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HYPMED SIGNED

Digital Hybrid Breast PET/MRI for Enhanced Diagnosis of Breast Cancer

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

HYPMED project word cloud

Explore the words cloud of the HYPMED project. It provides you a very rough idea of what is the project "HYPMED" about.

demand insert cancer body pet fails therapy structural combined decision multidisciplinary breast tailoring tracers introduce rf surface pave prediction transparent unprecedented carefully minimal diagnosis socio innovative detector death biopsy mr tool clinical ultra hypmed women regular channel invasive ct characterisation issue data correlated paradigm turned commercialization guided biomarkers imaging shift patients guide industry successful frequently 250 prostate sensitivity mri hybrid functional resolution economic employs smes cardiac therapies once coil designed lack scientists mere integrate engineering monitoring digital pivotal select molecular inserts treatment expand detection appropriate

Project "HYPMED" data sheet

The following table provides information about the project.

Coordinator	EIBIR GEMEINNUTZIGE GMBH ZUR FORDERUNG DER ERFORSCHUNG DER BIOMEDIZINISCHEN BILDGEBUNG Organization address address: NEUTORGASSE 9/2 city: WIEN postcode: 1010 website: www.eibir.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Austria [AT]
Project website	http://www.hypmed.eu
Total cost	5˙861˙957 €
EC max contribution	5˙861˙957 € (100%)
Programme	1. H2020-EU.3.1.3. (Treating and managing disease)
Code Call	H2020-PHC-2015-two-stage
Funding Scheme	RIA
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2022-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	EIBIR GEMEINNUTZIGE GMBH ZUR FORDERUNG DER ERFORSCHUNG DER BIOMEDIZINISCHEN BILDGEBUNG EIBIR GEMEINNUTZIGE GMBH ZUR FORDERUNG DER ERFORSCHUNG DER BIOMEDIZINISCHEN BILDGEBUNG Organization address address: NEUTORGASSE 9/2 city: WIEN postcode: 1010 website: www.eibir.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (WIEN)	coordinator	394˙637.00
2	UNIVERSITAETSKLINIKUM AACHEN UNIVERSITAETSKLINIKUM AACHEN Organization address address: Pauwelsstrasse 30 city: AACHEN postcode: 52074 website: www.ukaachen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (AACHEN)	participant	1˙971˙303.00
3	FUTURA COMPOSITES BV FUTURA COMPOSITES BV Organization address address: MARCONISTRAAT 40 city: HEERHUGOWAARD postcode: 1704 RG website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (HEERHUGOWAARD)	participant	1˙132˙100.00
4	TECHNISCHE UNIVERSITEIT DELFT TECHNISCHE UNIVERSITEIT DELFT Organization address address: STEVINWEG 1 city: DELFT postcode: 2628 CN website: www.tudelft.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (DELFT)	participant	967˙770.00
5	NORAS MRI PRODUCTS GMBH NORAS MRI PRODUCTS GMBH Organization address address: LEIBNIZSTRASSE 4 city: HOCHBERG postcode: 97204 website: www.noras.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (HOCHBERG)	participant	595˙875.00
6	MEDIZINISCHE UNIVERSITAET WIEN MEDIZINISCHE UNIVERSITAET WIEN Organization address address: SPITALGASSE 23 city: WIEN postcode: 1090 website: www.meduniwien.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (WIEN)	participant	297˙875.00
7	PHILIPS ELECTRONICS NEDERLAND BV PHILIPS ELECTRONICS NEDERLAND BV Organization address address: HIGH TECH CAMPUS 52 city: EINDHOVEN postcode: 5656 AG website: www.philips.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (EINDHOVEN)	participant	275˙303.00
8	INTRASENSE INTRASENSE Organization address address: 1231 AVENUE DU MONDIAL 98 city: MONTPELLIER postcode: 34000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (MONTPELLIER)	participant	117˙967.00
9	WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER Organization address address: SCHLOSSPLATZ 2 city: MUENSTER postcode: 48149 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUENSTER)	participant	106˙625.00
10	FORSCHUNGSZENTRUM JULICH GMBH FORSCHUNGSZENTRUM JULICH GMBH Organization address address: WILHELM JOHNEN STRASSE city: JULICH postcode: 52428 website: www.fz-juelich.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (JULICH)	participant	2˙500.00

Map

Project objective

Breast cancer represents a leading cause of cancer death in women and a major socio-economic issue. With currently available methods, early diagnosis frequently fails. Moreover, beyond mere detection, there is an ever-increasing need for improved non-invasive characterisation of cancer. Targeted therapies require an in-depth analysis of cancer to select and guide appropriate treatment. Both, PET and MRI can provide molecular and functional information that may be of pivotal importance for tailoring therapy. However, current whole-body PET/MRI systems lack the necessary sensitivity and resolution for this task. HYPMED addresses this by engineering an innovative imaging tool. HYPMED will integrate an innovative fully-digital MRI-transparent PET-detector into a novel multi-channel PET-transparent MRI surface coil. The PET-RF insert will allow unprecedented imaging of breast cancer with high-resolution/ultra-high sensitivity PET, combined with high-level structural and functional MRI, and allow minimal-invasive MR- and PET-guided targeted biopsy. Moreover with such PET-RF inserts, every regular clinical MR-system can, upon demand, be turned into a hybrid system. We will evaluate the impact of this technology on breast cancer diagnosis, prediction, and monitoring/assessment of treatment response by a carefully designed clinical study that employs established and novel PET tracers in 250 patients. Imaging data will be correlated with established and novel molecular biomarkers; results will be compared to those obtained from whole-body PET/MRI and PET/CT. A multidisciplinary consortium of clinical scientists, 3 SMEs and an industry partner will pave the way for commercialization of HYPMED products for advanced clinical decision making in cancer patients. Once HYPMED is successful, we will expand this approach to other applications such as prostate cancer or cardiac hybrid imaging, and thus introduce a paradigm shift in the field of PET/MR hybrid imaging as a whole.

Deliverables

List of deliverables.
Project Website and CI	Websites, patent fillings, videos etc.	2020-04-07 20:24:44

Take a look to the deliverables list in detail: detailed list of HYPMED deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Michelle Zhang, Joao V. Horvat, Blanca Bernard-Davila, Maria Adele Marino, Doris Leithner, R. Elena Ochoa-Albiztegui, Thomas H. Helbich, Elizabeth A. Morris, Sunitha Thakur, Katja Pinker Multiparametric MRI model with dynamic contrast-enhanced and diffusion-weighted imaging enables breast cancer diagnosis with high accuracy published pages: 864-874, ISSN: 1053-1807, DOI: 10.1002/jmri.26285	Journal of Magnetic Resonance Imaging 49/3	2020-04-07
2018	Nicolas Gross-Weege, Thomas Dey, Pierre Gebhardt, David Schug, Bjoern Weissler, Volkmar Schulz Characterization methods for comprehensive evaluations of shielding materials used in an MRI published pages: 1415-1424, ISSN: 0094-2405, DOI: 10.1002/mp.12762	Medical Physics 45/4	2020-04-07
2018	Andreas Stadlbauer, Max Zimmermann, Barbara Bennani-Baiti, Thomas H. Helbich, Pascal Baltzer, Paola Clauser, Panagiotis Kapetas, Zsuzsanna Bago-Horvath, Katja Pinker Development of a Non-invasive Assessment of Hypoxia and Neovascularization with Magnetic Resonance Imaging in Benign and Malignant Breast Tumors: Initial Results published pages: , ISSN: 1536-1632, DOI: 10.1007/s11307-018-1298-4	Molecular Imaging and Biology	2020-04-07

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The information about "HYPMED" are provided by the European Opendata Portal: CORDIS opendata.