CHEM2NATURE
Enabling precision chemical methodologies applied to natural-based systems for the development of multifunctional biomedical devices
Total Cost €
0EC-Contrib. €
0Partnership
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Project "CHEM2NATURE" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSIDADE DO MINHO
Organization address contact info |
| Coordinator Country | Portugal [PT] |
| Project website | http://chem2nature.eu/ |
| Total cost | 1˙007˙453 € |
| EC max contribution | 1˙007˙453 € (100%) |
| Programme |
1. H2020-EU.4.b. (Twinning of research institutions) |
| Code Call | H2020-TWINN-2015 |
| Funding Scheme | CSA |
| Starting year | 2016 |
| Duration (year-month-day) | from 2016-01-01 to 2018-12-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSIDADE DO MINHO | PT (BRAGA) | coordinator | 539˙993.00 |
| 2 | UNIVERSIDADE DE AVEIRO | PT (AVEIRO) | participant | 203˙717.00 |
| 3 | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE | CH (LAUSANNE) | participant | 134˙496.00 |
| 4 | THE UNIVERSITY OF WARWICK | UK (COVENTRY) | participant | 129˙246.00 |
| 5 | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY | KR (DAEJEON) | participant | 0.00 |
Map
Project objective
CHEM2NATURE addresses current limitations of UMINHO in the Chemistry field regarding its scientific know-how and partnerships with world-leading institutions. UMINHO seeks to improve the multifunctionality of natural-origin polymers, often with limited bioactivity and stimuli-responsiveness, and increase the performance of cell-based therapies. Introducing such properties by precision chemical modifications would allow the development of added-value products with instructive and adaptive properties for cellular response control, drug delivery and diagnosis. The main goal of CHEM2NATURE is to combat UMINHO’s limited knowledge, expertise and experience on advanced chemical routes for biopolymer, biomaterials and “living” surface modification. To this aim, an international training and scientific network will be established to accelerate the generation of technologies amenable to be used in the production of innovative healthcare devices. The capability of UMINHO to train highly-qualified researchers and staff would greatly increase, giving rise to a new generation of specialized professionals with scientific/translational competence. The consortium will comprise UMINHO, UAVR and 3 international competitive institutions in Chemistry: 2 European and 1 Asian. The latter will improve UMINHO’s know-how in the translational/clinical fields and raise opportunities to establish new contacts with high-performing and Emerging Asian countries. CHEM2NATURE proposes the joint organisation of events and short-term exchange of senior researchers and staff, aiming at training actions and execution of scientific work in the scope of ongoing scientific projects. Outputs include the increase of number and quality of scientific publications, intellectual property and regional-to-national economic development. CHEM2NATURE will endorse the establishment of a long-lasting consortium beyond the project timeframe for the preparation of new scientific projects and research lines in UMINHO.
Deliverables
| D5.5 Scientific publications in international peer-reviewed scientific journals (Month 24) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:41 |
| D5.3 Open days sessions to the general public (Month 24) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:41 |
| D4.1 Request for a special issue in an ISI-indexed international journal – “Engineering and chemical principles in cells encapsulation†(Month 36) | Other | 2019-09-09 14:57:41 |
| D5.4 Press releases, project brochures, newsletters and web magazines (Month 36) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:41 |
| D3.1 Request for a special issue in an ISI-indexed international journal – “Precision chemical modification of surfaces†(Month 24) | Other | 2019-09-09 14:57:41 |
| D5.2 Project website and collaborative network establishment (Month 4) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:39 |
| D5.3 Open days sessions to the general public (Month 12) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:39 |
| D5.5 Scientific publications in international peer-reviewed scientific journals (Month 12) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:39 |
| D5.4 Press releases, project brochures, newsletters and web magazines (Month 12) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:39 |
| D2.1 Request for a special issue in an ISI-indexed international journal – “Chemical strategies for the modification of natural origin materials†(Month 11) | Other | 2019-09-09 14:57:39 |
| D5.1 Publications record of the coordinator organisation on the Participant Portal (Month 2) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:39 |
| D5.5 Scientific publications in international peer-reviewed scientific journals (Month 36) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:41 |
| D5.7 Book on “advanced chemical modifications on natural systems†(Month 36) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:41 |
| D5.6 Patent filling (Month 30) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:41 |
| D5.4 Press releases, project brochures, newsletters and web magazines (Month 24) | Websites, patent fillings, videos etc. | 2019-09-09 14:57:41 |
Take a look to the deliverables list in detail: detailed list of CHEM2NATURE deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2018 |
Sara Amorim, Diana Soares da Costa, Daniela Freitas, Celso A. Reis, Rui L. Reis, Iva Pashkuleva, Ricardo A. Pires Molecular weight of surface immobilized hyaluronic acid influences CD44-mediated binding of gastric cancer cells published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-34445-0 |
Scientific Reports 8/1 | 2019-09-09 |
| 2017 |
Carla Silva, Agatha Carretero, Diana Soares da Costa, Rui L. Reis, Ramon Novoa-Carballal, Iva Pashkuleva Design of protein delivery systems by mimicking extracellular mechanisms for protection of growth factors published pages: 283-293, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2017.08.042 |
Acta Biomaterialia 63 | 2019-09-09 |
| 2018 |
Olesia Dudik, Isabel Leonor, Joana R. Xavier, Hans Tore Rapp, Ricardo A. Pires, Tiago H. Silva, Rui L. Reis Sponge-derived silica for tissue regeneration published pages: 577-578, ISSN: 1369-7021, DOI: 10.1016/j.mattod.2018.03.025 |
Materials Today 21/5 | 2019-09-09 |
| 2018 |
Ramon Novoa-Carballal, Agatha Carretero, Raul Pacheco, Rui L. Reis, Iva Pashkuleva Star-Like Glycosaminoglycans with Superior Bioactivity Assemble with Proteins into Microfibers published pages: 14341-14345, ISSN: 0947-6539, DOI: 10.1002/chem.201802243 |
Chemistry - A European Journal 24/54 | 2019-09-09 |
| 2018 |
Rui R. Costa, Miguel González-Pérez, Marcos Herrero-Gutiérrez, Ricardo A. Pires, Matilde Alonso, J. Carlos Rodriguez-Cabello, Rui L. Reis, Iva Pashkuleva Tuning the Stiffness of Surfaces by Assembling Genetically Engineered Polypeptides with Tailored Amino Acid Sequence published pages: 3401-3411, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.8b00723 |
Biomacromolecules 19/8 | 2019-09-09 |
| 2017 |
Rami Mhanna, Jana Becher, Matthias Schnabelrauch, Rui L. Reis, Iva Pashkuleva Sulfated Alginate as a Mimic of Sulfated Glycosaminoglycans: Binding of Growth Factors and Effect on Stem Cell Behavior published pages: 1700043, ISSN: 2366-7478, DOI: 10.1002/adbi.201700043 |
Advanced Biosystems 1/7 | 2019-09-09 |
| 2017 |
João S. Fernandes, Piergiorgio Gentile, Ricardo A. Pires, Rui L. Reis, Paul V. Hatton Multifunctional bioactive glass and glass-ceramic biomaterials with antibacterial properties for repair and regeneration of bone tissue published pages: 2-11, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2017.06.046 |
Acta Biomaterialia 59 | 2019-09-09 |
| 2018 |
Ana M. Carvalho, Raquel Teixeira, Ramón Novoa-Carballal, Ricardo A. Pires, Rui L. Reis, Iva Pashkuleva Redox-Responsive Micellar Nanoparticles from Glycosaminoglycans for CD44 Targeted Drug Delivery published pages: 2991-2999, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.8b00561 |
Biomacromolecules 19/7 | 2019-09-09 |
| 2018 |
Bárbara B. Mendes, Manuel Gómez-Florit, Ricardo A. Pires, Rui M. A. Domingues, Rui L. Reis, Manuela E. Gomes Human-based fibrillar nanocomposite hydrogels as bioinstructive matrices to tune stem cell behavior published pages: 17388-17401, ISSN: 2040-3364, DOI: 10.1039/c8nr04273j |
Nanoscale 10/36 | 2019-09-09 |
| 2017 |
A. Carretero, D. Soares da Costa, R. L. Reis, I. Pashkuleva Extracellular matrix-inspired assembly of glycosaminoglycan–collagen fibers published pages: 3103-3106, ISSN: 2050-7518, DOI: 10.1039/C7TB00704C |
J. Mater. Chem. B 5/17 | 2019-09-09 |
| 2017 |
João Borges, Maria P. Sousa, Goksu Cinar, Sofia G. Caridade, Mustafa O. Guler, João F. Mano Nanoengineering Hybrid Supramolecular Multilayered Biomaterials Using Polysaccharides and Self-Assembling Peptide Amphiphiles published pages: 1605122, ISSN: 1616-301X, DOI: 10.1002/adfm.201605122 |
Advanced Functional Materials 27/17 | 2019-09-09 |
| 2017 |
Ivo M. Aroso, Ana R. Araújo, Ricardo A. Pires, Rui L. Reis Cork: Current Technological Developments and Future Perspectives for this Natural, Renewable, and Sustainable Material published pages: 11130-11146, ISSN: 2168-0485, DOI: 10.1021/acssuschemeng.7b00751 |
ACS Sustainable Chemistry & Engineering 5/12 | 2019-09-09 |
| 2019 |
Alexandra Brito, Yousef M. Abul-Haija, Diana Soares da Costa, Ramon Novoa-Carballal, Rui L. Reis, Rein V. Ulijn, Ricardo A. Pires, Iva Pashkuleva Minimalistic supramolecular proteoglycan mimics by co-assembly of aromatic peptide and carbohydrate amphiphiles published pages: 2385-2390, ISSN: 2041-6520, DOI: 10.1039/c8sc04361b |
Chemical Science 10/8 | 2019-09-09 |
| 2017 |
A. Carretero, D. Soares da Costa, R. L. Reis, I. Pashkuleva Extracellular matrix-inspired assembly of glycosaminoglycan–collagen fibers published pages: 3103-3106, ISSN: 2050-7518, DOI: 10.1039/C7TB00704C |
J. Mater. Chem. B 5/17 | 2019-09-09 |
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