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MCMQCT

Multi-functional Computational Microscopy for Quantitative Cell Tracking

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

MCMQCT project word cloud

Explore the words cloud of the MCMQCT project. It provides you a very rough idea of what is the project "MCMQCT" about.

capture integrating scientific purpose ultimately events genome assays microscope plague rates holographic locomotion influence modification resolution quantitative chip technologies evident communities environment detection computational generation unsuitable transformative dimensional cellular tool viral optical hospitals cell parasites platform biological cells drug frame microscopes diffraction microscopy gene genetic 2d environmental evolve phenotypes education view photodamage manipulation natural functionalities drugs believe water small bacteria throughput countries food effectiveness clinics tracking essentially optimized silencing purposes models performed limited

Project "MCMQCT" data sheet

The following table provides information about the project.

Coordinator	BAR ILAN UNIVERSITY Organization address address: BAR ILAN UNIVERSITY CAMPUS city: RAMAT GAN postcode: 52900 website: www.biu.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Israel [IL]
Project website	https://mcmqctblog.wordpress.com/
Total cost	263˙385 €
EC max contribution	263˙385 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2014
Funding Scheme	MSCA-IF-GF
Starting year	2015
Duration (year-month-day)	from 2015-08-01 to 2018-07-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	BAR ILAN UNIVERSITY BAR ILAN UNIVERSITY Organization address address: BAR ILAN UNIVERSITY CAMPUS city: RAMAT GAN postcode: 52900 website: www.biu.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (RAMAT GAN)	coordinator	263˙385.00
2	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Organization address address: FRANKLIN STREET 1111, 12 FLOOR city: OAKLAND CA postcode: 94607 website: http://www.universityofcalifornia.edu/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (OAKLAND CA)	partner	0.00

Map

Project objective

Quantitative assessment of cellular phenotypes can result from various processes such as genetic manipulation, gene silencing, drug application or environmental changes. In many biological processes evident development of phenotypes often requires a long-term study of the sample, which can capture events at high-resolution and high frame rates. The essential working tool for this kind of studies is the optical microscope, which is essentially limited by a small field of view of the sample in two-dimensional (2D) environment, unsuitable for the quantitative assessment of cells in a more natural environment, in which they develop and evolve within complex communities. For this task, I purpose a novel platform based on a holographic on-chip microscopy which represents a new generation of computational microscopes, by integrating transformative technologies, which will ultimately enable five-dimensional, photodamage optimized at diffraction limited resolution, quantitative cell tracking. We believe that these functionalities and the platform's cost effectiveness will enable next generation high-throughput scientific research on the influence of drugs, genome modification and environmental changes, developing new models for cell locomotion, such as viral plague growth assays performed in hospitals and clinics, detection of parasites and bacteria in food/water and for education purposes, including in developing countries.

Publications

List of publications.
year	authors and title	journal	last update
2017	Yair Rivenson, ZoltÃ¡n GÃ¶rÃ¶cs, Harun GÃ¼naydin, Yibo Zhang, Hongda Wang, Aydogan Ozcan Deep learning microscopy published pages: 1437, ISSN: 2334-2536, DOI: 10.1364/OPTICA.4.001437	Optica 4/11	2019-07-24
2016	Yair Rivenson, Yichen Wu, Hongda Wang, Yibo Zhang, Alborz Feizi, Aydogan Ozcan Sparsity-based multi-height phase recovery in holographic microscopy published pages: , ISSN: 2045-2322, DOI: 10.1038/srep37862	Scientific Reports 6/1	2019-07-24
2018	Yair Rivenson, Hatice Ceylan Koydemir, Hongda Wang, Zhensong Wei, Zhengshuang Ren, Harun GÃ¼naydÄ±n, Yibo Zhang, ZoltÃ¡n GÃ¶rÃ¶cs, Kyle Liang, Derek Tseng, Aydogan Ozcan Deep Learning Enhanced Mobile-Phone Microscopy published pages: 2354-2364, ISSN: 2330-4022, DOI: 10.1021/acsphotonics.8b00146	ACS Photonics 5/6	2019-07-24
2017	Yair Rivenson, Yibo Zhang, Harun GÃ¼naydÄ±n, Da Teng, Aydogan Ozcan Phase recovery and holographic image reconstruction using deep learning in neural networks published pages: 17141, ISSN: 2047-7538, DOI: 10.1038/lsa.2017.141	Light: Science & Applications 7/2	2019-07-24
2017	Yair Rivenson, Chris Wu, Hongda Wang, Yibo Zhang, Aydogan Ozcan High resolution computational on-chip imaging of biological samples using sparsity constraint (Conference Presentation) published pages: 100550L, ISSN: , DOI: 10.1117/12.2251765	Optics and Biophotonics in Low-Resource Settings III	2019-07-24

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The information about "MCMQCT" are provided by the European Opendata Portal: CORDIS opendata.