Coordinatore | UNIVERSITY OF NEWCASTLE UPON TYNE
Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie. |
Nazionalità Coordinatore | United Kingdom [UK] |
Totale costo | 1˙998˙703 € |
EC contributo | 1˙998˙703 € |
Programma | FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
Code Call | ERC-2010-AdG_20100317 |
Funding Scheme | ERC-AG |
Anno di inizio | 2011 |
Periodo (anno-mese-giorno) | 2011-03-01 - 2017-02-28 |
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1 |
UNIVERSITY OF NEWCASTLE UPON TYNE
Organization address
address: Kensington Terrace 6 contact info |
UK (NEWCASTLE UPON TYNE) | hostInstitution | 1˙998˙703.00 |
2 |
UNIVERSITY OF NEWCASTLE UPON TYNE
Organization address
address: Kensington Terrace 6 contact info |
UK (NEWCASTLE UPON TYNE) | hostInstitution | 1˙998˙703.00 |
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'Understanding the origin and evolution of eukaryotes, their genomes and organelles, are among the most important and exciting challenges facing biology. However, determining ancient gene origins tests methods and data to their limits, and it is unrealistic to expect progress to be easy. A comparative cross-disciplinary approach involving sophisticated phylogenetics allied with mathematical understanding, offers the best hope of obtaining robust hypotheses for gene and genomic origins. It is also necessary to look beyond the narrow focus of a few model organisms, and to thoughtfully embrace a wider selection of eukaryotic diversity. Over the past few years, my lab has studied the genomes and mitochondrial homologues (mitosomes and hydrogenosomes) of parasitic protozoa that represent significant health hazards in both the developed and developing world. These microbial eukaryotes will provide the model systems for investigations which aim to deliver major progress in understanding the importance of lateral gene transfer for eukaryotic genome origins and flux, for understanding how parasites exploit their host cells, and for identifying the essential functions of organelles related to mitochondria, which now appear to be vital components of all eukaryotic cells.'
Reverse engineering of vascular patterning through mosaic in vivo analysis of endothelial cell shape regulation
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