Explore the words cloud of the EUROPOL project. It provides you a very rough idea of what is the project "EUROPOL" about.
The following table provides information about the project.
Coordinator |
THE UNIVERSITY OF BIRMINGHAM
Organization address contact info |
Coordinator Country | United Kingdom [UK] |
Project website | http://itn-europol.eu |
Total cost | 3˙960˙039 € |
EC max contribution | 3˙960˙039 € (100%) |
Programme |
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers) |
Code Call | H2020-MSCA-ITN-2014 |
Funding Scheme | MSCA-ITN-ETN |
Starting year | 2015 |
Duration (year-month-day) | from 2015-01-01 to 2019-08-31 |
Take a look of project's partnership.
NMR and MRI play unique roles in contemporary Science, from Physics, Chemistry and Biology, to clinical research and diagnosis. Despite its irreplaceable role, further progress in NMR and MRI is hampered by sensitivities that are much lower than those of alternatives such as mass-spec, or PET. The prospects of solving this problem by “bigger machines” are uncertain and of poor return, given the high maturity already achieved by NMR/MRI. This ETN challenges this status from an untapped perspective, combining NMR/MRI with nuclear hyperpolarization eliciting signals that surpass those currently available by up to 50,000x. Focus is placed on two particular approaches, dynamic nuclear polarization and para-hydrogen-driven polarization, exhibiting the highest potential for biophysical, metabolomic, pre-clinical and clinical research. To maximize these “supersignals” we assembled leading experts in the physics and engineering of magnetic resonance, in the synthetic chemistry essential for the success of these methods, in the uses of NMR to structural/cell biology, and in preclinical and clinical MRI applications. Guiding this assembling is the conception that only by teaming together key areas of expertise, can hyperpolarisation’s promises be realized. In addition to fostering synergies among experts from academia and industry, EUROPOL will provide frontier training for ESRs in all the topics underlying the advancement of MR. This will include advanced physics, new instruments and forms of exploiting NMR/MRI’s hyperpolarisation, biophysical NMR, screening of healthy and diseased metabolomes, expanded portfolios of substrates to be targeted by in vivo MR, ancillary in cell and system biology explorations clarifying the nature of the metabolic phenomena, and in vivo hyperpolarisation strategies in MRI. This ETN is unparalleled in scope, breadth and potential for synergies.
Outreach activities (ETN open days, podcast, eNewsletter etc) 2 | Other | 2020-02-27 14:53:25 |
Outreach activities (ETN open days, podcast, eNewsletter etc) 3 | Other | 2020-02-27 14:53:30 |
Outreach activities (ETN open days, podcast, eNewsletter etc) 1 | Other | 2019-07-10 14:43:24 |
Take a look to the deliverables list in detail: detailed list of EUROPOL deliverables.
year | authors and title | journal | last update |
---|---|---|---|
2018 |
Patrick Seyfried, Marcel Heinz, György Pintér, Dean-Paulos Klötzner, Yvonne Becker, Michael Bolte, Hendrik R. A. Jonker, Lukas S. Stelzl, Gerhard Hummer, Harald Schwalbe, Alexander Heckel Optimal Destabilization of DNA Double Strands by Single-Nucleobase Caging published pages: 17568-17576, ISSN: 0947-6539, DOI: 10.1002/chem.201804040 |
Chemistry - A European Journal 24/66 | 2019-11-12 |
2018 |
Patrick Seyfried, Marcel Heinz, György Pintér, Dean-Paulos Klötzner, Yvonne Becker, Michael Bolte, Hendrik R. A. Jonker, Lukas S. Stelzl, Gerhard Hummer, Harald Schwalbe, Alexander Heckel Optimal Destabilization of DNA Double Strands by Single-Nucleobase Caging published pages: 17568-17576, ISSN: 0947-6539, DOI: 10.1002/chem.201804040 |
Chemistry - A European Journal 24/66 | 2019-10-31 |
2019 |
Raquel Saborano, Zuhal Eraslan, Jennie Roberts, Farhat L. Khanim, Patricia F. Lalor, Michelle A. C. Reed, Ulrich L. Günther A framework for tracer-based metabolism in mammalian cells by NMR published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-37525-3 |
Scientific Reports 9/1 | 2019-09-17 |
2019 |
Joachim M.O. Vinther, Vitaliy Zhurbenko, Mohammed M. Albannay, Jan Henrik Ardenkjær-Larsen Design of a local quasi-distributed tuning and matching circuit for dissolution DNP cross polarization published pages: 12-20, ISSN: 0926-2040, DOI: 10.1016/j.ssnmr.2019.04.006 |
Solid State Nuclear Magnetic Resonance 102 | 2019-09-17 |
2018 |
Mihajlo Novakovic, Samuel F. Cousin, Michael J. Jaroszewicz, Rina Rosenzweig, Lucio Frydman Looped-PROjected SpectroscopY (L-PROSY): A simple approach to enhance backbone/sidechain cross-peaks in 1 H NMR published pages: 169-180, ISSN: 1090-7807, DOI: 10.1016/j.jmr.2018.07.010 |
Journal of Magnetic Resonance 294 | 2019-09-17 |
2019 |
Martins Otikovs, Gregory L. Olsen, EÌ…riks KupÄe, Lucio Frydman Natural Abundance, Single-Scan 13 C– 13 C-Based Structural Elucidations by Dissolution DNP NMR published pages: 1857-1861, ISSN: 0002-7863, DOI: 10.1021/jacs.8b12216 |
Journal of the American Chemical Society 141/5 | 2019-09-17 |
2018 |
Mihajlo Novakovic, Ricardo P. Martinho, Gregory L. Olsen, Michael S. Lustig, Lucio Frydman Sensitivity-enhanced detection of non-labile proton and carbon NMR spectra on water resonances published pages: 56-62, ISSN: 1463-9076, DOI: 10.1039/c7cp07046b |
Physical Chemistry Chemical Physics 20/1 | 2019-09-17 |
2017 |
Alessia Michelotti, Fabien Rodrigues, Maxime Roche Development and Scale-Up of Stereoretentive α-Deuteration of Amines published pages: 1741-1744, ISSN: 1083-6160, DOI: 10.1021/acs.oprd.7b00227 |
Organic Process Research & Development 21/11 | 2019-09-17 |
2018 |
Soumya S. Roy, Kate M. Appleby, Elizabeth J. Fear, Simon B. Duckett SABRE-Relay: A Versatile Route to Hyperpolarization published pages: 1112-1117, ISSN: 1948-7185, DOI: 10.1021/acs.jpclett.7b03026 |
The Journal of Physical Chemistry Letters 9/5 | 2019-09-17 |
2019 |
Mohammed M. Albannay, Joachim M.O. Vinther, Andrea Capozzi, Vitaliy Zhurbenko, Jan Henrik Ardenkjaer-Larsen Optimized microwave delivery in dDNP published pages: 58-65, ISSN: 1090-7807, DOI: 10.1016/j.jmr.2019.06.004 |
Journal of Magnetic Resonance 305 | 2019-09-17 |
2019 |
Mohammed M. Albannay, Joachim M.O. Vinther, Jan Raagaard Petersen, Vitaliy Zhurbenko, Jan Henrik Ardenkjaer-Larsen Compact, low-cost NMR spectrometer and probe for dissolution DNP published pages: 7-15, ISSN: 1090-7807, DOI: 10.1016/j.jmr.2019.04.016 |
Journal of Magnetic Resonance 304 | 2019-09-17 |
2019 |
D.H. Johansen, M.M. Albannay, J.R. Petersen, V. Zhurbenko, J.H. Ardenkjær-Larsen PIN diode driver for NMR and MRI published pages: 114-119, ISSN: 1090-7807, DOI: 10.1016/j.jmr.2019.01.017 |
Journal of Magnetic Resonance 300 | 2019-09-17 |
2019 |
Gil Farkash, Stefan Markovic, Mihajlo Novakovic, Lucio Frydman Enhanced hyperpolarized chemical shift imaging based on a priori segmented information published pages: 3080-3093, ISSN: 0740-3194, DOI: 10.1002/mrm.27631 |
Magnetic Resonance in Medicine 81/5 | 2019-09-17 |
2018 |
Alexandra M. Olaru, Thomas B. R. Robertson, Jennifer S. Lewis, Alex Antony, Wissam Iali, Ryan E. Mewis, Simon B. Duckett Extending the Scope of 19 F Hyperpolarization through Signal Amplification by Reversible Exchange in MRI and NMR Spectroscopy published pages: 97-105, ISSN: 2191-1363, DOI: 10.1002/open.201700166 |
ChemistryOpen 7/1 | 2019-09-17 |
2019 |
Andrea Capozzi, Saket Patel, Christine Pepke Gunnarsson, Irene Marco-Rius, Arnaud Comment, Magnus Karlsson, Mathilde H. Lerche, Olivier Ouari, Jan Henrik Ardenkjaer-Larsen Efficient Hyperpolarization of U- 13 C-Glucose Using Narrow-Line UV-Generated Labile Free Radicals published pages: 1334-1339, ISSN: 1433-7851, DOI: 10.1002/anie.201810522 |
Angewandte Chemie International Edition 58/5 | 2019-07-10 |
2018 |
Dmitry Shishmarev, Philip W. Kuchel, Guilhem Pagès, Alan J. Wright, Richard L. Hesketh, Felix Kreis, Kevin M. Brindle Glyoxalase activity in human erythrocytes and mouse lymphoma, liver and brain probed with hyperpolarized 13C-methylglyoxal published pages: , ISSN: 2399-3642, DOI: 10.1038/s42003-018-0241-1 |
Communications Biology 1/1 | 2019-07-10 |
2016 |
Michael J. Jaroszewicz, Lucio Frydman, Robert W. Schurko Relaxation-Assisted Separation of Overlapping Patterns in Ultra-Wideline NMR Spectra published pages: 51-65, ISSN: 1089-5639, DOI: 10.1021/acs.jpca.6b10007 |
The Journal of Physical Chemistry A 121/1 | 2019-07-10 |
2018 |
Jiazheng Wang, Felix Kreis, Alan J. Wright, Richard L. Hesketh, Malcolm H. Levitt, Kevin M. Brindle Dynamic 1 H imaging of hyperpolarized [1- 13 C]lactate in vivo using a reverse INEPT experiment published pages: 741-747, ISSN: 0740-3194, DOI: 10.1002/mrm.26725 |
Magnetic Resonance in Medicine 79/2 | 2019-07-10 |
2017 |
Ricardo P. Martinho, Mihajlo Novakovic, Gregory L. Olsen, Lucio Frydman Heteronuclear 1D and 2D NMR Resonances Detected by Chemical Exchange Saturation Transfer to Water published pages: 3521-3525, ISSN: 1433-7851, DOI: 10.1002/anie.201611733 |
Angewandte Chemie International Edition 56/13 | 2019-07-10 |
2018 |
Jason Graham Skinner, Luca Menichetti, Alessandra Flori, Anna Dost, Andreas Benjamin Schmidt, Markus Plaumann, Ferdia Aiden Gallagher, Jan-Bernd Hövener Metabolic and Molecular Imaging with Hyperpolarised Tracers published pages: 902-918, ISSN: 1536-1632, DOI: 10.1007/s11307-018-1265-0 |
Molecular Imaging and Biology 20/6 | 2019-07-10 |
2018 |
Irene Marco-Rius, Tian Cheng, Adam P. Gaunt, Saket Patel, Felix Kreis, Andrea Capozzi, Alan J. Wright, Kevin M. Brindle, Olivier Ouari, Arnaud Comment Photogenerated Radical in Phenylglyoxylic Acid for in Vivo Hyperpolarized 13 C MR with Photosensitive Metabolic Substrates published pages: 14455-14463, ISSN: 0002-7863, DOI: 10.1021/jacs.8b09326 |
Journal of the American Chemical Society 140/43 | 2019-07-10 |
2018 |
Richard Mair, Alan J. Wright, Susana Ros, De-en Hu, Tom Booth, Felix Kreis, Jyotsna Rao, Colin Watts, Kevin M. Brindle Metabolic Imaging Detects Low Levels of Glycolytic Activity That Vary with Levels of c-Myc Expression in Patient-Derived Xenograft Models of Glioblastoma published pages: 5408-5418, ISSN: 0008-5472, DOI: 10.1158/0008-5472.can-18-0759 |
Cancer Research 78/18 | 2019-07-10 |
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