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VOXEL SIGNED

volumetric medical x-ray imaging at extremely low dose

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

VOXEL project word cloud

Explore the words cloud of the VOXEL project. It provides you a very rough idea of what is the project "VOXEL" about.

societal biology physical computing mathematics competitiveness camera positioned uniquely combine 3d atomic wavefront foreseeable platform basing ray avoiding transformative scientific metrology woman greatest commercialization society biological thanks medicine source computerized spatial technological cameras science imaging risk mathematical dose countries achievements extremely team physic voxel nanometre potentially water soft members integration exemplary parallel nano disciplinary physics trans succeed easiness optics prototyping afforded rotation microscope groundbreaking sensing window models tomography ct leaders relies penetration harmful underlying ultimate irradiation portugal benefit hard scientifically maximum medical resolution alternative disruptive

Project "VOXEL" data sheet

The following table provides information about the project.

Coordinator	ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO Organization address address: AVENIDA ROVISCO PAIS 1 city: LISBOA postcode: 1049 001 website: www.ist-id.pt contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Portugal [PT]
Project website	http://www.voxel-project.eu
Total cost	3˙996˙875 €
EC max contribution	3˙996˙875 € (100%)
Programme	1. H2020-EU.1.2.1. (FET Open)
Code Call	H2020-FETOPEN-2014-2015-RIA
Funding Scheme	RIA
Starting year	2015
Duration (year-month-day)	from 2015-06-01 to 2019-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO Organization address address: AVENIDA ROVISCO PAIS 1 city: LISBOA postcode: 1049 001 website: www.ist-id.pt contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PT (LISBOA)	coordinator	762˙500.00
2	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS Organization address address: RUE MICHEL ANGE 3 city: PARIS postcode: 75794 website: www.cnrs.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	846˙250.00
3	IMAGINE OPTIC IMAGINE OPTIC Organization address address: 18 RUE CHARLES DE GAULLE city: ORSAY postcode: 91400 website: www.imagine-optic.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (ORSAY)	participant	793˙125.00
4	COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES Organization address address: RUE LEBLANC 25 city: PARIS 15 postcode: 75015 website: www.cea.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS 15)	participant	510˙000.00
5	STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN Organization address address: WINTHONTLAAN 2 city: UTRECHT postcode: 3526 KV website: www.fom.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (UTRECHT)	participant	437˙500.00
6	CONSIGLIO NAZIONALE DELLE RICERCHE CONSIGLIO NAZIONALE DELLE RICERCHE Organization address address: PIAZZALE ALDO MORO 7 city: ROMA postcode: 185 website: www.cnr.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (ROMA)	participant	376˙250.00
7	UNIVERSIDAD POLITECNICA DE MADRID UNIVERSIDAD POLITECNICA DE MADRID Organization address address: CALLE RAMIRO DE MAEZTU 7 EDIFICIO RECTORADO city: MADRID postcode: 28040 website: www.upm.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	participant	271˙250.00
8	STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA Organization address address: Science Park 123 city: AMSTERDAM postcode: 1098XG website: http://www.cwi.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	0.00

Map

Project objective

Computerized Tomography (CT) has been one of the greatest achievements in medical imaging, but at the cost of a high, potentially harmful, X-ray irradiation dose. The ultimate goal of VOXEL is to provide an alternative to tomography with a disruptive technology enabling 3D X-ray imaging at very low dose. VOXEL aims at prototyping new cameras that will combine the X-ray penetration and nanometre spatial resolution, easiness to use, afforded by avoiding the rotation of the source or the sample, and extremely low dose for maximum impact on medicine and biology. VOXEL relies on the integration of trans-disciplinary fields in medical imaging, optics, X-ray physics, applied mathematics and value to society through foreseeable commercialization. VOXEL aims at prototyping in parallel a soft X-ray “water window” microscope and a hard X-ray 3D camera for medical applications. While both cameras need groundbreaking development in the underlying physics, only hard X-ray camera has high technological risk (and high societal impact). VOXEL will benefit from the soft X-ray camera thanks to its Biological applications in nano-tomography but also as a test platform for our physical and mathematical models.. The VOXEL team members are leaders in X-ray metrology, wavefront sensing, atomic physic, mathematical computing and 3D medical imaging; with VOXEL we are uniquely positioned to succeed, and to raise the competitiveness of Europe. Doing so by basing the research lead in Portugal with a woman coordinator will be exemplary: beyond the scientific and technological success, thanks to our focus in science and its valorisation, VOXEL will be transformative for scientifically emerging countries.

Deliverables

List of deliverables.
Data Management plan update	Open Research Data Pilot	2020-02-26 11:29:37
Manufacturing hard X-ray light field prototypes	Demonstrators, pilots, prototypes	2020-02-26 11:29:37
Report with the measured performances of the different X-ray optics	Documents, reports	2020-02-26 11:29:34
Optics XUV test for integration in the prototype (matrix plus enhanced lens)	Documents, reports	2020-02-26 11:29:34
Manufacturing soft X-ray light field prototypes	Demonstrators, pilots, prototypes	2020-02-26 11:29:34
Optics X-Ray test for integration in the prototype (matrix plus enhanced lens)	Documents, reports	2020-02-26 11:29:37
Report on plenoptic camera theory for X-rays	Documents, reports	2020-02-26 11:29:34
Conceptual design reports for hard X-ray light field cameras	Documents, reports	2020-02-26 11:29:33
Conceptual design reports for soft XUV light field cameras	Documents, reports	2020-02-26 11:29:33
Website with open and secured sessions	Websites, patent fillings, videos etc.	2020-02-26 11:29:34
Report with the measured performances of the different XUV optics	Documents, reports	2020-02-26 11:29:34

Take a look to the deliverables list in detail: detailed list of VOXEL deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2016	Samaan, Julien Ã‰tude et applications de l\'imagerie sans lentille par diffraction cohÃ©rente published pages: , ISSN: , DOI:	\"Optique [physics.optics]. UniversitÃ© Paris-Saclay, 2016. FranÃ§ais. ⟨NNT : 2016SACLS557⟩\" 2	2020-02-26
2017	Cassin, RÃ©my Imagerie nanomÃ©trique ultra-rapide par diffraction cohÃ©rente de rayonnement XUV produit par gÃ©nÃ©ration d\'harmoniques d\'ordre Ã©levÃ©s published pages: , ISSN: , DOI:	https://tel.archives-ouvertes.fr/tel-01664520 2	2020-02-26
2018	Lorenzo Massimi, Francesco Brun, Michela Fratini, Inna Bukreeva, Alessia Cedola An improved ring removal procedure for in-line x-ray phase contrast tomography published pages: 45007, ISSN: 1361-6560, DOI: 10.1088/1361-6560/aaa706	Physics in Medicine & Biology 63/4	2020-02-26
2016	Schumaker, W.; Brown, S.; Curry, C.; Gauthier, M.; Gamboa, E.; Goede, S.; Fletcher, L.; Kim, J.; MacDonald, M.; Mishra, R.; Roedel, C.; Glenzer, S.; Fiuza, F.; Granados, E.; Nagler, B.; Zhou, Z.; MacKinnon, A.; Obst, L.; Ziel, K.; Pak, A.; Williams, G.; Fajardo, M. Phase contrast imaging of high-intensity laser hole boring of solid-density wires at LCLS-MEC published pages: , ISSN: , DOI:		2020-02-26
2019	Joana Duarte Novel computational and experimental methods 2D and 3D soft X-ray lensless imaging published pages: , ISSN: , DOI:		2020-02-26
2018	E. Longo From X-ray tomography to the first X-ray plenoptic camera for nanoparticles bio-localization published pages: , ISSN: , DOI:		2020-02-26
2019	Lorenzo Massimi, Inna Bukreeva, Giulia Santamaria, Michela Fratini, Alessandro Corbelli, Francesco Brun, Stefano Fumagalli, Laura Maugeri, Alexandra Pacureanu, Peter Cloetens, Nicola Pieroni, Fabio Fiordaliso, Gianluigi Forloni, Antonio Uccelli, Nicole Kerlero de Rosbo, Claudia Balducci, Alessia Cedola Exploring Alzheimer\'s disease mouse brain through X-ray phase contrast tomography: From the cell to the organ published pages: 490-495, ISSN: 1053-8119, DOI: 10.1016/j.neuroimage.2018.09.044	NeuroImage 184	2020-02-26
2017	Hamed Merdji Ultrafast nanoscale imaging using high order harmonic generation (Conference Presentation) published pages: , ISSN: , DOI:		2020-02-26
2015	Merdji H. Lensless Imaging using high order harmonic generation published pages: , ISSN: , DOI:		2020-02-26
2018	Eduardo Oliva, Adrien Depresseux, Manuel Cotelo, AgustÃn Lifschitz, Fabien Tissandier, Julien Gautier, Gilles Maynard, Pedro Velarde, StÃ©phane Sebban Hydrodynamic evolution of plasma waveguides for soft-x-ray amplifiers published pages: , ISSN: 2470-0045, DOI: 10.1103/physreve.97.023203	Physical Review E 97/2	2020-02-26
2018	Philippe Zeitoun; Domenico Alj; Hugo Dacasa; Ombeline de La Rochefoucauld Compact metrology beamline for EUV optic and test of adaptive optic published pages: , ISSN: , DOI:		2020-02-26
2019	Gareth O. Williams, H.-K. Chung, S. KÃ¼nzel, V. Hilbert, U. Zastrau, H. Scott, S. Daboussi, B. Iwan, A. I. Gonzalez, W. Boutu, H. J. Lee, B. Nagler, E. Granados, 8 E. Galtier, P. Heimann, B. Barbrel, R. W. Lee, B. I. Cho, P. Renaudin, H. Merdji, Ph. Zeitoun, M. Fajardo The impact of free electron degeneracy on collisional rates in plasmas published pages: , ISSN: , DOI:		2020-02-26
2019	Williams, Gareth O.; Chung, H. -K.; KÃ¼nzel, S.; Hilbert, V.; Zastrau, U.; Scott, H.; Daboussi, S.; Iwan, B.; Gonzalez, A. I.; Boutu, W.; Lee, H. J.; Nagler, B.; Granados, E.; Galtier, 8 E.; Heimann, P.; Barbrel, B.; Lee, R. W.; Cho, B. I.; Renaudin, P.; Merdji, H.; Zeitoun, Ph.; Fajardo, M. The impact of free electron degeneracy on collisional rates in plasmas published pages: , ISSN: , DOI:	3	2020-02-26
2019	Maddalena Mastrogiacomo, Gaetano Campi, Ranieri Cancedda, Alessia Cedola Synchrotron radiation techniques boost the research in bone tissue engineering published pages: 33-46, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2019.03.031	Acta Biomaterialia 89	2020-02-26
2018	Laura Maugeri, Mauro DiNuzzo, Marta Moraschi, Charles Nicaise, Inna Bukreeva, Fabio Mangini, Federico Giove, Alessia Cedola, Michela Fratini Fractal Dimension Analysis of High-Resolution X-Ray Phase Contrast Micro-Tomography Images at Different Threshold Levels in a Mouse Spinal Cord published pages: 48, ISSN: 2410-3896, DOI: 10.3390/condmat3040048	Condensed Matter 3/4	2020-02-26
2016	Merdji H. 2D and 3D nanoscale imaging using high order harmonic generation published pages: , ISSN: , DOI:		2020-02-26
2017	RÃ©my Cassin Ultrafast lensless imaging and applicationsÂ published pages: , ISSN: , DOI:		2020-02-26
2018	Liping Shi, Rana Nicolas, Jose R. C. Andrade, Willem Boutu, Dominik Franz, Torsten Heidenblut, Carsten Reinhardt, Uwe Morgner, Hamed Merdji, Milutin Kovacev Impact of Plasmon-Induced Atoms Migration in Harmonic Generation published pages: 1208-1214, ISSN: 2330-4022, DOI: 10.1021/acsphotonics.7b01560	ACS Photonics 5/4	2020-02-26
2019	Michele Natile Pulse compression and CEP stabilization of Ytterbium fiber laser: application to high harmonic generation published pages: , ISSN: , DOI:		2020-02-26
2017	S. Kunzel Characterization, optimization and applications of coherent XUV sources published pages: , ISSN: , DOI:		2020-02-26
2018	Nicola ViganÃ², Henri Der Sarkissian, Charlotte Herzog, Ombeline de la Rochefoucauld, Robert van Liere, Kees Joost Batenburg Tomographic approach for the quantitative scene reconstruction from light field images published pages: 22574, ISSN: 1094-4087, DOI: 10.1364/oe.26.022574	Optics Express 26/18	2020-02-26
2018	Q.â€‰Y. van den Berg, E.â€‰V. Fernandez-Tello, T. Burian, J. ChalupskÃ½, H.-K Chung, O. Ciricosta, G.â€‰L. Dakovski, V. HÃ¡jkovÃ¡, P. Hollebon, L. Juha, J. Krzywinski, R.â€‰W. Lee, M.â€‰P. Minitti, T.â€‰R. Preston, A.â€‰G. de la Varga, V. Vozda, U. Zastrau, J.â€‰S. Wark, P. Velarde, S.â€‰M. Vinko Clocking Femtosecond Collisional Dynamics via Resonant X-Ray Spectroscopy published pages: , ISSN: 0031-9007, DOI: 10.1103/physrevlett.120.055002	Physical Review Letters 120/5	2020-02-26
2017	Merdji H Nanoplasmonic amplification of laser harmonics published pages: , ISSN: , DOI:		2020-02-26
2018	P. Estrela X-Ray Optics published pages: , ISSN: , DOI:		2020-02-26
2018	N. ViganÃ², W. Ludwig Advances in 6d diffraction contrast tomography published pages: C04017-C04017, ISSN: 1748-0221, DOI: 10.1088/1748-0221/13/04/C04017	Journal of Instrumentation 13/04	2020-02-26
2019	Ramona Corman Table-top lensless imaging applications in biology published pages: , ISSN: , DOI:		2020-02-26
2015	Gareth O. Williams, A. I. Gonzalez, S. KÃ¼nzel, L. Li, M. Lozano, E. Oliva, B. Iwan, S. Daboussi, W. Boutu, H. Merdji, M. Fajardo, Ph. Zeitoun Fourier transform holography with high harmonic spectra for attosecond imaging applications published pages: 3205, ISSN: 0146-9592, DOI: 10.1364/ol.40.003205	Optics Letters 40/13	2020-02-26
2015	Boutu W Imaging dynamics with (sub-)femtosecond and nanometer resolutions published pages: , ISSN: , DOI:		2020-02-26
2019	Domingo GarcÃa-Senz, Pedro Velarde, Francisco Suzuki-Vidal, Chantal StehlÃ©, Manuel Cotelo, David Portillo, Tomasz Plewa, Arthur Pak Interaction of Hemispherical Blast Waves with Inhomogeneous Spheres: Probing the Collision of a Supernova Ejecta with a Nearby Companion Star in the Laboratory published pages: 177, ISSN: 1538-4357, DOI: 10.3847/1538-4357/aaf894	The Astrophysical Journal 871/2	2020-02-26
2018	Marta Fajardo, Richard Dendy 44th European physical society conference on plasma physics published pages: 10101, ISSN: 0741-3335, DOI: 10.1088/1361-6587/aa9775	Plasma Physics and Controlled Fusion 60/1	2020-02-26
2015	Merdji H. 3D nanoscale lensless imaging using high harmonic generation published pages: , ISSN: , DOI:		2020-02-26
2017	Merdji H. Nanoscale single view 3D imaging based on hybrid phase retrieval and in-line holography imaging published pages: , ISSN: , DOI:		2020-02-26
2019	J. Duarte, R. Cassin, J. Huijts, B. Iwan, F. Fortuna, L. Delbecq, H. Chapman, M. Fajardo, M. Kovacev, W. Boutu, H. Merdji Computed stereo lensless X-ray imaging published pages: 449-453, ISSN: 1749-4885, DOI: 10.1038/s41566-019-0419-1	Nature Photonics 13/7	2020-02-26
2017	Cassin, ReÌmy Imagerie nanomÃ©trique ultra-rapide par diffraction cohÃ©rente de rayonnement XUV produit par gÃ©nÃ©ration d\'harmoniques d\'ordre Ã©levÃ©s published pages: , ISSN: , DOI:	\"Physique des Hautes Energies - ExpÃ©rience [hep-ex]. UniversitÃ© Paris-Saclay, 2017. FranÃ§ais. 〈NNT : 2017SACLS591〉\" 2	2020-02-26
2016	Julien Samaan Prototyping a lenless microscopeÂ published pages: , ISSN: , DOI:		2020-02-26
2018	G. Williams X-ray based plasma diagnostics published pages: , ISSN: , DOI:		2020-02-26
2018	J. Koliyadu Spatio-temporal characterization of high harmonic generation for plasma diagnostics published pages: , ISSN: , DOI:		2020-02-26
2018	E. Stefanutti, A. Sierra, P. Miocchi, L. Massimi, F. Brun, L. Maugeri, I. Bukreeva, A. Nurmi, G. Begani Provinciali, G. Tromba, O. GrÃ¶hn, F. Giove, A. Cedola, M. Fratini Assessment of the effects of different sample perfusion procedures on phase-contrast tomographic images of mouse spinal cord published pages: C03027-C03027, ISSN: 1748-0221, DOI: 10.1088/1748-0221/13/03/C03027	Journal of Instrumentation 13/03	2020-02-26
2015	Boutu W, Ducousso M, Hergott JF, Merdji H HHG high flux sources published pages: , ISSN: , DOI:	Optical Technologies for Extreme-Ultraviolet and Soft X-ray Coherent Sources	2020-02-26
2018	G. Williams, M. Fajardo The impact of free electron degeneracy on collisional rates in plasmas published pages: , ISSN: , DOI:		2020-02-26
2018	Julius Huijts Attosecond lensless imaging published pages: , ISSN: , DOI:		2020-02-26
2019	Nicola ViganÃ², Pablo MartÃnez Gil, Charlotte Herzog, Ombeline de la Rochefoucauld, Robert van Liere, Kees Joost Batenburg Advanced light-field refocusing through tomographic modeling of the photographed scene published pages: 7834, ISSN: 1094-4087, DOI: 10.1364/oe.27.007834	Optics Express 27/6	2020-02-26
2016	I. Bukreeva, A. Mittone, A. Bravin, G. Festa, M. Alessandrelli, P. Coan, V. Formoso, R. G. Agostino, M. Giocondo, F. Ciuchi, M. Fratini, L. Massimi, A. Lamarra, C. Andreani, R. Bartolino, G. Gigli, G. Ranocchia, A. Cedola Virtual unrolling and deciphering of Herculaneum papyri by X-ray phase-contrast tomography published pages: 27227, ISSN: 2045-2322, DOI: 10.1038/srep27227	Scientific Reports 6	2020-02-26

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