Explore the words cloud of the Autocat project. It provides you a very rough idea of what is the project "Autocat" about.
The following table provides information about the project.
Coordinator |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Organization address contact info |
Coordinator Country | United Kingdom [UK] |
Total cost | 2˙278˙073 € |
EC max contribution | 2˙278˙073 € (100%) |
Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
Code Call | ERC-2015-CoG |
Funding Scheme | ERC-COG |
Starting year | 2016 |
Duration (year-month-day) | from 2016-05-01 to 2021-04-30 |
Take a look of project's partnership.
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1 | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD | UK (OXFORD) | coordinator | 2˙278˙073.00 |
'The origin of life is not well understood, and is one of the great remaining questions in science. Autocatalytic chemical reactions have been extensively studied with the aim of providing insight into the principles underlying living systems. In biology, organisms can be thought of as imperfect self-replicators, which produce closely related species, allowing for selection and evolution. Autocatalysis is also an important part of many other biological processes. This project aims to develop new autocatalytic reactions where two simple chemical building blocks come together to give a more complex product, and then the product aggregates to give primitive cell-like structures or 'protocells' such as micelles or vesicles. The protocells allow the starting materials to mix more efficiently, speeding up the reaction in time and giving rise to complex behaviour of the protocells. These reactions will serve as models that I hope will contribute to understanding how cell-like systems can emerge from simpler chemicals and be relevant to how life started on earth. This project will give the opportunity to study chemical systems that may be able to evolve in time, allow development of useful chemical models of important biological processes, and provide ‘bottom-up’ approaches to synthetic biology. This research will potential allow the study evolution in a new ways, develop technology useful to a number of scientific fields, and potentially shed light on the processes that allowed chemistry to become biology on the primitive Earth.'
year | authors and title | journal | last update |
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2018 |
Ignacio Colomer, Sarah M. Morrow, Stephen P. Fletcher A transient self-assembling self-replicator published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-04670-2 |
Nature Communications 9/1 | 2019-04-18 |
2016 |
Jaime Ortega-Arroyo, Andrew J. Bissette, Philipp Kukura, Stephen P. Fletcher Visualization of the spontaneous emergence of a complex, dynamic, and autocatalytic system published pages: 11122-11126, ISSN: 0027-8424, DOI: 10.1073/pnas.1602363113 |
Proceedings of the National Academy of Sciences 113/40 | 2019-04-18 |
2017 |
Sarah M. Morrow, Andrew J. Bissette, Stephen P. Fletcher Potential for minimal self-replicating systems in a dynamic combinatorial library of equilibrating imines published pages: 5005-5010, ISSN: 0040-4020, DOI: 10.1016/j.tet.2017.06.045 |
Tetrahedron 73/33 | 2019-04-18 |
2018 |
Elias A. J. Post, Andrew J. Bissette, Stephen P. Fletcher Self-reproducing micelles coupled to a secondary catalyst published pages: 8777-8780, ISSN: 1359-7345, DOI: 10.1039/c8cc02136h |
Chemical Communications 54/63 | 2019-04-18 |
2019 |
Sarah M. Morrow, Ignacio Colomer, Stephen P. Fletcher A chemically fuelled self-replicator published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-019-08885-9 |
Nature Communications 10/1 | 2019-04-18 |
2019 |
Elias A. J. Post, Stephen P. Fletcher Controlling the Kinetics of Self-Reproducing Micelles by Catalyst Compartmentalization in a Biphasic System published pages: 2741-2755, ISSN: 0022-3263, DOI: 10.1021/acs.joc.8b03149 |
The Journal of Organic Chemistry 84/5 | 2019-04-18 |
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The information about "AUTOCAT" are provided by the European Opendata Portal: CORDIS opendata.