IDEAL
Integrated research on DEvelopmental determinants of Aging and Longevity
| Coordinatore | ACADEMISCH ZIEKENHUIS LEIDEN
Organization address
address: Albinusdreef 2 contact info |
| Nazionalità Coordinatore | Netherlands [NL] |
| Sito del progetto | http://www.idealageing.eu |
| Totale costo | 15˙935˙888 € |
| EC contributo | 11˙986˙951 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2010-two-stage |
| Funding Scheme | CP-IP |
| Anno di inizio | 2011 |
| Periodo (anno-mese-giorno) | 2011-02-01 - 2016-01-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
ACADEMISCH ZIEKENHUIS LEIDEN
Organization address
address: Albinusdreef 2 contact info |
NL (LEIDEN) | coordinator | 2˙251˙187.50 |
| 2 |
WAGENINGEN UNIVERSITY
Organization address
address: DROEVENDAALSESTEEG 4 contact info |
NL (WAGENINGEN) | participant | 1˙742˙489.50 |
| 3 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Organization address
address: Rue Michel -Ange 3 contact info |
FR (PARIS) | participant | 1˙189˙218.00 |
| 4 |
UNIVERSITY COLLEGE LONDON
Organization address
address: GOWER STREET contact info |
UK (LONDON) | participant | 1˙173˙468.80 |
| 5 |
UNIVERSITY OF SOUTHAMPTON
Organization address
address: Highfield contact info |
UK (SOUTHAMPTON) | participant | 1˙027˙498.75 |
| 6 |
KAROLINSKA INSTITUTET
Organization address
address: Nobels Vag 5 contact info |
SE (STOCKHOLM) | participant | 687˙359.75 |
| 7 |
ALMA MATER STUDIORUM-UNIVERSITA DI BOLOGNA
Organization address
address: Via Zamboni 33 contact info |
IT (BOLOGNA) | participant | 660˙000.00 |
| 8 |
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Organization address
address: BATIMENT CE 3316 STATION 1 contact info |
CH (LAUSANNE) | participant | 630˙000.00 |
| 9 |
SYDDANSK UNIVERSITET
Organization address
address: CAMPUSVEJ 55 contact info |
DK (ODENSE M) | participant | 543˙960.00 |
| 10 |
UNIVERSITA DELLA CALABRIA
Organization address
address: Via Pietro Bucci 7/11 B contact info |
IT (ARCAVACATA DI RENDE) | participant | 483˙250.00 |
| 11 |
EBERHARD KARLS UNIVERSITAET TUEBINGEN
Organization address
address: GESCHWISTER-SCHOLL-PLATZ contact info |
DE (TUEBINGEN) | participant | 464˙400.00 |
| 12 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Organization address
address: University Offices, Wellington Square contact info |
UK (OXFORD) | participant | 380˙286.60 |
| 13 |
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH
Organization address
address: Raemistrasse 101 contact info |
CH (ZUERICH) | participant | 344˙400.00 |
| 14 |
ServiceXS BV
Organization address
address: Plesmanlaan 1.d contact info |
NL (Leiden) | participant | 241˙440.00 |
| 15 |
NORDIC BIOSCIENCE COMPOUND DEVELOPMENT A/S
Organization address
address: Herlev Hovedgade 207 contact info |
DK (Helev) | participant | 100˙000.00 |
| 16 |
UNIVERSITEIT LEIDEN
Organization address
address: RAPENBURG 70 contact info |
NL (LEIDEN) | participant | 67˙992.00 |
Mappa
Word cloud
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Obiettivo del progetto (Objective)
'IDEAL will obtain insight into the role of early life conditions affecting late-life health, disease and aging, and the role of epigenetic regulation therein. IDEAL will identify the determinants and targets of this epigenetic regulation utilizing a resource of unique human cohorts and animal studies that allow testing of hypotheses on the link between development and aging. Key objectives of IDEAL are 1.Quantify the role of epigenetic regulation in the response to developmental conditions that affect growth & metabolism, immunity, and reproduction in animal models and its translation to human conditions. 2.Quantify the role of epigenetic regulation in the response to developmental conditions of humans and create the animal model that resembles such responses. 3.Create a reference library of gene expression and epigenetic changes as a function of age and obtain insight into principles of epigenetic regulation across species. 4.Develop monitoring tools of epigenetic effects following developmental conditions. 5.Develop monitoring tools of epigenetic control during aging and their meaning for physiological functions, and for the development of biomarkers of aging 6.Identify pathways determining and promoting human longevity. 7.Identify pathways determining human health and longevity by influencing developmental processes. 8.Develop animal models for testing relevant compounds to modify epigenetic effects early or later in life. We will study known longevity determinants as well as newly discovered pathways, and we will link early development with all adult phases. Our research can provide models for testing interventions through epigenetic regulation that improves healthy aging and longevity and that can be translated into novel drug targets and protein therapeutics. IDEAL integrates expertise, resources and results of some of the best EU projects on ageing and has the potential to reshape health-care for a healthier and longer life in the EU.'
Introduzione (Teaser)
Researchers in the EU are studying humans, animals, plants and even fungi to better understand how early life events influence the ageing process.