WW-NMR

Word Wide NMR

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 Obiettivo del progetto (Objective)

and institutions specialised in all aspects of NMR spectroscopy in Europe with newly developed laboratories in five other countries. It builds on EU-funded infrastructures and will enable the creation of strategic and sustainable links with nine Partners from countries outside Europe. In return Third Country Partners will gain access to highly sophisticated NMR equipment. NMR spectroscopy is a broadly applicable technology relevant to all aspects of Life Science research, with major influence and impact on the biomedical industries. The specific objectives will be reached through mutually beneficial collaborations: SO1: Increasing awareness of the potential of NMR spectroscopy in essentially all areas of Life Sciences. Mutual advancement of the research portfolio of the Partners involved through global networking, training in advanced technologies and meetings to present cutting edge research projects. SO2: Building joint collaborative projects for liquid-state and solid-state NMR investigations by providing access to NMR instrumentation, focussed on investigations of drug targets such as kinases, phosphatases, metalloproteinases, bromo domains, membrane proteins and their complexes with agonists and antagonists. SO3: Learning and participating in training and application in the field of metabolomics research. Building a world-wide agenda for the role of metabolomics in diagnosis, predictive and individualised medicine supporting human health programmes and in fundamental research in the context of a mechanistic systems biology view to cellular function. This project will support and reinforce the collaborative interactions amongst the participants and help to establish long-term research co-operation. Most importantly, WW-NMR will enable Europe to lead the agenda for future NMR activities on an international platform.

Introduzione (Teaser)

An EU-funded project has pulled together Europe's leading nuclear magnetic resonance (NMR) facilities with the aim of fostering transnational collaboration in all areas of life sciences.

Descrizione progetto (Article)

NMR spectroscopy has applications in several areas of life sciences. Scientists can obtain information about the atomic structure of biologically significant molecules and their complexes with the help of this technology. In particular, by examining small molecules called metabolites, they can detect changes in cell behaviour and organ function.

The EU-funded project 'World wide NMR' (WW-NMR) was launched to provide much-needed support for research using NMR techniques by mobilising tools and expertise. Six leading national laboratories joined their forces to offer researchers access to the most advanced NMR spectrometers as well as to promote networking and joint research efforts.

Through past EU-funded initiatives, WW-NMR partners had established a distributed yet cohesive continental research infrastructure. Scientists across Europe had access to state-of-the-art NMR spectrometers and ancillary equipment for the preparation of biological samples. The consortium was, therefore, in the position to build mutually beneficial relationships with research groups in five other countries.

Its instruments were the WW-NMR workshops and staff exchanges. Three joint scientific workshops were organised in Beijing (China), Hyderabad (India) and Rio de Janeiro (Brazil), covering recent advances in NMR technology and findings of metabolomics research. Secondments from Asia and South America to Europe exceeded 40 months.

The collaborations built with newly developed research groups in other parts of the world increased the visibility of NMR-based research carried out at European NMR laboratories. More importantly, the WW-NMR project is expected to enable Europe to lead the agenda on NMR and metabolomics research at an international level.