MIF/IMAGENE

MIF genes: key regulators of floral meristem termination at the cross talk of multihormonal pathways

 Coordinatore INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE 

 Organization address address: Rue De L'Universite 147
city: PARIS CEDEX 07
postcode: 75338

contact info
Titolo: Dr.
Nome: Christian
Cognome: Chevalier
Email: send email
Telefono: 33(0)557122693
Fax: 33(0)557122541

 Nazionalità Coordinatore France [FR]
 Totale costo 50˙000 €
 EC contributo 50˙000 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2009-RG
 Funding Scheme MC-IRG
 Anno di inizio 2010
 Periodo (anno-mese-giorno) 2010-05-01   -   2012-04-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE

 Organization address address: Rue De L'Universite 147
city: PARIS CEDEX 07
postcode: 75338

contact info
Titolo: Dr.
Nome: Christian
Cognome: Chevalier
Email: send email
Telefono: 33(0)557122693
Fax: 33(0)557122541

FR (PARIS CEDEX 07) coordinator 50˙000.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

shown    wuschel    signals    floral    cop    gene    mif    meristem    tomato    hormonal    termination    signalosome    proteins    regulate    plants    fruit    meristems    meristematic    ima    integration   

 Obiettivo del progetto (Objective)

'Plants have the ability to form new organs according to an indeterminate growth that is ensured by pluripotent cells in organized structures called meristems. During floral induction the shoot apical meristem is converted into an inflorescence meristem, which gives rise to floral meristems (FM) leading to flower formation. This process called floral termination is under the control of the meristematic organizer gene WUSCHEL (WUS). The meristematic activity is intimately linked to hormonal signaling. However little is known about the integration of multi-hormonal signals during floral development. Recently, MIni Zinc Finger (MIF) proteins have been characterized in Arabidopsis, and shown to be involved in multiple hormonal regulations during plant development. Previously we isolated a gene named INHIBITOR OF MERISTEM ACTIVITY (IMA) as a tomato MIF ortholog. IMA was shown to regulate meristem activity by inhibiting the expression of WUSCHEL. Tomato plants overexpressing IMA exhibit a dwarf phenotype suggesting that IMA regulates negatively cell proliferation and expansion. A Two-Hybrid screen contributed to identify the COP9-signalosome subunit 5, as a strong interacting protein. The COP9-signalosome plays a conserved key role in the integration of endogenous and exogenous signals to regulate growth of eukaryotic organisms, including cancer development in human when a deregulation of this complex occurs. Our data suggest that IMA controls COP9-signalosome activity to modulate multihormonal responses during meristem development and floral termination. This project aims at understanding the molecular and genetic mechanisms by which IMA and more generally MIF proteins are involved in such regulatory pathways. In the context of fleshy fruit development, this innovative project will promote fundamental knowledge on an original model, but also will generate agronomical benefits through applications at the breeding and biotechnological level for fruit quality improvement.'

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