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PALADIN

Positron Annihilation Detection Beyond the Limits

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

PALADIN project word cloud

Explore the words cloud of the PALADIN project. It provides you a very rough idea of what is the project "PALADIN" about.

population health spatial physical sub picosecond overcome isotropic characterization surfaces photon tof solutions treatment 90 mm detectors limits staging arrays world given scintillation monolithic bottleneck delft digital tu time technologies science detection renewable spectroscopy crt crystals energy 10 times influence effect fwhm energies emission flight physics aging coupled read monitoring ing incorporated innovative lt eliminate relevance resolving clinical performance nevertheless serve materials play resolution counter annihilation cherenkov lifetime detector positron setup options storage improvement material 100ps coincidence dpc pet sustainable unprecedented quanta hybrid deteriorate propagation proof efficiency realization medicine tomography diseases diagnosis data pals

Project "PALADIN" data sheet

The following table provides information about the project.

Coordinator	TECHNISCHE UNIVERSITEIT DELFT Organization address address: STEVINWEG 1 city: DELFT postcode: 2628 CN website: www.tudelft.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Project website	http://fasttiming.weebly.com
Total cost	165˙598 €
EC max contribution	165˙598 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2014
Funding Scheme	MSCA-IF-EF-ST
Starting year	2015
Duration (year-month-day)	from 2015-09-01 to 2017-11-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	TECHNISCHE UNIVERSITEIT DELFT TECHNISCHE UNIVERSITEIT DELFT Organization address address: STEVINWEG 1 city: DELFT postcode: 2628 CN website: www.tudelft.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (DELFT)	coordinator	165˙598.00

Map

Project objective

Given the growth and aging of the world population, innovative solutions for sustainable energy and health are needed. Novel technologies play an enabling role in the realization of such solutions. Better devices for the detection of annihilation quanta resulting from positron annihilation are an example. In material science these detectors are needed for research on renewable energies and innovative energy storage using Positron Annihilation Lifetime Spectroscopy (PALS). In medicine they are required for diagnosis, staging, and treatment monitoring of diseases using Time-of-Flight Positron Emission Tomography (TOF-PET). In both fields time resolution is a key parameter. Sub-100 picosecond resolution is needed but not yet available. Improvement of time resolution, however, must not deteriorate other performance parameters. This project aims to overcome present physical limits. Monolithic scintillation crystals will be read out with digital photon counter (DPC) arrays coupled to each of its surfaces. Innovative data processing methods will be developed to eliminate the influence of scintillation photon propagation, currently the major bottleneck in large scintillation crystals that are nevertheless needed for high detection efficiency. We aim at coincidence resolving times (CRT) < 100ps FWHM, 10% energy resolution, 1 mm isotropic spatial resolution, and 90% detection efficiency. The detector will be incorporated in a PALS setup. After the performance has been characterized, it will be used for TU Delft’s materials research on renewable energy. The detector characterization will also serve as a proof-of-concept for application in clinical TOF-PET devices. The results are furthermore expected to be of relevance to fields such as high-energy physics. To investigate options for further improvement of the already unprecedented time resolution, studies will be done towards exploiting the Cherenkov-effect in a detector based on a hybrid Cherenkov/scintillation material.

Publications

List of publications.
year	authors and title	journal	last update
2017	S. E. Brunner, D. R. Schaart Enabling cost-effective TOF-PET by exploiting the Cherenkov emission in BGO published pages: 150, ISSN: , DOI:	Journal of Nuclear Medicine 58	2019-06-17
2017	S E Brunner, D R Schaart BGO as a hybrid scintillator / Cherenkov radiator for cost-effective time-of-flight PET published pages: 4421-4439, ISSN: 0031-9155, DOI: 10.1088/1361-6560/aa6a49	Physics in Medicine and Biology 62/11	2019-06-17
2016	S.E. Brunner, L. Gruber, A. Hirtl, K. Suzuki, J. Marton, D.R. Schaart A comprehensive characterization of the time resolution of the Philips Digital Photon Counter published pages: P11004-P11004, ISSN: 1748-0221, DOI: 10.1088/1748-0221/11/11/P11004	Journal of Instrumentation 11/11	2019-06-17
2016	Yevgen Bilevych, Stefan E. Brunner, Hong Wah Chan, Edoardo Charbon, Harry van der Graaf, Cornelis W. Hagen, Gert NÃ¼tzel, Serge D. Pinto, Violeta ProdanoviÄ‡, Daan Rotman, Fabio Santagata, Lina Sarro, Dennis R. Schaart, John Sinsheimer, John Smedley, Shuxia Tao, Anne M.M.G. Theulings Potential applications of electron emission membranes in medicine published pages: 171-174, ISSN: 0168-9002, DOI: 10.1016/j.nima.2015.10.084	Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 809	2019-06-18
2018	S. E. Brunner, Alessandro Ferri, Alberto Gola, Claudio Piemonte and Dennis R Schaart Comparative Study on the Time Resolution of Co-Doped LSO:Ce, LYSO:Ce, LFS and LGSO:Ce published pages: , ISSN: 2469-7303, DOI:	\"Prepared to be submitted to \"\"JOURNAL OF TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES\"\"\"	2019-06-18

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