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SYSCID SIGNED

A Systems medicine approach to chronic inflammatory disease

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

SYSCID project word cloud

Explore the words cloud of the SYSCID project. It provides you a very rough idea of what is the project "SYSCID" about.

arthritis variome stable core code levels lupus map indications builds groups comprise outcome editing types epigenome therapies defects generation twinsuk tool models molecular setup risk deconvolution prediction single therapeutic therapy transcriptome layers guide alterations icgc diseases temporal infrastructure stratification data software retrospective gut disease individual cells prospective shared cohorts systemic temporally independent 15 inflammatory immune rheumatoid microbiome algorithmic bowel human meta cid resolution reprogramming biological basis decisions snp purified biomarkers overlap macrophages validate epigenetic medicine cell cd14 polarization clinical macrophage cd8 hit validation ihec predictive variation blood tools solid lymphocytes alleviate joined causative initial fundamental methylome trials employs erythematodes signatures identification syscid cd4 patient innovative sme

Project "SYSCID" data sheet

The following table provides information about the project.

Coordinator	CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL Organization address address: OLSHAUSENSTRASSE 40 city: KIEL postcode: 24118 website: http://www.uni-kiel.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Project website	http://www.syscid.eu
Total cost	16˙018˙111 €
EC max contribution	14˙456˙236 € (90%)
Programme	1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
Code Call	H2020-SC1-2016-RTD
Funding Scheme	RIA
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2022-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL Organization address address: OLSHAUSENSTRASSE 40 city: KIEL postcode: 24118 website: http://www.uni-kiel.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (KIEL)	coordinator	2˙854˙260.00
2	RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN Organization address address: REGINA PACIS WEG 3 city: BONN postcode: 53113 website: www.uni-bonn.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BONN)	participant	1˙259˙351.00
3	VIB VZW VIB VZW Organization address address: RIJVISSCHESTRAAT 120 city: ZWIJNAARDE - GENT postcode: 9052 website: www.vib.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (ZWIJNAARDE - GENT)	participant	1˙181˙518.00
4	UNIVERSITAT DES SAARLANDES UNIVERSITAT DES SAARLANDES Organization address address: CAMPUS city: SAARBRUCKEN postcode: 66123 website: www.uni-saarland.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (SAARBRUCKEN)	participant	1˙173˙675.00
5	UNIVERSITE DU LUXEMBOURG UNIVERSITE DU LUXEMBOURG Organization address address: 2 AVENUE DE L'UNIVERSITE city: ESCH-SUR-ALZETTE postcode: 4365 website: http://wwwen.uni.lu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	LU (ESCH-SUR-ALZETTE)	participant	1˙115˙040.00
6	THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE Organization address address: TRINITY LANE THE OLD SCHOOLS city: CAMBRIDGE postcode: CB2 1TN website: www.cam.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (CAMBRIDGE)	participant	1˙061˙022.00
7	UNIVERSITE DE LIEGE UNIVERSITE DE LIEGE Organization address address: PLACE DU 20 AOUT 7 city: LIEGE postcode: 4000 website: www.ulg.ac.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LIEGE)	participant	1˙016˙900.00
8	KING'S COLLEGE LONDON KING'S COLLEGE LONDON Organization address address: STRAND city: LONDON postcode: WC2R 2LS website: www.kcl.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	919˙083.00
9	GENOS DOO ZA VJESTACENJE I ANALIZU GENOS DOO ZA VJESTACENJE I ANALIZU Organization address address: VATROGASNA 112 city: OSIJEK postcode: 31000 website: www.genos.hr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	HR (OSIJEK)	participant	880˙050.00
10	EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH Organization address address: HEINRICH-HERTZ-ALLEE 1 city: ST INGBERT postcode: 66386 website: www.eurice.eu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (ST INGBERT)	participant	657˙022.00
11	IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON Organization address address: SORANOU EFESIOU 4 city: ATHINA postcode: 115 27 website: www.bioacademy.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHINA)	participant	604˙227.00
12	SYDDANSK UNIVERSITET SYDDANSK UNIVERSITET Organization address address: CAMPUSVEJ 55 city: ODENSE M postcode: 5230 website: www.sdu.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (ODENSE M)	participant	590˙935.00
13	HUMANITAS UNIVERSITY HUMANITAS UNIVERSITY Organization address address: VIA RITA LEVI MONTALCINI SNC city: PIEVE EMANUELE postcode: 20090 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (PIEVE EMANUELE)	participant	411˙026.00
14	ISTITUTO EUROPEO DI ONCOLOGIA SRL ISTITUTO EUROPEO DI ONCOLOGIA SRL Organization address address: Via Filodrammatici 10 city: MILANO postcode: 20121 website: www.ieo.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	383˙998.00
15	COMMA SOFT AG COMMA SOFT AG Organization address address: PUTZCHENS CHAUSSEE 202-204A city: BONN postcode: 53229 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BONN)	participant	348˙125.00
16	UNIVERSITE DE GENEVE UNIVERSITE DE GENEVE Organization address address: RUE DU GENERAL DUFOUR 24 city: GENEVE postcode: 1211 website: www.unige.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (GENEVE)	participant	0.00

Map

Project objective

'The SYSCID consortium aims to develop a systems medicine approach for disease prediction in CID. We will focus on three major CID indications with distinct characteristics, yet a large overlap of their molecular risk map: inflammatory bowel disease, systemic lupus erythematodes and rheumatoid arthritis. We have joined 15 partners from major cohorts and initiatives in Europe (e.g.IHEC, ICGC, TwinsUK and Meta-HIT) to investigate human data sets on three major levels of resolution: whole blood signatures, signatures from purified immune cell types (with a focus on CD14 and CD4/CD8) and selected single cell level analyses. Principle data layers will comprise SNP variome, methylome, transcriptome and gut microbiome. SYSCID employs a dedicated data management infrastructure, strong algorithmic development groups (including an SME for exploitation of innovative software tools for data deconvolution) and will validate results in independent retrospective and prospective clinical cohorts. Using this setup we will focus on three fundamental aims : (i) the identification of shared and unique 'core disease signatures” which are associated with the disease state and independent of temporal variation, (ii) the generation of 'predictive models of disease outcome'- builds on previous work that pathways/biomarkers for disease outcome are distinct from initial disease risk and may be shared across diseases to guide therapy decisions on an individual patient basis, (iii) 'reprogramming disease'- will identify and target temporally stable epigenetic alterations in macrophages and lymphocytes in epigenome editing approaches as biological validation and potential novel therapeutic tool . Thus, SYSCID will foster the development of solid biomarkers and models as stratification in future long-term systems medicine clinical trials but also investigate new causative therapies by editing the epigenome code in specific immune cells, e.g. to alleviate macrophage polarization defects.'

Deliverables

List of deliverables.
Public project website	Websites, patent fillings, videos etc.	2020-04-08 14:24:38

Take a look to the deliverables list in detail: detailed list of SYSCID deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Nikolaos I Panousis, George K Bertsias, Halit Ongen, Irini Gergianaki, Maria G Tektonidou, Maria Trachana, Luciana Romano-Palumbo, Deborah Bielser, Cedric Howald, Cristina Pamfil, Antonis Fanouriakis, Despoina Kosmara, Argyro Repa, Prodromos Sidiropoulos, Emmanouil T Dermitzakis, Dimitrios T Boumpas Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity published pages: 1079-1089, ISSN: 0003-4967, DOI: 10.1136/annrheumdis-2018-214379	Annals of the Rheumatic Diseases 78/8	2020-04-08
2019	Dionysis Nikolopoulos, Antonis Fanouriakis, Dimitrios T. Boumpas Update on the pathogenesis of central nervous system lupus published pages: 669-677, ISSN: 1040-8711, DOI: 10.1097/bor.0000000000000655	Current Opinion in Rheumatology 31/6	2020-04-08
2019	Goran JosipoviÄ‡, Vanja TadiÄ‡, Marija KlasiÄ‡, Vladimir Zanki, Ivona BeÄeheli, Felicia Chung, Akram Ghantous, Toma Keser, Josip MaduniÄ‡, Maria BoÅ¡koviÄ‡, Gordan Lauc, Zdenko Herceg, Aleksandar Vojta, Vlatka ZoldoÅ¡ Antagonistic and synergistic epigenetic modulation using orthologous CRISPR/dCas9-based modular system published pages: 9637-9657, ISSN: 0305-1048, DOI: 10.1093/nar/gkz709	Nucleic Acids Research 47/18	2020-04-08
2019	Mohamad Jawhara, Signe Bek SÃ¸rensen, Berit Lilienthal Heitmann, Vibeke Andersen Biomarkers of Whole-Grain and Cereal-Fiber Intake in Human Studies: A Systematic Review of the Available Evidence and Perspectives published pages: 2994, ISSN: 2072-6643, DOI: 10.3390/nu11122994	Nutrients 11/12	2020-04-08
2019	R. J. M. Bashford-Rogers, L. Bergamaschi, E. F. McKinney, D. C. Pombal, F. Mescia, J. C. Lee, D. C. Thomas, S. M. Flint, P. Kellam, D. R. W. Jayne, P. A. Lyons, K. G. C. Smith Analysis of the B cell receptor repertoire in six immune-mediated diseases published pages: 122-126, ISSN: 0028-0836, DOI: 10.1038/s41586-019-1595-3	Nature 574/7776	2020-04-08
2019	Alyce C. Russell, Agnieszka Kepka, Irena TrbojeviÄ‡-AkmaÄiÄ‡, Ivo Ugrina, Manshu Song, Jennie Hui, Michael Hunter, Simon M. Laws, Gordan Lauc, Wei Wang Increased central adiposity is associated with pro-inflammatory immunoglobulin G N-glycans published pages: 110-115, ISSN: 0171-2985, DOI: 10.1016/j.imbio.2018.10.002	Immunobiology 224/1	2020-04-08
2019	Sander Tuit, Camilla Salvagno, Theodore S. Kapellos, Cheei-Sing Hau, Lea Seep, Marie Oestreich, Kathrin Klee, Karin E. de Visser, Thomas Ulas, Joachim L. Schultze Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients published pages: 1221-1235.e5, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2019.09.067	Cell Reports 29/5	2020-04-08
2020	Stefanie Warnat-Herresthal, Konstantinos Perrakis, Bernd Taschler, Matthias Becker, Kevin BaÃŸler, Marc Beyer, Patrick GÃ¼nther, Jonas Schulte-Schrepping, Lea Seep, Kathrin Klee, Thomas Ulas, Torsten Haferlach, Sach Mukherjee, Joachim L. Schultze Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics published pages: 100780, ISSN: 2589-0042, DOI: 10.1016/j.isci.2019.100780	iScience 23/1	2020-04-08
2018	Yukihide Momozawa, Julia Dmitrieva, Emilie ThÃ©Ã¢tre, ValÃ©rie Deffontaine, Souad Rahmouni, BenoÃ®t Charloteaux, FranÃ§ois Crins, Elisa Docampo, Mahmoud Elansary, Ann-Stephan Gori, Christelle Lecut, Rob Mariman, Myriam Mni, CÃ©cile Oury, Ilya Altukhov, Dmitry Alexeev, Yuri Aulchenko, Leila Amininejad, Gerd Bouma, Frank Hoentjen, Mark LÃ¶wenberg, Bas Oldenburg, Marieke J. Pierik, Andrea E. vander Meulen-de Jong, C. Janneke van der Woude, Marijn C. Visschedijk, Mark Lathrop, Jean-Pierre Hugot, Rinse K. Weersma, Martine De Vos, Denis Franchimont, Severine Vermeire, Michiaki Kubo, Edouard Louis, Michel Georges IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-04365-8	Nature Communications 9/1	2020-04-08
2018	Christensen, Robin; Heitmann, Berit L; Andersen, Karina Winther; Nielsen, Ole Haagen; SÃ¸rensen, Signe Bek; Jawhara, Mohamad; Bygum, Anette; Hvid, Lone; Grauslund, Jakob; Wied, Jimmi; Glerup, Henning; Fredberg, Ulrich; Villadsen, Jan Alexander; KjÃ¦r, SÃ¸ren Geill; Fallingborg, Jan; Moghadd, Seyed A G R; Knudsen, Torben; Brodersen, Jacob; FrÃ¸jk, Jesper; Dahlerup, Jens Frederik; Bojesen, Anders Bo; Sorensen, Grith Lykke; Thiel, Steffen; FÃ¦rgeman, Nils J; Brandslund, Ivan; Bennike, Tue Bjerg; Stensballe, Allan; Schmidt, Erik Berg; Franke, Andre; Ellinghaus, David; Rosenstiel, Philip; Raes, Jeroen; Boye, Mette; Werner, Lars; Nielsen, Charlotte Lindgaard; Munk, Heidi Lausten; NexÃ¸e, Anders Bathum; Ellingsen, Torkell; Holmskov, Uffe; Kjeldsen, Jens; Andersen, Vibeke Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases:protocol for a prospective cohort study of prognostic factors and personalised medicine published pages: , ISSN: 2044-6055, DOI: 10.1136/bmjopen-2017-018166	BMJ Open 1	2020-04-08
2018	Sebastian Zeissig, Elisa Rosati, C Marie Dowds, Konrad Aden, Johannes Bethge, Berenice Schulte, Wei Hung Pan, Neha Mishra, Maaz Zuhayra, Marlies Marx, Maren Paulsen, Anne Strigli, Claudio Conrad, DÃ¶rthe Schuldt, Anupam Sinha, Henriette Ebsen, Sabin-Christin Kornell, Susanna Nikolaus, Alexander Arlt, Dieter Kabelitz, Mark Ellrichmann, Ulf LÃ¼tzen, Philip C Rosenstiel, Andre Franke, Stefan Schreiber Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease published pages: , ISSN: 0017-5749, DOI: 10.1136/gutjnl-2018-316023	Gut	2020-04-08
2018	Morgane Sonia Thion, Donovan Low, Aymeric Silvin, Jinmiao Chen, Pauline Grisel, Jonas Schulte-Schrepping, Ronnie Blecher, Thomas Ulas, Paola Squarzoni, Guillaume Hoeffel, Fanny Coulpier, Eleni Siopi, Friederike Sophie David, Claus Scholz, Foo Shihui, Josephine Lum, Arlaine Anne Amoyo, Anis Larbi, Michael Poidinger, Anne Buttgereit, Pierre-Marie Lledo, Melanie Greter, Jerry Kok Yen Chan, Ido Amit, Marc Beyer, Joachim Ludwig Schultze, Andreas Schlitzer, Sven Pettersson, Florent Ginhoux, Sonia Garel Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner published pages: 500-516.e16, ISSN: 0092-8674, DOI: 10.1016/j.cell.2017.11.042	Cell 172/3	2020-04-08
2018	Shaza B Zaghlool, Dennis O Mook-Kanamori, Sara Kader, Nisha Stephan, Anna Halama, Rudolf Engelke, Hina Sarwath, Eman K Al-Dous, Yasmin A Mohamoud, Werner Roemisch-Margl, Jerzy Adamski, Gabi KastenmÃ¼ller, Nele Friedrich, Alessia Visconti, Pei-Chien Tsai, Tim Spector, Jordana T Bell, Mario Falchi, Annika Wahl, Melanie Waldenberger, Annette Peters, Christian Gieger, Marija Pezer, Gordan Lauc, Johannes Graumann, Joel A Malek, Karsten Suhre Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation published pages: 1106-1121, ISSN: 0964-6906, DOI: 10.1093/hmg/ddy006	Human Molecular Genetics 27/6	2020-04-08
2018	Susanna Nikolaus, Georg H. Waetzig, Sven Butzin, Monika Ziolkiewicz, Natalie Al-Massad, Florian Thieme, Ulf LÃ¶vgren, Birgitte B. Rasmussen, Torsten M. Reinheimer, Dirk Seegert, Philip Rosenstiel, Silke Szymczak, Stefan Schreiber Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases published pages: 927-936, ISSN: 0179-1958, DOI: 10.1007/s00384-018-3069-8	International Journal of Colorectal Disease 33/7	2020-04-08
2018	JN Liu, M Dolikun, J Å tambuk, I TrbojeviÄ‡-AkmaÄiÄ‡, J Zhang, H Wang, DQ Zheng, XY Zhang, HL Peng, ZY Zhao, D Liu, Y Sun, Q Sun, QH Li, JX Zhang, M Sun, WJ Cao, A MomÄiloviÄ‡, G. Razdorov, LJ Wu, A Russell, YX Wang, MS Song, G Lauc, W Wang The association between subclass-specific IgG Fc N-glycosylation profiles and hypertension in the Uygur, Kazak, Kirgiz, and Tajik populations published pages: , ISSN: 0950-9240, DOI: 10.1038/s41371-018-0071-0	Journal of Human Hypertension	2020-04-08
2018	Ivan Gudelj, Perttu P. Salo, Irena TrbojeviÄ‡-AkmaÄiÄ‡, Malena Albers, Dragan Primorac, Markus Perola, Gordan Lauc Low galactosylation of IgG associates with higher risk for future diagnosis of rheumatoid arthritis during 10â€¯years of follow-up published pages: 2034-2039, ISSN: 0925-4439, DOI: 10.1016/j.bbadis.2018.03.018	Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1864/6	2020-04-08
2018	Kate Joanne Howell, Judith Kraiczy, Komal M. Nayak, Marco Gasparetto, Alexander Ross, Claire Lee, Tim N. Mak, Bon-Kyoung Koo, Nitin Kumar, Trevor Lawley, Anupam Sinha, Philip Rosenstiel, Robert Heuschkel, Oliver Stegle, Matthias Zilbauer DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory BowelÂ Diseases Differentiate Disease Subtypes and Associate With Outcome published pages: 585-598, ISSN: 0016-5085, DOI: 10.1053/j.gastro.2017.10.007	Gastroenterology 154/3	2020-04-08
2018	Jasminka KriÅ¡tiÄ‡, Olga O. Zaytseva, Ramesh Ram, Quang Nguyen, Mislav Novokmet, Frano VuÄkoviÄ‡, Marija Vilaj, Irena TrbojeviÄ‡-AkmaÄiÄ‡, Marija Pezer, Kathleen M. Davern, Grant Morahan, Gordan Lauc Profiling and genetic control of the murine immunoglobulin G glycome published pages: 516-524, ISSN: 1552-4450, DOI: 10.1038/s41589-018-0034-3	Nature Chemical Biology 14/5	2020-04-08
2017	Elisa Rosati, C Marie Dowds, Evaggelia Liaskou, Eva Kristine Klemsdal Henriksen, Tom H Karlsen, Andre Franke Overview of methodologies for T-cell receptor repertoire analysis published pages: , ISSN: 1472-6750, DOI: 10.1186/s12896-017-0379-9	BMC Biotechnology 17/1	2020-04-08
2017	Doris Vandeputte, Gunter Kathagen, Kevin Dâ€™hoe, Sara Vieira-Silva, Mireia Valles-Colomer, JoÃ£o Sabino, Jun Wang, Raul Y. Tito, Lindsey De Commer, Youssef Darzi, SÃ©verine Vermeire, Gwen Falony, Jeroen Raes Quantitative microbiome profiling links gut community variation to microbial load published pages: 507-511, ISSN: 0028-0836, DOI: 10.1038/nature24460	Nature 551	2020-04-08
2018	Marko Kosicek, Ivan Gudelj, Anita Horvatic, Tanja Jovic, Frano Vuckovic, Gordan Lauc, Silva Hecimovic N-glycome of the Lysosomal Glycocalyx is Altered in Niemann-Pick Type C Disease (NPC) Model Cells published pages: 631-642, ISSN: 1535-9476, DOI: 10.1074/mcp.RA117.000129	Molecular & Cellular Proteomics 17/4	2020-04-08
2018	Mirna Å imurina, Noortje de Haan, Frano VuÄkoviÄ‡, Nicholas A. Kennedy, Jerko Å tambuk, David Falck, Irena TrbojeviÄ‡-AkmaÄiÄ‡, Florent Clerc, Genadij Razdorov, Anna Khon, Anna Latiano, Renata D\'IncÃ , Silvio Danese, Stephan Targan, Carol Landers, Marla Dubinsky, Dermot P.B. McGovern, Vito Annese, Manfred Wuhrer, Gordan Lauc, Harry Campbell, Vlatka ZoldoÅ¡, Iain K. Permberton, Daniel Kolarich, Daryl L. Fernandes, Evropi Theorodorou, Victoria Merrick, Daniel I. Spencer, Richard A. Gardner, Ray Doran, Archana Shubhakar, Ray Boyapati, Igor Rudan, Paolo Lionetti, Jasminka KriÅ¡tiÄ‡, Mislav Novokmet, Maja PuÄiÄ‡-BakoviÄ‡, Olga Gornik, Angelo Andriulli, Laura Cantoro, Giancarlo Sturniolo, Gionata Fiorino, Natalia Manetti, Ian D. Arnott, Colin L. Noble, Charlie W. Lees, Alan G. Shand, Gwo-Tzer Ho, Malcolm G. Dunlop, Lee Murphy, Jude Gibson, Louise Evenden, Nicola Wrobel, Tamara Gilchrist, Angie Fawkes, Guinevere S.M. Kammeijer, Aleksandar Vojta, Ivana SamarÅ¾ija, Dora Markulin, Marija KlasiÄ‡, Paula DobriniÄ‡, Yurii Aulchenko, Tim van den Heuve, Daisy Jonkers, Marieke Pierik Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases published pages: 1320-1333.e10, ISSN: 0016-5085, DOI: 10.1053/j.gastro.2018.01.002	Gastroenterology 154/5	2020-04-08
2018	Joachim L. Schultze, Philip Rosenstiel Systems Medicine in Chronic Inflammatory Diseases published pages: 608-613, ISSN: 1074-7613, DOI: 10.1016/j.immuni.2018.03.022	Immunity 48/4	2020-04-08
2017	Felix Sommer, Jacqueline Moltzau Anderson, Richa Bharti, Jeroen Raes, Philip Rosenstiel The resilience of the intestinal microbiota influences health and disease published pages: 630-638, ISSN: 1740-1526, DOI: 10.1038/nrmicro.2017.58	Nature Reviews Microbiology 15/10	2020-04-08
2017	Xia Shen, Lucija KlariÄ‡, Sodbo Sharapov, Massimo Mangino, Zheng Ning, Di Wu, Irena TrbojeviÄ‡-AkmaÄiÄ‡, Maja PuÄiÄ‡-BakoviÄ‡, Igor Rudan, Ozren PolaÅ¡ek, Caroline Hayward, Timothy D. Spector, James F. Wilson, Gordan Lauc, Yurii S. Aulchenko Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-017-00453-3	Nature Communications 8/1	2020-04-08
2017	Susanna Nikolaus, Berenice Schulte, Natalie Al-Massad, Florian Thieme, Dominik M. Schulte, Johannes Bethge, Ateequr Rehman, Florian Tran, Konrad Aden, Robert HÃ¤sler, Natalie Moll, Gregor SchÃ¼tze, Markus J. Schwarz, Georg H. Waetzig, Philip Rosenstiel, Michael Krawczak, Silke Szymczak, Stefan Schreiber Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases published pages: 1504-1516.e2, ISSN: 0016-5085, DOI: 10.1053/j.gastro.2017.08.028	Gastroenterology 153/6	2020-04-08
2017	Vibeke Andersen, Uffe Holmskov, Signe SÃ¸rensen, Mohamad Jawhara, Karina Andersen, Anette Bygum, Lone Hvid, Jakob Grauslund, Jimmi Wied, Henning Glerup, Ulrich Fredberg, Jan Villadsen, SÃ¸ren KjÃ¦r, Jan Fallingborg, Seyed Moghadd, Torben Knudsen, Jacob Brodersen, Jesper FrÃ¸jk, Jens Dahlerup, Ole Nielsen, Robin Christensen, Anders Bojesen, Grith Sorensen, Steffen Thiel, Nils FÃ¦rgeman, Ivan Brandslund, Allan Stensballe, Erik Schmidt, Andre Franke, David Ellinghaus, Philip Rosenstiel, Jeroen Raes, Berit Heitmann, Mette Boye, Charlotte Nielsen, Lars Werner, Jens Kjeldsen, Torkell Ellingsen A Proposal for a Study on Treatment Selection and Lifestyle Recommendations in Chronic Inflammatory Diseases: A Danish Multidisciplinary Collaboration on Prognostic Factors and Personalised Medicine published pages: 499, ISSN: 2072-6643, DOI: 10.3390/nu9050499	Nutrients 9/5	2020-04-08

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