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Multi-SIP Hydrogel

A multifunctional self-immolative hydrogel for accelerating the healing of chronic wounds

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

Multi-SIP Hydrogel project word cloud

Explore the words cloud of the Multi-SIP Hydrogel project. It provides you a very rough idea of what is the project "Multi-SIP Hydrogel" about.

immolative species sequential cutting stimulus self medicine designed components chronic polymer wound plan biochemical scope types ki responsive biomaterials me broad karolinska supervision accelerate undergo therapeutic division world proof hydrogel vitro independent once science stevens action preparing entitled degrade chemistry biology modular curie undertaken fellowship engineering tissue sip multifunctional regeneration platform synthetic odowska regenerative molly designing sk expertise stimuli degradation cell initiate hydrogels career multiple edge marie contain proliferation matched reactive skin payload oxygen prof wounds enzymatic

Project "Multi-SIP Hydrogel" data sheet

The following table provides information about the project.

Coordinator	KAROLINSKA INSTITUTET Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 website: www.ki.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Sweden [SE]
Project website	https://bit.ly/2JngaDF
Total cost	173˙857 €
EC max contribution	173˙857 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2015
Funding Scheme	MSCA-IF-EF-ST
Starting year	2017
Duration (year-month-day)	from 2017-02-01 to 2019-01-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	KAROLINSKA INSTITUTET KAROLINSKA INSTITUTET Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 website: www.ki.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (STOCKHOLM)	coordinator	173˙857.00

Map

Project objective

'In this Marie SkÅ‚odowska-Curie Fellowship project entitled “Multi-SIP Hydrogel” I will design a modular synthetic platform for preparing multifunctional self-immolative polymer (SIP) hydrogels designed to accelerate tissue regeneration in chronic skin wounds. The hydrogels will contain multiple SIP components, each designed to rapidly degrade and deliver a therapeutic payload in response to a specific biochemical stimulus typical of a chronic wound (e.g., reactive oxygen species or enzymatic action). During the two years of this Fellowship, I aim to establish a proof-of-principle SIP-hydrogel system that will undergo sequential stimuli-responsive degradation and promote cell proliferation in vitro. This Fellowship will be undertaken under the supervision of Prof. Molly Stevens in the Division of Biomaterials and Regenerative Medicine at the Karolinska Institute (KI), which has the world-leading expertise in polymer chemistry, biomaterials engineering, cell biology and tissue engineering crucial to the objectives of the proposed work plan. Due to the modular design of the 'Multi-SIP Hydrogel' platform, there is broad scope for designing SIP-hydrogels matched to different tissue types once a proof-of-principle is established. This will initiate new research areas at the cutting edge of biomaterials science, which will help me to establish my own independent research career following the proposed Fellowship.'

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The information about "MULTI-SIP HYDROGEL" are provided by the European Opendata Portal: CORDIS opendata.