MANUCYTE

"Self-learning modular manufacturing platform for flexible, patient-specific cell production"

Coordinatore	FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V    more  Organization address address: Hansastrasse 27C city: MUENCHEN postcode: 80686 contact info Titolo: Mr. Nome: Walter Cognome: Krause Email: send email Telefono: +49 89 12052713 Fax: +49 89 12057534
Nazionalità Coordinatore	Germany [DE]
Sito del progetto	http://www.manucyte-project.eu
Totale costo	4˙534˙238 €
EC contributo	3˙435˙700 €
Programma	FP7-NMP Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies
Code Call	FP7-2010-NMP-ICT-FoF
Funding Scheme	CP
Anno di inizio	2010
Periodo (anno-mese-giorno)	2010-05-01   -   2013-04-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V  Organization address address: Hansastrasse 27C city: MUENCHEN postcode: 80686 contact info Titolo: Mr. Nome: Walter Cognome: Krause Email: send email Telefono: +49 89 12052713 Fax: +49 89 12057534	DE (MUENCHEN)	coordinator	930˙460.00
2	Chip-Man Technologies Oy  Organization address address: Biokatu 12 city: Tampere postcode: 33520 contact info Titolo: Dr. Nome: Jane Cognome: Spencer-Fry Email: send email Telefono: +44 7881 557511 Fax: +358 10 759 5930	FI (Tampere)	participant	488˙737.60
3	UNITECHNOLOGIES SA  Organization address address: Route de Berne 5 city: Gals postcode: 3238 contact info Titolo: Mr. Nome: Bruno Cognome: Thomann Email: send email Telefono: 41323388250 Fax: +41 32 338 82 29	CH (Gals)	participant	480˙760.00
4	ABO AKADEMI  Organization address address: DOMKYRKOTORGET 3 city: ABO postcode: 20500 contact info Titolo: Prof. Nome: John E. Cognome: Eriksson Email: send email Telefono: +358 2 333 8036 Fax: +358 2 333 8000	FI (ABO)	participant	350˙962.00
5	ADVANCED CLEAN PRODUCTION INFORMATION TECHNOLOGY AKTIENGESELLSCHAFT  Organization address address: Handwerkstrasse 29 city: Stuttgart postcode: 70565 contact info Titolo: Dr. Nome: Frank Cognome: Frauenhoffer Email: send email Telefono: +49 711 782408921 Fax: +49 711 782408910	DE (Stuttgart)	participant	311˙970.00
6	HOCHSCHULE REGENSBURG  Organization address address: PRUFENINGER STRASSE 58 city: REGENSBURG postcode: 93049 contact info Titolo: Prof. Nome: Thomas Cognome: Schlegl Email: send email Telefono: +49 941 943 5180 Fax: +49 941 943 5294	DE (REGENSBURG)	participant	291˙700.00
7	AFT AUTOMATION UND FEINWERKTECHNIK GMBH  Organization address address: CARL ZEISS STRASSE 4-6 city: OLBRONN DURRN postcode: 75248 contact info Titolo: Mr. Nome: Wolfgang Cognome: Bauer Email: send email Telefono: +49 7237 426 12 Fax: +49 7237 426 66	DE (OLBRONN DURRN)	participant	251˙418.00
8	MAGYAR TUDOMANYOS AKADEMIA SZAMITASTECHNIKAI ES AUTOMATIZALASI KUTATO INTEZET  Organization address address: Kende utca 13-17 city: BUDAPEST postcode: 1111 contact info Titolo: Dr. Nome: Geza Cognome: Haidegger Email: send email Telefono: +36 1 2796224 Fax: +36 1 4667503	HU (BUDAPEST)	participant	214˙380.00
9	PRIMACYT CELL CULTURE TECHNOLOGY GMBH  Organization address address: HAGENOWER STRASSE 73 city: SCHERIN postcode: 19061 contact info Titolo: Dr. Nome: Dieter Cognome: Runge Email: send email Telefono: +49 385 3993 600 Fax: +49 385 3993 602	DE (SCHERIN)	participant	115˙312.40
10	MTA AUTOMATION AG  Organization address address: Bernstrasse 5 city: Gals postcode: 3238 contact info Titolo: Mr. Nome: Bruno Cognome: Thomann Email: send email Telefono: 41323388250 Fax: +41 32 338 82 29	CH (Gals)	participant	0.00

Mappa

 Word cloud

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 Obiettivo del progetto (Objective)

'Personalized medicine (e.g. regenerative, such as cell therapy or patient-specific tested and composed pharmaceuticals) has huge potential. But to exploit this potential, it is necessary to produce human cells patient-specific in industrial scale. Nowadays, personalized cell production is only executed by means of manual processing on laboratory scale. In Order to make patient-specific production of cells available for a wide range of applications, CytoFab focuses on the development of an intelligent, modular manufacturing platform for flexible, patient-specific cell production which will increase efficiency of personalised cell production in quality and throughput. This objective will be reached by combining several high-sophisticated technologies such as a modular and scalable plug-in concept for the setup of cell production platforms, the application of a cleanroom and sterilisation concept to keep cell cultures cross-contamination free, a micro-fluidic component for customized cell culture medium composition, inline monitoring methodologies to enable the evaluation of cell status within the production process, and a manufacturing execution system which includes a self-learning knowledge-based cell behaviour and advanced cell process control fuctionalities for self-optimization of cell production processes. The latter is needed due to the individual nature of cells which makes it impossible, to process each cell with the same parameters without considerable variations in quality. With this high grade innovations, CytoFab will set a new standard in automated manufacturing technologies for personalized medicine applications.'

Introduzione (Teaser)

Personalised medicine through industrial-scale patient-specific cell production can revolutionise health care and improve patient outcomes with minimal rejection of cell products. Unfortunately, current cell production processes are manual or semi-automated at laboratory-scale and subject to human errors, thus affecting accuracy, reproducibility, quality and efficiency.