BOTRYTISGENOMICS

Genomics of the Botrytis cinerea grapevine interaction

Coordinatore	UNIVERSITE LYON 1 CLAUDE BERNARD    more  Organization address address: BOULEVARD DU 11 NOVEMBRE 1918 NUM43 city: VILLEURBANNE CEDEX postcode: 69622 contact info Titolo: Prof. Nome: Christophe Cognome: Bruel Email: send email Telefono: -72448164 Fax: -72431152
Nazionalità Coordinatore	France [FR]
Totale costo	224˙640 €
EC contributo	224˙640 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2007-2-1-IEF
Funding Scheme	MC-IEF
Anno di inizio	2009
Periodo (anno-mese-giorno)	2009-01-01   -   2010-12-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITE LYON 1 CLAUDE BERNARD  Organization address address: BOULEVARD DU 11 NOVEMBRE 1918 NUM43 city: VILLEURBANNE CEDEX postcode: 69622 contact info Titolo: Prof. Nome: Christophe Cognome: Bruel Email: send email Telefono: -72448164 Fax: -72431152	FR (VILLEURBANNE CEDEX)	coordinator	0.00

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 Obiettivo del progetto (Objective)

'The training objective of the proposed research is to complete the researcher’s existing knowledge in mycology and molecular biology by an interdisciplinary experience in infection physiology, genomics and modern bioinformatics, thus providing a boost for her career development and independence. The research objective of the project is to investigate fungal pathogenicity at the genomic level. The chosen model is the interaction between grapevine and grey mould because wine production plays an important role in European agriculture (several billion € market value), because grey mould is a major pathogen of this crop and because the high amounts of fungicides used to control the pathogen each year increase production cost and raise environmental issues. The genomes of the fungus B. cinerea and the plant V. vinifera have recently been sequenced, and the new available genomic tools should, for the first time, allow the drawing of an integrated view of the interaction between the pathogen and its host, and the deciphering of the largely unknown molecular mechanisms that support the fungus attack or the plant defence. As part of an effort to fully characterise the infection process, the aims of this project are 1) to identify the major fungal molecular players at work in the interaction between grapevine and B. cinerea and 2) the validation of these players in search of new targets for fungicides. Transcriptomic analyses of the infection will be performed using micro arrays, and a global profiling of the fungal genes will be obtained. Gene replacement will then be used to disrupt cellular functions highlighted by the genomics data, and analysis of the mutants will reveal the genes important in the infection process. This project should help develop control strategies that are novel, more efficient and/or environmentally safer. This project is lastly in harmony with the aims of the Community to structure EU research and to promote the participation of women in science.'