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MediHealth SIGNED

Novel natural products for healthy ageing from Mediterranean diet and food plants of other global sources

Total Cost €

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EC-Contrib. €

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Partnership

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Outcomes and
results

MediHealth project word cloud

Explore the words cloud of the MediHealth project. It provides you a very rough idea of what is the project "MediHealth" about.

plant analytical food optimization healthy metabolism tc agents synthesis plants successful cell supplements ageing comprise considerably active interactive industry global lasting platform synergies techniques diet generating vivo area base innovation rationally complementary carry nutraceuticals pharmacological introduce researcher orientation assays stage extended metabolites performed isolation countries silico profiling evaluation medihealth transferred flies efficient training benefits academia identification levels sources vitro bioactive dietary universities special innovative mediterranean interests competences mutual embrace discovery core aspires skills valuable seconded mice natural scientific expertise scheme public sectors balanced model models multidisciplinary complimentary environments subjected secondments constituents enterprises

Project "MediHealth" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITAET INNSBRUCK Organization address address: INNRAIN 52 city: INNSBRUCK postcode: 6020 website: http://www.uibk.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Austria [AT]
Project website	http://medihealth.eu/
Total cost	1˙224˙000 €
EC max contribution	1˙224˙000 € (100%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2015
Funding Scheme	MSCA-RISE
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2019-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITAET INNSBRUCK UNIVERSITAET INNSBRUCK Organization address address: INNRAIN 52 city: INNSBRUCK postcode: 6020 website: http://www.uibk.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (INNSBRUCK)	coordinator	288˙000.00
2	ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON Organization address address: 6 CHRISTOU LADA STR city: ATHINA postcode: 10561 website: www.elke.uoa.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHINA)	participant	292˙500.00
3	UNIVERSITE DE GENEVE UNIVERSITE DE GENEVE Organization address address: RUE DU GENERAL DUFOUR 24 city: GENEVE postcode: 1211 website: www.unige.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (GENEVE)	participant	153˙000.00
4	UNIVERSITEIT ANTWERPEN UNIVERSITEIT ANTWERPEN Organization address address: PRINSSTRAAT 13 city: ANTWERPEN postcode: 2000 website: www.ua.ac.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (ANTWERPEN)	participant	130˙500.00
5	EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Organization address address: Raemistrasse 101 city: ZUERICH postcode: 8092 website: https://www.ethz.ch/de.html contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (ZUERICH)	participant	103˙500.00
6	GALENICA FARMAKEFTIKI VIDMICHANIA ANONYMOS ETAIRIA GALENICA FARMAKEFTIKI VIDMICHANIA ANONYMOS ETAIRIA Organization address address: ELEFTHERIAS 4 city: KIFISIA postcode: 14564 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (KIFISIA)	participant	90˙000.00
7	ROUSSELET CENTRIFUGATION SA ROUSSELET CENTRIFUGATION SA Organization address address: AVENUE RHIN ET DANUBE 45 city: ANNONAY postcode: 7100 website: www.rousselet-robatel.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (ANNONAY)	participant	90˙000.00
8	BIONORICA RESEARCH GMBH BIONORICA RESEARCH GMBH Organization address address: MITTERWEG 24 city: INNSBRUCK postcode: 6020 website: www.bionorica.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (INNSBRUCK)	participant	58˙500.00
9	VIVACELL BIOTECHNOLOGY GMBH VIVACELL BIOTECHNOLOGY GMBH Organization address address: FERDINAND PORSCHE STRASSE 5 city: DENZLINGEN postcode: 79211 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (DENZLINGEN)	participant	18˙000.00
10	FACULTE DES SCIENCES DE SFAX FACULTE DES SCIENCES DE SFAX Organization address address: ROUTE DE SOUKRA KM 3,5 city: SFAX postcode: 3000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	TN (SFAX)	partner	0.00
11	TRUONG DAI HOC Y DUOC TP.HCM TRUONG DAI HOC Y DUOC TP.HCM Organization address address: HONG BANG STREET 217 DISTRICT 5 OLD STREET NAME AN DUONG VUONG ST city: HO CHI MINH CITY postcode: - website: http://www.yds.edu.vn contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	VN (HO CHI MINH CITY)	partner	0.00
12	TSHWANE UNIVERSITY OF TECHNOLOGY TSHWANE UNIVERSITY OF TECHNOLOGY Organization address address: 5TH FLOOR BUILDING 21 STAATSARTILLE ROAD city: PRETORIA postcode: 82 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ZA (PRETORIA)	partner	0.00
13	UNIVERSIDAD CATOLICA DEL NORTE UNIVERSIDAD CATOLICA DEL NORTE Organization address address: AVENIDA ANGAMOS 0610 city: ANTOFAGASTA postcode: n.a. website: www.ucn.cl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CL (ANTOFAGASTA)	partner	0.00

Map

Project objective

The main goal of the MediHealth project is to introduce a novel approach for the discovery of active agents of food plants from Mediterranean diet and other global sources to promote healthy ageing. This will be achieved through an extended and well-balanced scheme of researcher’s secondments between 5 universities and 4 enterprises from EU & Associated countries as well as 4 universities from Third countries. A mutual scientific project developed on the needs and interests of both sectors exploiting the existing complementary expertise will be the base of this proposal. Plants from the Mediterranean diet and food plants from TC will be rationally selected and will be subjected to an integrated, interactive and comprehensive platform including in silico, in vitro (advanced cell-based assays), in vivo (flies and mice models) & metabolism assessment. Advanced analytical techniques will embrace the pharmacological evaluation process for the efficient isolation and identification of bioactive plant constituents. Pharmacological profiling of bioactive natural products as well as identification and synthesis of their metabolites will be carried out. Finally, to carry to the stage of development innovative products in the area of nutraceuticals/dietary supplements process-optimization studies will be performed. Within this project, core scientific multidisciplinary knowledge from different research areas will be integrated creating valuable synergies. Expertise will be transferred by means of the seconded researchers training in environments with different research orientation where complimentary skills are required. Special attention will be given to dissemination activities aiming to public awareness of benefits of healthy diet(s). MediHealth aspires to comprise a successful model promoting considerably researchers’ competences and long-lasting collaboration between Industry and Academia generating innovation potential at the European and global levels.

Deliverables

List of deliverables.
Establishment of a website	Websites, patent fillings, videos etc.	2020-02-12 09:16:01

Take a look to the deliverables list in detail: detailed list of MediHealth deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2018	Waltenberger B., Adamopoulos N., Allouche N., Fiebich B., Halabalaki M., Heinke R., Jansen-DÃ¼rr P., Kesternich V., Pieters L., Queiroz E.F., SchÃ¶nbichler S., Schwaiger S., Skaltsounis A.-L., Tran H., Trougakos I.P., Viljoen A., Wolfender J.-L., Wolfrum C., Xynos N., Stuppner H. Novel natural products for healthy ageing from Mediterranean diet and food plants of other global sources - the MediHealth project published pages: , ISSN: , DOI:	PHYTO Valley - First Austrian Summit on Natural Products	2020-02-13
2019	B Waltenberger, N Adamopoulos, N Allouche, B Fiebich, M Halabalaki, P Jansen-DÃ¼rr, V Kesternich, L Pieters, S SchÃ¶nbichler, LA Skaltsounis, H Tran, IP Trougakos, A Viljoen, J-L Wolfender, C Wolfrum, N Xynos, H Stuppner MediHealth â€“ an interdisciplinary and international research and innovation staff exchange project to identify novel natural products for healthy ageing published pages: 1572, ISSN: , DOI: 10.1055/s-0039-3400404	67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP 85(18)	2020-02-13
2018	Nora S. Engels, Birgit Waltenberger, Barbara Michalak, Loi Huynh, Hung Tran, Anna K. Kiss, Hermann Stuppner Inhibition of Pro-Inflammatory Functions of Human Neutrophils by Constituents of Melodorum fruticosum Leaves published pages: e1800269, ISSN: 1612-1872, DOI: 10.1002/cbdv.201800269	Chemistry & Biodiversity 15/11	2020-02-13
2018	Dimitrios Stagos, Dimitrios Balabanos, Salomi Savva, Zoi Skaperda, Alexandros Priftis, Efthalia Kerasioti, Eleni V. Mikropoulou, Konstantina Vougogiannopoulou, Sofia Mitakou, Maria Halabalaki, Demetrios Kouretas Extracts from the Mediterranean Food Plants Carthamus lanatus , Cichorium intybus , and Cichorium spinosum Enhanced GSH Levels and Increased Nrf2 Expression in Human Endothelial Cells published pages: 1-14, ISSN: 1942-0900, DOI: 10.1155/2018/6594101	Oxidative Medicine and Cellular Longevity 2018	2020-02-13
2018	Sophia Wedel, Maria Manola, Maria Cavinato, Ioannis Trougakos, Pidder Jansen-DÃ¼rr Targeting Protein Quality Control Mechanisms by Natural Products to Promote Healthy Ageing published pages: 1219, ISSN: 1420-3049, DOI: 10.3390/molecules23051219	Molecules 23/5	2020-02-13
2018	Eleni Mikropoulou, Konstantina Vougogiannopoulou, Eleftherios Kalpoutzakis, Aimilia Sklirou, Zoi Skaperda, JoÃ«lle Houriet, Jean-Luc Wolfender, Ioannis Trougakos, Dimitrios Kouretas, Maria Halabalaki, Sofia Mitakou Phytochemical Composition of the Decoctions of Greek Edible Greens (ChÃ³rta) and Evaluation of Antioxidant and Cytotoxic Properties published pages: 1541, ISSN: 1420-3049, DOI: 10.3390/molecules23071541	Molecules 23/7	2020-02-13
2018	Waltenberger, Birgit; Halabalaki, Maria; Schwaiger, Stefan; Adamopoulos, Nicolas; Allouche, Noureddine; Fiebich, Bernd L; Hermans, Nina; Jansen-DÃ¼rr, Pidder; Kesternich, Victor; Pieters, Luc; SchÃ¶nbichler, Stefan; Skaltsounis, Alexios-Leandros; Tran, Hung; Trougakos, Ioannis P; Viljoen, Alvaro; Wolfender, Jean-Luc; Wolfrum, Christian; Xynos, Nikos; Stuppner, Hermann Novel Natural Products for Healthy Ageing from the Mediterranean Diet and Food Plants of Other Global Sourcesâ€”The MediHealth Project published pages: 1097, ISSN: 1420-3049, DOI: 10.3929/ethz-b-000277279	Molecules 23(5)	2020-02-13
2017	Sentiljana Gumeni, Zoi Evangelakou, Vassilis Gorgoulis, Ioannis Trougakos Proteome Stability as a Key Factor of Genome Integrity published pages: 2036, ISSN: 1422-0067, DOI: 10.3390/ijms18102036	International Journal of Molecular Sciences 18/10	2020-02-13
2019	EV Mikropoulou, Z Evangelakou, M Manola, S Gumeni, IP Trougakos, LA Skaltsounis, M Halabalaki A holistic UPLC-HRMS-based approach exploring the phytochemistry, bioactivity and metabolome impact of Cichorium spinosumâ€™ s decoction in Drosophila melanogaster published pages: , ISSN: , DOI: 10.1055/s-0039-3399823	67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP	2020-02-13
2019	ME Sakavitsi, A Breynaert, A Angelis, L Pieters, N Hermans, S Mitakou, M Halabalaki Simulating Human Gastrointestinal and colonic biotransformation pathways through and in vitro assay reveals insight on hydroxytyrosol and oleuropein metabolism published pages: , ISSN: , DOI:	Young Researchers Workshop GA 2019	2020-02-13
2016	Vincent Brieudes, Apostolis Angelis, Konstantina Vougogiannopoulou, Harris Pratsinis, Dimitris Kletsas, Sofia Mitakou, Maria Halabalaki, Leandros Skaltsounis Phytochemical Analysis and Antioxidant Potential of the Phytonutrient-Rich Decoction of Cichorium spinosum and C. intybus published pages: 1070-1078, ISSN: 0032-0943, DOI: 10.1055/s-0042-107472	Planta Medica 82/11/12	2020-02-12
2017	Ioannis P. Trougakos Proteostasis network deregulation as a main molecular link of ageing and carcinogenesis published pages: , ISSN: , DOI:	39th ANNUAL CONFERENCE OF THE HELLENIC SOCIETY FOR BIOLOGICAL SCIENCES Proceedings Lecture	2020-02-12
2017	ME Sakavitsi, Z Evangelakou, A FaÃºndez Catherine, G Lemus Belen Ringele, A Argyropoulou, V Kesternich, I Trougakos, M Halabalaki, A Skaltsounis Leandros Phytochemical investigation of the Chilean berries Aristotelia chilensis and Ugni molinae. Evaluation of their anti-ageing effects employing a Drosophila model. published pages: , ISSN: , DOI: 10.1055/s-0037-1608278	65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017)	2020-02-12
2018	Eleni N. Tsakiri, Sentiljana Gumeni, Kalliopi K. Iliaki, Dimitra Benaki, Konstantinos Vougas, Gerasimos P. Sykiotis, Vassilis G. Gorgoulis, Emmanuel Mikros, Luca Scorrano and Ioannis P. Trougakos Nrf2 as a main hub in the wiring of proteostatic, mitostatic and metabolic pathways published pages: , ISSN: , DOI:	COST Action BM1307 PROTEOSTASIS, Proteostatic Mechanisms in Health & Disease Proceedings Oral Presentation	2020-02-12
2017	Ioannis P. Trougakos Nrf2 as a central hub in the wiring of proteostatic, mitostatic and metabolic pathways published pages: 12, ISSN: , DOI:	68th Panhellenic Congress of the Greek Biochemical and Molecular Biology Society Proceedings Lecture 14	2020-02-12
2017	N Mncwangi, B Waltenberger, G Baraldo, P Jansen-DÃ¼rr, A Viljoen, H Stuppner Sclerocarya birrea cortex ethanolic extract â€“ Chemical characterisation and NOX4 inhibition (anti-ageing property) published pages: , ISSN: , DOI: 10.1055/s-0037-1608258	65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017)	2020-02-12
2017	Maria-Eleni Sakavitsi, Zoi Evangelakou, Gabriela Belen Lemus Ringele, Amal Ghorbel, Aikaterini Argyropoulou, Victor Kesternich, Noureddine Allouche, Ioannis Trougakos, Maria Halabalaki, Leandros Skaltsounis EXPLORATION OF DIETARY PLANTS FROM WORLDWIDE BIODIVERSITY AIMING THE DISCOVERY OF ACTIVE AGENTS WITH ANTI-AGEING EFFECTS published pages: 20, ISSN: , DOI:	Proceedings PP192	2020-02-12

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The information about "MEDIHEALTH" are provided by the European Opendata Portal: CORDIS opendata.

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