YLIDXCHEM
DEVELOPMENT AND APPLICATIONS OF NEW YLID CHEMISTRY
| Coordinatore | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Organization address
address: University Offices, Wellington Square contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 171˙867 € |
| EC contributo | 171˙867 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-IEF-2008 |
| Funding Scheme | MC-IEF |
| Anno di inizio | 2009 |
| Periodo (anno-mese-giorno) | 2009-07-01 - 2011-06-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Organization address
address: University Offices, Wellington Square contact info |
UK (OXFORD) | coordinator | 171˙867.62 |
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Obiettivo del progetto (Objective)
'The aims of this research are to develop efficient synthetic methodology for one-pot catalytic cross-metathesis/tandem oxonium ylide formation– [2,3] sigmatropic rearrangement of unsaturated diazocarbonyl substrates, to establish a pool of useful chiral catalysts for this chemistry, and to apply this methodology in strategies for the enantioselective synthesis of selected biologically active natural product classes. The objectives are: Development and scope of one-pot cross-metathesis/tandem oxonium ylide formation– [2,3] sigmatropic rearrangement New catalyst preparation and evaluation in enantioselective tandem ylide formation – rearrangement Development of asymmetric synthesis strategies to hyperolactone anti-HIV agents'