The page lists 203 projects related to the topic "alterations".
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1 | MODELAGE | Is your heart aging well? A systems biology approach to characterize cardiac aging from the cell to the body surface | 2015 |
2 | EPICUP | Development of a ncRNA DNA Methylation Kit for the Diagnosis of Cancer of Unknown Primary | 2015 |
3 | VEGFDANI | Novel enhancers of functional recovery after stroke | 2015 |
4 | RetinArt | Clinical biomarker for arterial hypertension based on micro-vascular retinal imaging | 2014 |
5 | Cancer-Drug-Screen | High-throughput drug screening for identifying personalized cancer treatments tailored to the particular mutations of the patient’s tumor | 2015 |
6 | CircaDopamine | The Role of Dopamine in the Regulation of Sleep and Circadian Rhythms | 2015 |
7 | ReprObesity | Overweight-induced Hypogonadism as major factor for the generation and/or perpetuation of Metabolic Co-morbidities of Obesity: Contribution of Epigenetic Regulatory Mechanisms | 2016 |
8 | 7DUP | Characterization of 7q11.23 reciprocal aneusomy syndromes: from patients to functional pathways (and back) | 2016 |
9 | GOMB-TBI | Causes and consequences of alterations in cerebral glucose metabolism in Traumatic Brain Injury | 2015 |
10 | River-HMV | River hydraulics, morphology, and vegetation: A case for improved knowledge and numerical model capabilities | 2015 |
11 | QuantMR7 | Quantitative MRI of the brain using magnetic resonance fingerprinting | 2016 |
12 | TARGEPILIVER | Characterization of Key Epigenetic Targets in Hepatic Fibrosis and Hepatocellular Carcinoma Development. Generation of New Antifibrotic and Antitumoral Drugs. | 2015 |
13 | TEMPI | The Time of Early Metalwork in Prehistoric Italy | 2015 |
14 | PERMTHAW | Permafrost thaw – decadal responses to climate change | 2016 |
15 | ISSVS | Immune system involvement in sex-specific vulnerability to prenatal stress | 2015 |
16 | GCP-GEOTARCTIC | Geochemical-physical coupled study of the modern Arctic Ocean: GEOTRACES-ARCTIC | 2015 |
17 | MYO-DESMOPLASIA | Modulating the behaviour of cancer myofibroblasts to control tumour desmoplasia | 2015 |
18 | MUSIC | How the brain creates Mutual Understanding during Social InteraCtion | 2016 |
19 | NEURINFDNA | Neuronal DNA double strand breaks as novel epigenetic actors: roles in cognition, health and neuro-inflammatory diseases | 2016 |
20 | smSTRUCT | Fuse smFRET and modeling to a new structural biology method and solve the functional ESCRT assembly structure | 2016 |
21 | FiBRO | Fibroblasts in the Biology of Rectal Cancer Progression | 2016 |
22 | BRIDGES | Bioinformatic approaches to identify and detect both disease- and drug-related genomic alterations in breast cancer patients | 2015 |
23 | depreg | Antidepressants during pregnancy: underlying mechanisms associated with neurodevelopmental outcome | 2015 |
24 | ACM | Cholesterol metabolism as a driver of prostate cancer aggressiveness | 2015 |
25 | S-OS | Exosomes as microenvironmental cue for engaging mesenchymal stem cells in osteosarcoma progression | 2016 |
26 | VMHCIRCUITS | Deciphering central role of VMH circuits in regulating energy balance | 2015 |
27 | PICSIMA | Next generation 3D print technology (PICSIMA), which for the first time enables the direct full colour printing of silicone to make soft tissue prostheses, orthoses and removable partial dentures. | 2015 |
28 | Inflammostrome | Stromal cells as primary drivers of immunopathology: towards targeted disease modification in spondyloarthritis | 2015 |
29 | SPICE | Synthetic Lethal Phenotype Identification through Cancer Evolution Analysis | 2015 |
30 | IMMUNOBIOME | Identifying microbiotal triggers of inflammatory bowel disease through the lens of the immune system | 2016 |
31 | COMAL | COMAL:COhesin Mutations in Acute Leukemia: from modeling and mechanisms to novel therapeutics | 2015 |
32 | Phd | Deciphering PI3K biology in health and disease | 2015 |
33 | BtRAIN | Brain barriers training | 2015 |
34 | MuG | Multi-Scale Complex Genomics | 2015 |
35 | NutrientSensingVivo | The Physiology of Nutrient Sensing by mTOR | 2016 |
36 | SEGWAY | Study on Environmental and GenomeWide predictors of early structural brain Alterations in Young students | 2015 |
37 | RNAEDIT | RNA EDITING IN HEALTH AND DISEASE | 2016 |
38 | BioBarPro | A Hot-Spot Bio-Barcode Strategy for Prognostic Biomarkers In Colorectal Cancer | 2015 |
39 | COSYN | Comorbidity and Synapse Biology in Clinically Overlapping Psychiatric Disorders | 2016 |
40 | CFS modelling | Chromosomal Common Fragile Sites: Unravelling their biological functions and the basis of their instability | 2016 |
41 | PrECISE | PERSONALIZED ENGINE FOR CANCER INTEGRATIVE STUDY AND EVALUATION | 2016 |
42 | Crossover control | New insights into wheat meiosis: Crossover resolution in the absence of the Ph1 locus | 2016 |
43 | CMIL | Crosstalk of Metabolism and Inflammation | 2016 |
44 | NEUROGOAL | Neuronal Coding of Choice and Action-Selection during Decision-Making in Behaving Mice | 2016 |
45 | PolyDomFormFuncReg | Discovering how polycomb domains form and function in gene regulation | 2016 |
46 | DynamAtt | Dynamics of Attentional Networks in the Human Brain in Health and Disease: Evidence from Intracerebral and MEG Recordings | 2017 |
47 | PDA_TGFb | TGF-beta mediated crosstalk between cancer (stem) cells and tumor microenvironment in pancreatic cancer metastasis | 2017 |
48 | NeuroASPECT | Neuronal Alternative Splicing and RNA-Editing Crosstalk | 2017 |
49 | SYNVIA | Synthetic viability of homologous recombination-deficient cancers | 2016 |
50 | TSGPs-of-CFSs | Role of Tumour Suppressor Gene Products of Common Fragile Sites in Human Diseases | 2016 |
51 | ONCOINTRABODY | Targeting common oncogenes with intracellular monobodies | 2016 |
52 | MEMORAGE | Attention and memory components in every-day cognitive problems in aging | 2017 |
53 | DECODE | Allele-specific Deconvolution of Tumour DNA Methylation and Expression Data toReveal Underlying Cell Populations | 2016 |
54 | Wnt and CRC | Therapeutic inhibition of the oncogenic Wnt/beta-catenin pathway in mismatch repair deficient hypermutant tumors | 2017 |
55 | WntELECT | Wnt Enhancer LandscapE CharacTerization | 2016 |
56 | NPAD | Multiregional rtfMRI Neurofeedback for the Prevention of Alzheimer's Disease | 2016 |
57 | AGORAs | AGeing effects on human aORta: from shApe to flowS | 2016 |
58 | EpigenomeProgramming | An experimental and bioinformatic toolbox for functional epigenomics and its application to epigenetically making and breaking a cancer cell | 2016 |
59 | MIDOC | Multimodal Imaging of Disorders of Consciousness | 2016 |
60 | neuroXscales | Microtechnology and integrated microsystems to investigate neuronal networks across scales | 2016 |
61 | DMD2CURE | Correction of duplications in the DMD gene by a CRISPR/Cas9 approach | 2017 |
62 | DEMETINL | Decisions in metabolic inflammation of the liver: Adhesive interactions involved in leukocyte retention and resolution of inflammation in metabolic-inflammatory liver disease | 2017 |
63 | STEM-BCPC | Signal Transduction and Epigenetic Mechanisms of Breast Cell Plasticity and Cancer | 2016 |
64 | ImmunoBile | Bile acid, immune-metabolism, lipid and glucose homeostasis | 2016 |
65 | LEASP | Learning spatiotemporal patterns in longitudinal image data sets of the aging brain | 2016 |
66 | INTEGRAL | Signal Integration by Gene Regulatory Landscapes | 2016 |
67 | LYSOTRACK | Defining the role of lysosomal trafficking in age-associated anabolic resistance in human skeletal muscle | 2016 |
68 | LSDiASD | Leveraging Small Demethylase inhibitors for Autism Spectrum Disorder | 2016 |
69 | STRESNET | Stress Resilience and Network-Feedback Training | 2016 |
70 | MATRICAN | Matrix during cancer progression | 2016 |
71 | TransSplicHD | Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington’s Disease. | 2016 |
72 | AstroWireSyn | Wiring synaptic circuits with astroglial connexins: mechanisms, dynamics and impact for critical period plasticity | 2016 |
73 | RACE | Rate of Adaptation in a Changing Environment | 2017 |
74 | ALZSYN | Imaging synaptic contributors to dementia | 2016 |
75 | Neuroheart | Cardiovascular Molecular Imaging for Personalized Tailored Treatment | 2017 |
76 | LIFE synapses | Long-term Investigation of Functional Excitatory Synapses: Linking Plasticity, Network Wiring andMemory Storage | 2017 |
77 | SYSCID | A Systems medicine approach to chronic inflammatory disease | 2017 |
78 | VISORSURF | VisorSurf - A Hardware Platform for Software-driven Functional Metasurfaces | 2017 |
79 | BETA-BACT | Beta-cell inflammation and dysfunction induced by bacterial translocation | 2016 |
80 | Circdyn | Optical Interrogation of Hippocampal Dentate Granule Circuit Dynamics in Health and Disease | 2017 |
81 | SCUBA CANCERS | Finding the genetic causes of contagious metastases under the sea | 2017 |
82 | CancerFluxome | Cancer Cellular Metabolism across Space and Time | 2017 |
83 | COLGENES | Defining novel mechanisms critical for colorectal tumourigenesis | 2017 |
84 | GlycoModels | 3D glyco-engineered models to address the role of glycosylation in gastric cancer clinical management | 2017 |
85 | Cetacean Inner Ear | Cetacean Inner Ear | 2017 |
86 | MITOSENSING | Decoding mitochondrial nutrient-sensing programs in POMC neurons as key determinants of metabolic health | 2017 |
87 | ConCorND | Connectivity Correlate of Molecular Pathology in Neurodegeneration | 2017 |
88 | Schizo-EPICOG | Inflammatory processes underlying cognitive deficits in schizophrenia: epigenetic mechanisms and pharmacological regulation | 2018 |
89 | SHYDRO-ALP | Quantifying ecological effects of small hydropower in Alpine stream ecosystems | 2017 |
90 | NETBIO-GE | Quantitative brain network biomarkers for patient-specific diagnostics in idiopathic generalized epilepsy | 2017 |
91 | FABCARB | Fermentation And behaviour of carbohydrates in the colon | 2017 |
92 | DNAmethAML | Investigation of aberrant DNA methylation in malignant haematopoiesis | 2018 |
93 | DNCSS | Decoding neural circuits controlling sleep drive and sedation | 2018 |
94 | TeloChromatin | Dissecting the chromatin dynamics at telomeres during mouse pre-implantation development. | 2017 |
95 | IAPEMIDE | Impact of Intrapartum Antimicrobial Prophylaxis as an early determinant in Microbiome Development | 2017 |
96 | YEFF | Comprehensive analysis of yeast expression-fitness functions (EFFs) | 2018 |
97 | PI3K-VAs | Activation of PI3K signalling in the pathogenesis of Vascular Anomalies | 2018 |
98 | METCLL | Discovery and validation of ‘epidrivers’ of cancer evolution and resistance to therapy | 2018 |
99 | funcSOFI-PD | Quantitative super-resolution optical fluctuation and phase microscopy for structural and functional imaging of Parkinson's disease | 2017 |
100 | RoNDBioCan | NLRP3 in cancer: Deciphering the role of NLRP3 in the DNA Damage response pathway | 2018 |
101 | HERPES | Herpesvirus Effectors of RNA synthesis, Processing, Export and Stability | 2017 |
102 | BEAT | The functional interaction of EGFR and beta-catenin signalling in colorectal cancer: Genetics, mechanisms, and therapeutic potential. | 2017 |
103 | CFZEBRA | Balancing the immune response in cystic fibrosis: using zebrafish models of infection and inflammation to uncover new therapeutic approaches | 2017 |
104 | REPRODAMH | Extra-gonadal roles of Anti-Müllerian Hormone in the aetiology of polycystic ovary syndrome: the domino effect to reproductive neuroendocrine dysfunctions | 2017 |
105 | MECSPEC | Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation | 2017 |
106 | DynaCOMP | Assessing compounds targeting DNA replication licensing complexes as anti-tumor agents | 2017 |
107 | SYNEME | Systems Neuroscience of Metabolism | 2017 |
108 | DeAge | Deconstructing Ageing: from molecular mechanisms to intervention strategies | 2017 |
109 | IMBIBE | Innovative technology solutions to explore effects of the microbiome on intestine and brain pathophysiology | 2017 |
110 | ORGANOMICS | Reconstructing human cortex development and malformation with single-cell transcriptomics | 2018 |
111 | TissueLymphoContexts | Tissue-resident Lymphocytes: Development and Function in “real-life” Contexts | 2018 |
112 | GRIMASSE | General aviation Rescue capacity IMprovement for the worldwide Adoption of a Safe Solution based on European GNSS | 2017 |
113 | MERLIN | Multi-modal, multi-scale retinal imaging | 2017 |
114 | MEL-Interactions | An integrative approach for the exploration of melanoma genetic and immunological interactions | 2018 |
115 | COMPLEX-FISH | Complex eco-evolutionary dynamics of aquatic ecosystems faced with human-induced and environmental stress | 2018 |
116 | BirNonArchGeom | Birational and non-archimedean geometries | 2018 |
117 | NonChroRep | Investigating the role of the long noncoding transcriptome in chromatin replication | 2018 |
118 | EMERGE | Epigenetic and metabolic regulation of endothelial heterogeneity | 2018 |
119 | UTERUS | Unravelling gamma delta T cell emergence and responses in the uterus | 2018 |
120 | PfPHIST | Characterisation of the Plasmodium PHIST protein family | 2018 |
121 | ConnectExAct-Age | Brain Connectivity for Executive Control over Action in Ageing | 2018 |
122 | MaGMa | Applying Metabolomics to Unveil follow-up treatment biomarkers and Identify Novel TherapeuticTargets in Glioblastoma | 2018 |
123 | CIOP | Centrifugal Instability in the Orkney Passage | 2018 |
124 | DYNAMET | Interplay of plant one-carbon metabolism and redox homeostasis in the context of dynamic DNA methylation (DYNAMET) | 2018 |
125 | EnCAge | Progeria models to study endothelial cell ageing: implications for organ regeneration and fibrosis | 2020 |
126 | MyelinPlasticity | Neuronal regulation of CNS myelin plasticity | 2018 |
127 | UB-RASDisease | The ubiquitin system in RAS-driven disease | 2018 |
128 | VALSL | Valorisation of splice-switching oligonucleotides for lung cancer therapy | 2018 |
129 | MultiSpecAMYLOID | A MULTI-SPECTROSCOPIC APPROACH TO PROBE AMYLOID AGGREGATION AT BIOLOGICAL SURFACES | 2018 |
130 | NOISE | NOise Impacts of whale-watching boatS on cEtaceans | 2018 |
131 | HifLICs | Acute Myeloid Leukemia Leukemic Initiating Cells: Contribution of hypoxia/HIF pathway to chemoresistance and relapse | 2019 |
132 | ASTRO_ECM | Deciphering the role of astrocytes in chronic depression. | 2018 |
133 | REPTOL | Pre-leukemic B cell repertoire alterations in patients with familial chronic lymphocytic leukemia: looking for evidence of a genetically-inherited defect in tolerance induction | 2019 |
134 | PFC-AMY | Functional networks underlying emotion processing | 2018 |
135 | SOCIALBRAINCIRCUITS | Neuroanatomical substrates of social deficit in a mouse model of 22q11 deletion syndrome | 2018 |
136 | GLIAMAC | Uncovering Enteric GLIA-MACrophage communication in the intestinal homeostasis and inflammation | 2018 |
137 | M-Lysosomes | Identification of a novel function of lysosomes in mitosis for cancer therapy | 2019 |
138 | Newron-TBI | Neurogenesis-related changes in hippocampal new neurons and circuits after traumatic brain injury | 2018 |
139 | PhaseControl | How cellular suicide programmes control phase transitions in fatty liver disease and liver cancer | 2018 |
140 | DARE2APPROACH | Dare to Approach: A Neurocognitive Approach to Alleviating Persistent Avoidance in Anxiety Disorders | 2019 |
141 | MECHEMGUI | The integration of mechanical and chemical signals in neuronal guidance | 2018 |
142 | eCAPE | New energy Consumer roles and smart technologies – Actors, Practices and Equality | 2018 |
143 | SENSITIVE | Early Detection of cancer onset based on sensing field cancerization at the organ level | 2018 |
144 | Gut_Fights_PD | Investigating protective mechanisms of gut bacteria in C. elegans models of Parkinson’s disease | 2019 |
145 | Primavera | Primavera: immunobiotics for treating early stage Age-related Macular Degeneration (AMD) | 2018 |
146 | ChromDesign | Chromatin architecture and Design | 2018 |
147 | PATER | Paternal Epigenetic Inheritance: A man’s life experiences may impact health of his unborn children and grandchildren | 2019 |
148 | METANICHE | Regulation of bone metastases by age-associated angiocrine signals | 2019 |
149 | EPIORGABOLISM | Diabetic nephropathy modelling in hESC-derived 3D kidney organoids | 2019 |
150 | bECOMiNG | spontaneous Evolution and Clonal heterOgeneity in MoNoclonal Gammopathies: from mechanisms of progression to clinical management | 2019 |
151 | REMIND | Epigenome maintenance in response to DNA damage | 2019 |
152 | iHEAR | Gene therapy of inherited and acquired hearing loss | 2019 |
153 | SCHIZTYPE | Brain cell type-specific interactions and schizophrenia | 2019 |
154 | CRC-MTOs | Colorectal Cancer Mouse Tumor Organoids as Pre-clinical Models for Therapeutical Testing | 2018 |
155 | skILL | Intracellular signalling by modified lipopolysaccharide | 2019 |
156 | PATRES-MDS | Pathogenesis and treatment of splicing factor mutant myelodysplastic syndromes | 2019 |
157 | Kinaddict | Vulnerability of esophageal cancer to their addiction to kinase activities: evaluation and prediction of eSCC tumors responsiveness to kinase inhibitors. | 2019 |
158 | TaPPiNG-EPI | Targeting Purinergic Pathway in drug-resistant epilepsy using human Neurons and Glia. | 2019 |
159 | AmygdalaNeuroMod | Unraveling the combinatorial logic of amygdala neuromodulation in decision-making and learning. | 2020 |
160 | Degradation_ID | The role of protein degradation in FBXO11-related intellectual disability | 2019 |
161 | PredAlgoBC | Machine learning prediction for breast cancer therapy | 2019 |
162 | CRISPR-KissCas9 | Challenging the KNDy Hypothesis Using CRISPR-Cas9 Genome Editing: Evaluation of the Role of Neurokinin B and Dynorphin in Kiss1 neurons in the Control of Fertility | 2020 |
163 | NeuroSens | Neuromodulation of Sensory Processing | 2019 |
164 | CancerADAPT | Targeting the adaptive capacity of prostate cancer through the manipulation of transcriptional and metabolic traits | 2019 |
165 | WoMent | 'Mad for Him'. Women, Religion and Mental Illness in the Late Middle Ages and in the Early Modern Age | 2019 |
166 | CaRe-Space | Cajal-Retzius cells role in the development of the spatial navigation system | 2020 |
167 | RTTOPHAGY | """Investigating autophagy enhancement as a therapeutic approach for the treatment of Rett syndrome.""" | 2019 |
168 | CausalBrain | Dynamic directed functional connectivity of causal learning | 2019 |
169 | EPICAN | Inhibiting tumor cell plasticity by targeting the epigenome in breast cancer | 2020 |
170 | CANSAS | Clustering functional connectivity alterations in Autism Spectrum Disorders | 2020 |
171 | FACETS | Face Aesthetics in Contemporary E-Technological Societies | 2019 |
172 | ALCO-ADO | Unveiling the alcohol-dependent alterations in local dendritic translation of mRNAs in the prefrontal cortex during adolescence | 2019 |
173 | DEEPDREAM | A Data-drivEn computational mEthod for PersonalizeD healthcare in chronic REspiratory diseases through big-dAta analytics and dynamical Modelling. | 2020 |
174 | FunStructure | Interdependence of functional and structural plasticity in cerebellar climbing fibers in health and disease | 2019 |
175 | INVADERS | Mucus-Penetrating Microbiota: Characterization, Mechanism and Therapeutic in Metabolic Disease | 2019 |
176 | PALADYN | New geochemical approach to reconstruct tropical palaeo-atmospheric dynamics | 2019 |
177 | EULAT Eradicate GBC | Establishment and Exploitation of a European-Latin American Research Consortium towards Eradication of Preventable Gallbladder Cancer | 2019 |
178 | MetaboSENS | Metabolic integration by nutrient SENSing | 2019 |
179 | MODSTABVAR | Moduli spaces of stable varieties and applications | 2020 |
180 | SAND | Secretion, Autophagy and their role in Neurodegeneration | 2019 |
181 | EARLYDETECT | Development of an accurate, early diagnostic tool for ovarian cancer | 2020 |
182 | XpeFundus | A smart hyperspectral system for early, non-invasive diagnosis of retinal disease | 2020 |
183 | miniNO | Associative mechanisms linking a defective minipuberty to the appearance of mental and nonmental disorders: infantile NO replenishment as a new therapeutic possibility | 2020 |
184 | MAD | Mechanisms of Apomictic Developments | 2020 |
185 | PreSynPlast | Molecular mechanisms of presynaptic plasticity | 2020 |
186 | CTS-TEs-ADprogress | Cell type-specific molecular analysis of epigenetic changes and transposable element derepression in Alzheimer's disease progression | 2020 |
187 | DIFFER | Determinants of genetic diversity: Important Factors For Ecosystem Resilience | 2020 |
188 | SERWOM | Understanding Serotonergic Regulation of Working Memory | 2020 |
189 | C.A.R.E. OA | Cross-linking Adenosine Receptors - Estrogen receptors for OA treatment | 2021 |
190 | ParkIFNAR | Soluble IFNAR2 in Parkinson's disease and its role in the regulation of IFNβ in a neuroinflammatory context. | 2020 |
191 | PTSD Neurofeedback | Regulating Pathological Neural Connectivity in Posttraumatic Stress Disorder | 2020 |
192 | MicroILCs | "MicroILCs: Deciphering how the gut Microbiota influences Innate Lymphoid Cells in obesity""" | 2021 |
193 | ChaConGen | Exploring the role of host-parasite genotypes in the congenital transmission of Chagas disease: an emergent infectious disease in Europe | 2021 |
194 | ChRONAM-H | Chromatin Regulation Of Normal And Malignant Haematopoiesis | 2020 |
195 | PIANISM | Prefrontal Cortex Circuit Dynamics underlying Working Memory and its Serotonin Modulation | 2020 |
196 | RegARcis | Role of the SWI/SNF complex in the Androgen Receptor cistrome regulation | 2020 |
197 | POMOLIM | Polycystic ovarian syndrome: novel molecular characterization and personalized in vitro maturation protocol. | 2020 |
198 | PDASwITch | Super-enhancer modules controlling plasticity and response to therapy in pancreatic cancer | 2020 |
199 | PATHOCODE | Molecular pathology of anti-viral T cell responses in the central nervous system | 2020 |
200 | CAPTUR3D | CAPTURING THE PHYSICS OF LIFE ON 3D-TRAFFICKING SUBCELLULAR NANOSYSTEMS | 2020 |
201 | NEUROPREG | Eating patterns in pregnancy: unraveling the underlying neurocircuits and its deleterious metabolic consequences | 2021 |
202 | EscaPI | Exploring the non-genetic (i.e. ePIgenetic) mechanisms that contribute to therapy Escape in melanoma | 2020 |
203 | NormNets | Normalization of Multimodal Brain Networks for Integral and Predictive Mapping of Neurological Disorders | 2020 |