DYNAREP

Self-Replication in Dynamic Combinatorial Libraries

Coordinatore	RIJKSUNIVERSITEIT GRONINGEN    more  Organization address address: Broerstraat 5 city: GRONINGEN postcode: 9712CP contact info Titolo: Dr. Nome: H.D. Cognome: Veldhuis Email: send email Telefono: +31 50 3634142 Fax: +31 50 3634500
Nazionalità Coordinatore	Netherlands [NL]
Totale costo	169˙035 €
EC contributo	169˙035 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2009-IEF
Funding Scheme	MC-IEF
Anno di inizio	2011
Periodo (anno-mese-giorno)	2011-02-01   -   2013-01-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	RIJKSUNIVERSITEIT GRONINGEN  Organization address address: Broerstraat 5 city: GRONINGEN postcode: 9712CP contact info Titolo: Dr. Nome: H.D. Cognome: Veldhuis Email: send email Telefono: +31 50 3634142 Fax: +31 50 3634500	NL (GRONINGEN)	coordinator	169˙035.20

Mappa

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 Obiettivo del progetto (Objective)

'The host group has recently made a remarkable discovery: the spontaneous emergence of self-replicating molecules from a complex mixture of continuously interconverting peptide-derived compounds (dynamic combinatorial libraries). This project builds on this discovery and aims to come to a complete understanding of the mechanism of replication. Based on this understanding new replicators will then be developed. In the final stage the process of replication will be studied inside bilayer vesicles. If successful this will be the first example of a fully synthetic system that combines three important elements found in living systems: metabolism, replication and compartmentalization. Success of the project is critically dependent on combining the expertise of the host on dynamic combinatorial chemistry with the expertise of the researcher on the permeation of peptides through bilayer membranes.'