EVONET
Evolution of gene regulatory networks in animal development
| Coordinatore | UNIVERSITAT WIEN
Organization address
address: UNIVERSITATSRING 1 contact info |
| Nazionalità Coordinatore | Austria [AT] |
| Totale costo | 2˙650˙000 € |
| EC contributo | 2˙650˙000 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2007-1-1-ITN |
| Funding Scheme | MC-ITN |
| Anno di inizio | 2008 |
| Periodo (anno-mese-giorno) | 2008-10-01 - 2012-09-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
UNIVERSITAT WIEN
Organization address
address: UNIVERSITATSRING 1 contact info |
AT (WIEN) | coordinator | 0.00 |
| 2 |
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Organization address
address: Meyerhofstrasse 1 contact info |
DE (HEIDELBERG) | participant | 0.00 |
| 3 |
MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT
Organization address
address: ROBERT ROSSLE STRASSE 10 contact info |
DE (BERLIN) | participant | 0.00 |
| 4 |
MEDICAL RESEARCH COUNCIL
Organization address
address: NORTH STAR AVENUE POLARIS HOUSE contact info |
UK (SWINDON) | participant | 0.00 |
| 5 |
STAZIONE ZOOLOGICA ANTON DOHRN
Organization address
address: Villa Comunale contact info |
IT (NAPOLI) | participant | 0.00 |
| 6 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Organization address
address: The Old Schools, Trinity Lane contact info |
UK (CAMBRIDGE) | participant | 0.00 |
| 7 |
UNI RESEARCH AS
Organization address
address: THORMOHLENS GATE 55 contact info |
NO (BERGEN) | participant | 0.00 |
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Obiettivo del progetto (Objective)
'Genetic and mutant analyses in Drosophila and other standard model organisms have revealed hierarchical gene networks and identified some key regulatory genes acting in animal development. While surprising conservation exists on a broad scale between distant phyla, significant differences have also been detected. Systems biology approaches in the main model systems have now revealed more complex gene regulatory networks (GRNs). To understand the logics and evolution of GRNs more basal animal phyla need to be studied. The comparative analysis of GRNs has thus become a new major focus of systems biology. The key questions are: (1) Does the higher complexity of some species correlate with an increase in complexity in GRNs? (2) How do GRNs evolve to drive changes in body plans? The major challenge for the next generation of researchers will be to integrate knowledge of developmental biology, bioinformatics, functional genomics and evolutionary biology. This requires a new combination of interdisciplinary training to bridge the gap between what are currently quite separate disciplines. In this ITN we will gather and compare information on GRNs from diverse animal systems, representing all major animal lineages, with particular emphases on the mesoderm specification network and the head regionalization network. To this end, we will provide early researchers with the skills necessary to apply state of the art systems biology, genomics and bioinformatics tools to emerging model organisms. The early researchers will receive an in-depth introduction into the selected model systems and training in how to conduct and analyze genomic experiments by the members of this ITN, which includes a company specialized in array technology. We will organize joint ITN/EMBO training courses and summer schools attended by three visiting renowned scientist, an exchange program between the ITN labs and a professional seminar in complementary skills.'