (LANDGRAAF)	participant	0.00
4	BRUHN NEWTECH A/S  Organization address address: GLADSAXEVEJ 402 city: SOEBORG postcode: 2860 contact info Titolo: Mr. Nome: Paul Cognome: Taylor Email: send email Telefono: +45 3955 8000	DK (SOEBORG)	participant	0.00
5	HEALTH PROTECTION AGENCY HPA  Organization address address: Central Office - 7th Floor, Holborn Gate - High Holborn 330 city: LONDON postcode: WC1V 7PP contact info Titolo: Dr. Nome: Tim Cognome: Brooks Email: send email Telefono: +44 1980 612774 Fax: +44 1980 610848	UK (LONDON)	participant	0.00
6	PERA INNOVATION LIMITED  Organization address address: Innovation Park, Nottingham Road city: MELTON MOWBRAY, LEICESTERSHIRE postcode: LE13 OPB contact info Titolo: Dr. Nome: Lydia Cognome: Lepecuchel Email: send email Telefono: +44 1664 501 317 Fax: +44 1664 501264	UK (MELTON MOWBRAY, LEICESTERSHIRE)	participant	0.00
7	QUEEN SIRIKIT NATIONAL INSTITUTE OF CHILD HEALTH  Organization address address: "420/8 Rajavithi Road, Rajthevi" city: BANGKOK postcode: 10400 contact info Titolo: Dr. Nome: Tawee Cognome: Chotpitayasunondh Email: send email Telefono: +662 354 8400 Fax: +662 354 8400	TH (BANGKOK)	participant	0.00
8	SAGENTIA GROUP LIMITED  Organization address address: HARSTON MILL city: HARSTON CAMBRIDGE postcode: CB22 7GG contact info Titolo: Mr. Nome: Daniel Cognome: Flicos Email: send email Telefono: +44 1223 875200 Fax: +44 1223 875201	UK (HARSTON CAMBRIDGE)	participant	0.00
9	Tico Europe Limited  Organization address address: SIDNEY STREET 80 city: FOLKESTONE postcode: CT19 6HQ contact info Titolo: Mr. Nome: Daniel Cognome: Van Akkeren Email: send email Telefono: +31 20 6408048 Fax: -	UK (FOLKESTONE)	participant	0.00

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 Obiettivo del progetto (Objective)

'RANGER addresses the HEALTH-2007-2.3.3-4: Innovative point-of-care (POC) diagnostic tests for influenza call by providing a innovative solution to the immediate need for a rapid, robust, cost effective & user friendly POC diagnostic for influenza. We will develop the following real-time PCR system: 1) A robust, portable system allowing testing at the POC anywhere in the world 2) Raw sample to result automation of the entire test process including sample preparation 3) Parallel processing of multiple samples & different sample types (aspirates & swabs) in a modular, user-friendly system 4) RAPID & simple positive/negative result to the end user 5) No need for an external computer or laboratory equipment 6) Low cost consumable & reagents with a target cost of < €10 per test 7) Sample preparation & freeze dried reagents pre-packaged into an ambient stable consumable to eliminate cold storage chains 8) High confidence PCR results providing sensitivity & specificity equivalent to reference laboratory assays a. Suitable for the diagnosis of early stage infections where viral titres can be low b. Applicable to late surveillance & can be used to confirm the results from lower cost, low performance screen tests such as antibody assays that have low sensitivity and specificity. c. Simultaneous identification of specific influenza strains & viral subtypes using multiplexing real-time PCR assays will also allow exclusion of related respiratory diseases 9) Surveillance Management software & geographical data using GPS, allowing health authorities to manage early stage epidemics. The RANGER consortium includes WHO reference sites for human influenza diagnostics & world leading companies to develop and validate a POC influenza diagnostic system within 2 years. This system will allow health systems to be better prepared for epidemics by enabling early identification of infection and thus timely implementation of containment/treatment strategies.'