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CRADL SIGNED

Continuous Regional Analysis Device for neonate Lung

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

CRADL project word cloud

Explore the words cloud of the CRADL project. It provides you a very rough idea of what is the project "CRADL" about.

regional detected protocols tool immaturity mortality free born inexpensive daily children reducing adulthood population ventilation supportive chronic radiation disease preterm mechanical effectiveness delivering radiative infants risk each dynamic bedside prematurely inflation electrical tools efficacy aeration interventions causes safety ing babies invasive syndrome vulnerable lung impedance adverse lack plays collapse pulmonary urgently eit breathing tomography monitoring clinical disability suffer function survival cradl final treatment shown respiratory 15 paediatric million provides heterogeneity distress universally guiding populat injury lasting care technique morbidity continuous imaging time reduce bronchiolitis acute deaths severe of

Project "CRADL" data sheet

The following table provides information about the project.

Coordinator	MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION Organization address address: THE BURROUGHS, HENDON . city: LONDON postcode: NW4 4BT website: http://www.mdx.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://cradlproject.org/
Total cost	5˙537˙142 €
EC max contribution	4˙234˙330 € (76%)
Programme	1. H2020-EU.3.1.3. (Treating and managing disease)
Code Call	H2020-PHC-2015-two-stage
Funding Scheme	RIA
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2019-06-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION Organization address address: THE BURROUGHS, HENDON . city: LONDON postcode: NW4 4BT website: http://www.mdx.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	coordinator	997˙500.00
2	UNIVERSITY COLLEGE LONDON UNIVERSITY COLLEGE LONDON Organization address address: GOWER STREET city: LONDON postcode: WC1E 6BT website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	1˙067˙302.00
3	STUDIO FIFIELD SRL STUDIO FIFIELD SRL Organization address address: VIA PIETRO COLLETTA 69 city: MILANO postcode: 20137 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	584˙062.00
4	CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL Organization address address: OLSHAUSENSTRASSE 40 city: KIEL postcode: 24118 website: http://www.uni-kiel.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (KIEL)	participant	514˙690.00
5	LINNEUNIVERSITETET LINNEUNIVERSITETET Organization address address: LINNAEUS UNIVERSITY city: VAXJO postcode: 35195 website: www.lnu.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (VAXJO)	participant	355˙025.00
6	ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM Organization address address: MEIBERGDREEF 15 city: AMSTERDAM postcode: 1105AZ website: www.amc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	323˙750.00
7	FILANTHROPIKO IDRYMA VIOIATRIKON EREVNON FILANTHROPIKO IDRYMA VIOIATRIKON EREVNON Organization address address: PO BOX 24039 city: LEFKOSIA postcode: 1700 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CY (LEFKOSIA)	participant	162˙500.00
8	Ministry of Health of the Republic of Cyprus Ministry of Health of the Republic of Cyprus Organization address address: 1 Prodromou Street & 17 Chilonos Street 1 & 17 city: Nicosia postcode: 1448 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CY (Nicosia)	participant	137˙500.00
9	PANAXEA BV PANAXEA BV Organization address address: SCIENCE PARK 400 MATRIX II UNIT 3.1 city: AMSTERDAM postcode: 1098 XH website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	92˙000.00
10	SENTEC AG SENTEC AG Organization address address: RINGSTRASSE 39 city: THERWIL postcode: 4106 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (THERWIL)	participant	0.00
11	SWISSTOM AG SWISSTOM AG Organization address address: SCHULSTRASSE 1 city: LANDQUART postcode: 7302 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (LANDQUART)	participant	0.00
12	UNIVERSITE DE GENEVE UNIVERSITE DE GENEVE Organization address address: RUE DU GENERAL DUFOUR 24 city: GENEVE postcode: 1211 website: www.unige.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (GENEVE)	participant	0.00

Map

Project objective

Each year 15 million babies are born prematurely and many suffer from respiratory failure due to immaturity of the lung and lack of control of breathing. Although respiratory support, especially mechanical ventilation, can improve their survival, it also causes severe injury to the vulnerable lung resulting in severe and chronic pulmonary morbidity lasting in to adulthood. Heterogeneity of lung aeration, resulting in areas of lung over inflation and lung collapse, plays a crucial part in the risk of mortality and morbidity due to respiratory failure. This distribution of lung aeration cannot be detected by currently available bedside monitoring tools and imaging methods. Thus, an imaging technique for continuous non-invasive bedside monitoring of infants lung function is urgently needed. In order to address this, CRADL will use EIT technology to establish a monitoring tool for interventions in the paediatric population. Electrical impedance tomography (EIT) is a non-radiative, inexpensive technique that can facilitate real time dynamic monitoring of lung aeration, and recent studies have shown that it is effective in monitoring aeration in preterm babies. CRADL will show how EIT can provide new cost effective, easy to use, respiratory management tools and clinical protocols that can be universally adopted to reduce deaths and disability in preterm babies by delivering a tool that provides continuous, non-invasive, radiation free, bedside information on regional lung aeration and ventilation during daily clinical care of (preterm) infants and children with respiratory failure. CRADL will also assess the effectiveness, efficacy and safety of such a system in guiding respiratory management and supportive care of the most common causes of paediatric respiratory failure (respiratory distress syndrome, bronchiolitis and acute respiratory distress syndrome), with the final goal of reducing short and long term adverse effects of disease and its treatment in this populat

Deliverables

List of deliverables.
Validation of ability of EIT monitoring to detect adverse pulmonary effects associated with high ventilation heterogeneity	Documents, reports	2019-10-15 13:17:15
Increased user base of this technology	Other	2019-10-15 13:17:16
Wearable jacket with new microelectronic chips	Demonstrators, pilots, prototypes	2019-10-15 13:17:19
Contributions to EIT and EIDORS websites	Websites, patent fillings, videos etc.	2019-10-15 13:17:20
Optimised interface design for clinical users	Other	2019-10-15 13:17:13
Clinical users trained in the application of current Swisscom clinical system and the pediatric version containing improvements made by the project.	Websites, patent fillings, videos etc.	2019-10-15 13:17:18
Website creation	Websites, patent fillings, videos etc.	2019-08-06 19:07:22

Take a look to the deliverables list in detail: detailed list of CRADL deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2017	Yu Wu, Dai Jiang, Andy Bardill, Serena De Gelidi, Richard Bayford, Andreas Demosthenous Live Demonstration: A Wearable EIT System Using Active Electrodes for Monitoring Respiration published pages: , ISSN: , DOI: 10.5281/zenodo.557093		2019-08-06
2017	Serena de Gelidi, Andy Bardill, Yu Wu, Andreas Demosthenous, Andrew Tizzard, Richard Bayford Torso shape detection to improve lung monitoring published pages: , ISSN: , DOI:		2019-08-06
2016	Richard Bayford, Andrew Tizzard, InÃ©z Frerichs, Norbert Weiler, Christina Karaoli, Stelios Christofides, Charalambos Yiannakkaras, Peter Rimensberger, Sven Nordebo, Stephan H. BÃ¶hm, Anton van Kaam, Bruce Fifield, Christopher Knox, Lotte Steuten, Gimon de Graaf, Rebecca Yerworth, Micheal Butterworth, Andreas Demosthenous Continuous Regional Analysis Device for Neonatal Lung (CRADL) published pages: 172-172, ISSN: , DOI: 10.1007/978-3-319-32703-7_35		2019-08-06
2017	D. Khodadad, S. Nordebo, N. Seifnaraghi, A. Waldmann, B. Muller, R. Bayford Breath detection using short-time Fourier transform analysis in Electrical Impedance Tomography published pages: 2185-2187, ISSN: , DOI:	32nd URSI General Assembly & Scientific Symposium	2019-08-06
2017	Yerworth RJ, Bayford R DICOM for EIT presentation at the 18th International Conference on Biomedical Applications of Electrical Impedance Tomography published pages: , ISSN: , DOI:		2019-08-06
2019	A Shiraz, D Khodadad, S Nordebo, R Yerworth, I Frerichs, A van Kaam, M Kallio, T Papadouri, R Bayford, A Demosthenous Compressive sensing in electrical impedance tomography for breathing monitoring published pages: 34010, ISSN: 1361-6579, DOI: 10.1088/1361-6579/ab0daa	Physiological Measurement 40/3	2019-08-06
2019	Marika Rahtu, InÃ©z Frerichs, Andreas D Waldmann, Claas Strodthoff, Tobias Becher, Richard Bayford, Merja Kallio Early Recognition of Pneumothorax in Neonatal RDS with Electrical Impedance Tomography published pages: , ISSN: 1073-449X, DOI: 10.1164/rccm.201810-1999im	American Journal of Respiratory and Critical Care Medicine	2019-08-06
2018	Nima Seifnaraghi, Andrew Tizzard, Serena de Gelidi, Davood Khodadad, Sven Nordebo, Anton van Kaam, InÃ©z Frerichs, Andreas Waldmann, Erich Sorantin, Sebastian Tschauner, Andreas Demosthenous, Richard Bayford Effect of Thorax Deformation during Neonatal Lung EIT published pages: , ISSN: , DOI:		2019-08-06
2017	Nima Seifnaraghi ,Andrew Tizzard, Serena de Gelidi, Davood Khodadad, Sven Nordebo, Anton Van Kaam, Inez Frerichs, Andreas Waldmann, Erich Sorantin, Sebastian Tschauner, Andreas Demosthenous, Stelios Christofides, Richard Bayford Estimation of Thorax Shape for Forward Modelling in Lungs EIT published pages: , ISSN: , DOI:		2019-08-06
2018	C Strodthoff Effect of suctioning on chest EIT findings in neonates: preliminary results of a multicentre clinical study published pages: , ISSN: , DOI:		2019-08-06
2019	Inez Frerichs Electrical impedance tomography for monitoring regional lung ventilation in critically ill patients. published pages: , ISSN: , DOI:		2019-08-06
2019	A. DuprÃ©, M-R. Benissa, B. MÃ¼ller, A. D. Waldmann, R. Yerworth, T. Becher, M. Miedema, S. Nordebo, D. Khodadad, I. Frerichs, R. Bayford, P. C. Rimensberger Graphical user interface for patient data overview of long and continuous EIT monitoring for research analysis published pages: , ISSN: , DOI:		2019-08-06
2018	Sven Nordebo, Mariana Dalarsson, Davood Khodadad, Beat MÃ¼ller, Andreas D Waldmann, Tobias Becher, Inez Frerichs, Louiza Sophocleous, Daniel SjÃ¶berg, Nima Seifnaraghi, Richard Bayford A parametric model for the changes in the complex valued conductivity of a lung during tidal breathing published pages: 205401, ISSN: 0022-3727, DOI: 10.1088/1361-6463/aabc04	Journal of Physics D: Applied Physics 51/20	2019-08-06
2016	InÃ©z Frerichs, Marcelo B P Amato, Anton H van Kaam, David G Tingay, Zhanqi Zhao, BartÅ‚omiej Grychtol, Marc Bodenstein, HervÃ© Gagnon, Stephan H BÃ¶hm, Eckhard Teschner, Ola Stenqvist, Tommaso Mauri, Vinicius Torsani, Luigi Camporota, Andreas Schibler, Gerhard K Wolf, Diederik Gommers, Steffen Leonhardt, Andy Adler Chest electrical impedance tomography examination, data analysis, terminology, clinical use and recommendations: consensus statement of the TRanslational EIT developmeNt stuDy group published pages: 83-93, ISSN: 0040-6376, DOI: 10.1136/thoraxjnl-2016-208357	Thorax 72/1	2019-08-06
2019	Inez Frerichs Electrical impedance tomography: The past, the present and the future. published pages: , ISSN: , DOI:		2019-08-06
2019	David G. Tingay, Andreas D. Waldmann, InÃ©z Frerichs, Sarath Ranganathan, Andy Adler Electrical Impedance Tomography Can Identify Ventilation and Perfusion Defects: A Neonatal Case published pages: 384-386, ISSN: 1073-449X, DOI: 10.1164/rccm.201808-1551le	American Journal of Respiratory and Critical Care Medicine 199/3	2019-08-06
2018	S de Gelidi, N Seifnaraghi, A Bardill, A Tizzard, Y Wu, E Sorantin, S Nordebo, A Demosthenous, R Bayford Torso shape detection to improve lung monitoring published pages: 74001, ISSN: 1361-6579, DOI: 10.1088/1361-6579/aacc1c	Physiological Measurement 39/7	2019-08-06
2019	Inez Frerichs, Tobias Becher Chest electrical impedance tomography measures in neonatology and paediatrics â€“ a survey on clinical usefulness published pages: , ISSN: 0967-3334, DOI: 10.1088/1361-6579/ab1946	Physiological Measurement	2019-08-06
2018	Tobias Becher and InÃ©z Frerichs Clinical acceptance of various EIT parameters in neonatology and paediatrics: A systematic assessment of cliniciansÂ´ opinions published pages: , ISSN: , DOI: 10.5281/zenodo.1210247		2019-08-06
2016	Y. Wu, P. Langlois, R. Bayford and A. Demosthenous A novel active electrode IC for wearable EIT system published pages: , ISSN: , DOI: 10.5281/zenodo.55753		2019-08-06
2018	Yu Wu, Dai Jiang, Andy Bardill, Serena de Gelidi, Richard Bayford, Andreas Demosthenous A High Frame Rate Wearable EIT System Using Active Electrode ASICs for Lung Respiration and Heart Rate Monitoring published pages: 3810-3820, ISSN: 1549-8328, DOI: 10.1109/tcsi.2018.2858148	IEEE Transactions on Circuits and Systems I: Regular Papers 65/11	2019-08-06
2018	Serena de Gelidi, Andy Bardill, Nima Seifnaraghi, Yu Wu, InÃ©z Frerichs, Andreas Demosthenous, Andrew Tizzard, Richard Bayford Towards a thoracic conductive phantom for EIT published pages: , ISSN: , DOI:		2019-08-06
2018	D Khodadad, S Nordebo, B MÃ¼ller, A Waldmann, R Yerworth, T Becher, I Frerichs, L Sophocleous, A van Kaam, M Miedema, N Seifnaraghi, R Bayford Optimized breath detection algorithm in electrical impedance tomography published pages: 94001, ISSN: 1361-6579, DOI: 10.1088/1361-6579/aad7e6	Physiological Measurement 39/9	2019-08-06
2018	Marika Rahtu, Andreas D Waldmann, Esa Rahtu, Tobias Becher, InÃ©z Frerichs, Richard Bayford, Merja Kallio Changes in ventilation distribution from pressure controlled ventilation to neutrally adjusted ventilator assist published pages: , ISSN: , DOI:		2019-08-06
2018	L Sophocleous, I Frerichs, M Miedema, M Kallio, T Papadouri, C Karaoli, T Becher, D G Tingay, A H van Kaam, R Bayford, A D Waldmann Clinical performance of a novel textile interface for neonatal chest electrical impedance tomography published pages: 44004, ISSN: 1361-6579, DOI: 10.1088/1361-6579/aab513	Physiological Measurement 39/4	2019-08-06

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