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SEQUOIA-DD

Boosting productivity and performance in drug discovery with SEQUOIA - Semantic Query of Information Assets

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

SEQUOIA-DD project word cloud

Explore the words cloud of the SEQUOIA-DD project. It provides you a very rough idea of what is the project "SEQUOIA-DD" about.

validate platform extended times uk prioritised semantic gt prototype time synapse data market transfer internal sequoia environments strategic drug model commercial datasets code spreadsheet web stakeholders core environment rare urgently cancers disparate plan lack initiation kernel billion engagement query initiate chain correlations regulatory catalyse entry productivity drugs seek online software treat gain fulfil rates neurological trials discovery probe free financial proved public 5 reactions pharmaceutical solution semantically feasibility industry question ip building causal ontologies barrier final silos 100 compatibility business timescales roadmaps performance optimise roadmap assets disrupt compliance elaborated huge supply sectors diseases strategy

Project "SEQUOIA-DD" data sheet

The following table provides information about the project.

Coordinator	SYNAPSE INFORMATION LIMITED Organization address address: 33 LUDGATE HILL city: BIRMINGHAM postcode: B3 1EH website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://www.synapseinformation.com/
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT)) 2. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
Code Call	H2020-SMEINST-1-2016-2017
Funding Scheme	SME-1
Starting year	2016
Duration (year-month-day)	from 2016-09-01 to 2017-02-28

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	SYNAPSE INFORMATION LIMITED SYNAPSE INFORMATION LIMITED Organization address address: 33 LUDGATE HILL city: BIRMINGHAM postcode: B3 1EH website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (BIRMINGHAM)	coordinator	50˙000.00

Map

Project objective

Synapse Information (UK) have developed a novel semantic web technology, SEQUOIA – Semantic Query of Information Assets – allowing users to rapidly question > 100 disparate data assets in a code-free spreadsheet environment. Having proved the core platform functionality within the financial sector, Synapse now seek to apply SEQUOIA to the field of drug discovery R&D.

New drugs are required urgently to treat cancers & other rare/neurological diseases. However, costs and timescales of drug development are huge due to high failure rates. A principle barrier is the lack of real time comparison of disparate datasets, which can identify causal correlations behind reactions throughout the R&D process. Building on the prototype kernel solution, SEQUOIA targets the many high performance silos of public online drug R&D data, enabling all researchers to semantically probe these ontologies against internal R&D. Synapse therefore aim to catalyse a strategic 10 - 100× productivity gain during the discovery phase to disrupt the €5.5 billion/yr drug discovery software market.

The overall project aims to: fulfil the further technical developments required to transfer SEQUOIA into priority sectors within drug R&D; initiate the technical and commercial partnerships with key stakeholders in the pharmaceutical industry; validate performance through extended field trials; establish regulatory compliance; deliver compatibility with key user data environments; and optimise a developed product.

The proposed Phase 1 feasibility study seeks to address these requirements through: delivery of an elaborated business plan; prioritised EU market entry strategy; analysis of market-held data assets, technical development roadmap; engagement of key stakeholders in the pharmaceutical industry; supply chain initiation; development of IP strategy and value model; as well as regulatory and legal roadmaps for the final phase of developments and exploitation.

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The information about "SEQUOIA-DD" are provided by the European Opendata Portal: CORDIS opendata.