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M-CUBE SIGNED

MetaMaterials antenna for ultra-high field MRI

Total Cost €

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EC-Contrib. €

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Partnership

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Outcomes and
results

M-CUBE project word cloud

Explore the words cloud of the M-CUBE project. It provides you a very rough idea of what is the project "M-CUBE" about.

materials ultra scientifically consists academic smes volunteers eight resonance radically limited changing structures disruptive breakthrough leaders physicians tackle solutions active designed doctors resolutions metamaterial imaging optical interdisciplinary lack rf detect technological nature index scanners tailor diagnosis context structured guarantee sar multiple physicists accurate centered medical cube passive composite homogeneity relies antenna barriers metamaterials coil tests mri actors frequency electromagnetic rate unavailable earlier closely expectations antennas body m waves negative limits industrial absorption diagnostically validated manmade drastically solution preclinical healthy detection innovative diseases human spatial patient disease personalized universities clinical radio temporal pave idea paradigm magnetic medicine expensive

Project "M-CUBE" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITE D'AIX MARSEILLE Organization address address: Boulevard Charles Livon 58 city: Marseille postcode: 13284 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Project website	http://www.mcube-project.eu/
Total cost	4˙582˙346 €
EC max contribution	3˙945˙346 € (86%)
Programme	1. H2020-EU.1.2.1. (FET Open)
Code Call	H2020-FETOPEN-1-2016-2017
Funding Scheme	RIA
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2020-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITE D'AIX MARSEILLE UNIVERSITE D'AIX MARSEILLE Organization address address: Boulevard Charles Livon 58 city: Marseille postcode: 13284 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (Marseille)	coordinator	1˙230˙023.00
2	COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES Organization address address: RUE LEBLANC 25 city: PARIS 15 postcode: 75015 website: www.cea.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS 15)	participant	705˙256.00
3	UNIVERSITAIR MEDISCH CENTRUM UTRECHT UNIVERSITAIR MEDISCH CENTRUM UTRECHT Organization address address: HEIDELBERGLAAN 100 city: UTRECHT postcode: 3584 CX website: www.umcutrecht.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (UTRECHT)	participant	468˙778.00
4	UNIVERSITE CATHOLIQUE DE LOUVAIN UNIVERSITE CATHOLIQUE DE LOUVAIN Organization address address: PLACE DE L UNIVERSITE 1 city: LOUVAIN LA NEUVE postcode: 1348 website: www.uclouvain.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LOUVAIN LA NEUVE)	participant	318˙941.00
5	AALTO KORKEAKOULUSAATIO SR AALTO KORKEAKOULUSAATIO SR Organization address address: OTAKAARI 1 city: ESPOO postcode: 2150 website: http://www.aalto.fi/en/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (ESPOO)	participant	313˙125.00
6	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS Organization address address: RUE MICHEL ANGE 3 city: PARIS postcode: 75794 website: www.cnrs.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	312˙250.00
7	MULTIWAVE TECHNOLOGIES AG MULTIWAVE TECHNOLOGIES AG Organization address address: 3 CHEMIN DU PRE FLEURI city: GENEVA postcode: 1228 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (GENEVA)	participant	250˙625.00
8	MR COILS BV MR COILS BV Organization address address: SHIMMINCK 18 city: ZALTBOMMEL postcode: 5301 KR website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ZALTBOMMEL)	participant	233˙846.00
9	TESLA DYNAMIC COILS BV TESLA DYNAMIC COILS BV Organization address address: SCHIMMINCK 12 city: ZALTBOMMEL postcode: 5301KR website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ZALTBOMMEL)	participant	112˙500.00
10	ITMO UNIVERSITY ITMO UNIVERSITY Organization address address: KRONWERKSKIY PROSP 49 city: ST PETERSBURG postcode: 197101 website: http://en.ifmo.ru/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	RU (ST PETERSBURG)	participant	0.00
11	THE AUSTRALIAN NATIONAL UNIVERSITY THE AUSTRALIAN NATIONAL UNIVERSITY Organization address address: LIVERSIDGE STREET 1 BUILDING 67C city: CANBERRA postcode: 200 website: http://researchservices.anu.edu.au/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AU (CANBERRA)	participant	0.00

Map

Project objective

M-Cube aims at changing the paradigm of High-Field MRI and Ultra High-Field antennas to offer a much better insight on the human body and enable earlier detection of diseases. Our main objective is to go beyond the limits of MRI clinical imaging and radically improve spatial and temporal resolutions. The clinical use of High-field MRI scanners is drastically limited due to the lack of homogeneity and to the Specific Absorption Rate (SAR) of the Radio Frequency (RF) fields associated with the magnetic resonance. The major way to tackle and solve these problems consists in increasing the number of active RF antennas, leading to complex and expensive solutions. M-Cube solution relies on innovative systems based upon passive metamaterial structures to avoid multiple active elements. These systems are expected to make High-Field MRI fully diagnostically relevant for physicians. To achieve these expectations, M-Cube consortium will develop a disruptive metamaterial antenna technology. This we will able us to tackle both the lack of homogeneity and SAR barriers. Metamaterials are composite structured manmade materials designed to produce effective properties unavailable in nature (e.g. negative optical index). They allow us to tailor electromagnetic waves at will. Thus, the scientifically ambitious idea is to develop antennas based on this unique ability for whole body coil. This technological breakthrough will be validated by preclinical and clinical tests with healthy volunteers. M-Cube gathers an interdisciplinary consortium composed of academic leaders in the field, eight universities, and two promising SMEs. Physicists, medical doctors and industrial actors will work closely all along the implementation of the project to guarantee the success this novel approach, a “patient-centered” solution which will pave the way for a more accurate diagnosis in the context of personalized medicine and will enable to detect a disease much earlier that is currently possible.

Deliverables

List of deliverables.
First designs of potential RF coil systems with metamaterials from WP3-5	Documents, reports	2020-03-25 16:29:32
Interim Plan for Dissemination and exploiting project results	Documents, reports	2020-03-25 16:29:32
CAD-models of metasurface samples and metasurface-based RF devices	Other	2020-03-25 16:29:32
Description of a newly developed software analysis tool, and a report describing quantitatively the effect of pre-selected metamaterials on MRI fields	Documents, reports	2020-03-25 16:29:32
Comparative study of metasurfaces stressed on MRI applications	Documents, reports	2020-03-25 16:29:33
Version of M-Cube Website online and Communication materials	Documents, reports	2020-03-25 16:29:32
Data Management Plan	Open Research Data Pilot	2020-03-25 16:29:32
Definition of the metrics and the fundamental survey on hybridized antenna	Documents, reports	2020-03-25 16:29:33
First MRI experiments with RF coil systems from D5.2 have been performed	Documents, reports	2020-03-25 16:29:32
Realization of first designs from D6.1 with the required system hardware, phantoms, and test procedure	Documents, reports	2020-03-25 16:29:32
Risk study report related to every coil prototypes before submission to national ethical authorities. This deliverable will include k-factor or q-matrices calculations	Documents, reports	2020-03-25 16:29:33
Report on 3 or 4 different types of metamaterials and the possible advantages that they could bring to whole-body MRI diagnosis. Ranking among those metamaterials	Documents, reports	2020-03-25 16:29:32

Take a look to the deliverables list in detail: detailed list of M-CUBE deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Marine A. C. Moussu, Luisa Ciobanu, Sergej Kurdjumov, Elizaveta Nenasheva, Boucif Djemai, Marc Dubois, Andrew G. Webb, Stefan Enoch, Pavel Belov, Redha Abdeddaim, Stanislav Glybovski Systematic Analysis of the Improvements in Magnetic Resonance Microscopy with Ferroelectric Composite Ceramics published pages: 1900912, ISSN: 0935-9648, DOI: 10.1002/adma.201900912	Advanced Materials	2020-03-25
2019	Kaizad Rustomji, Marc Dubois, Boris Kuhlmey, C. Martijn de Sterke, Stefan Enoch, Redha Abdeddaim, JÃ©rÃ´me Wenger Direct Imaging of the Energy-Transfer Enhancement between Two Dipoles in a Photonic Cavity published pages: , ISSN: 2160-3308, DOI: 10.1103/PhysRevX.9.011041	Physical Review X 9/1	2020-03-25
2019	Tania S. Vergara Gomez, Marc Dubois, Stanislav Glybovski, Benoit Larrat, Julien Rosny, Carsten Rockstuhl, Monique Bernard, Redha Abdeddaim, Stefan Enoch, Frank Kober Wireless coils based on resonant and nonresonant coupledâ€wire structure for small animal multinuclear imaging published pages: e4079, ISSN: 0952-3480, DOI: 10.1002/nbm.4079	NMR in Biomedicine 32/5	2020-03-25
2019	Masoud Sharifian Mazraeh Mollaei, Sergei Alexandrovich Kurdjumov, Anna Aleksandrovna Hurshkainen, Constantin Rufovich Simovski DECOUPLING OF TWO CLOSELY LOCATED DIPOLES BY A SINGLE PASSIVE SCATTERER FOR ULTRA-HIGH FIELD MRI published pages: 155-166, ISSN: 1559-8985, DOI: 10.2528/PIER18101703	Progress In Electromagnetics Research 164	2020-03-25
2017	Sergei Kurdjumov, Stanislav Glybovski, Anna Hurshkainen, Andrew Webb, Redha Abdeddaim, Luisa Ciobanu, Irina Melchakova, Pavel Belov A mechanically tunable and efficient ceramic probe for MR-microscopy at 17 Tesla published pages: 30011, ISSN: , DOI: 10.1063/1.4998040	AIP Conference Proceedings volume 1883	2020-03-25
2018	M. Sharifian Mazraeh Mollaei, A. Hurshkainen, S. Kurdjumov, S. Glybovski, Constantin Simovski Decoupling of Two Closely Located Dipole Antennas by a Split-Loop Resonator published pages: , ISSN: 0048-6604, DOI: 10.1029/2018rs006679	Radio Science	2020-03-25
2018	Anna Hurshkainen, Anton Nikulin, Elodie Georget, Benoit Larrat, Djamel Berrahou, Ana Luisa Neves, Pierre Sabouroux, Stefan Enoch, Irina Melchakova, Pavel Belov, Stanislav Glybovski, Redha Abdeddaim A Novel Metamaterial-Inspired RF-coil for Preclinical Dual-Nuclei MRI published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-27327-y	Scientific Reports 8/1	2020-03-25
2018	Georgiy Solomakha, Carel van Leeuwen, Alexander Raaijmakers, Constantin Simovski, Alexander Popugaev, Redha Abdeddaim, Irina Melchakova, Stanislav Glybovski The dual-mode dipole: A new array element for 7T body imaging with reduced SAR published pages: , ISSN: 0740-3194, DOI: 10.1002/mrm.27485	Magnetic Resonance in Medicine	2020-03-25
2018	M. S.M. Mollaei, A. Hurshkainen, S. Kurdjumov, S. Glybovski, C. Simovski Passive electromagnetic decoupling in an active metasurface of dipoles published pages: 53-61, ISSN: 1569-4410, DOI: 10.1016/j.photonics.2018.10.001	Photonics and Nanostructures - Fundamentals and Applications 32	2020-03-25
2018	Marc Dubois, Lisa Leroi, Zo Raolison, Redha Abdeddaim, Tryfon Antonakakis, Julien de Rosny, Alexandre Vignaud, Pierre Sabouroux, Elodie Georget, Benoit Larrat, GÃ©rard Tayeb, Nicolas Bonod, Alexis Amadon, Franck Mauconduit, Cyril Poupon, Denis Le Bihan, Stefan Enoch Kerker Effect in Ultrahigh-Field Magnetic Resonance Imaging published pages: All, ISSN: 2160-3308, DOI: 10.1103/PhysRevX.8.031083	Physical Review X 8/3	2020-03-25
2018	Mikhail Zubkov, Anna A. Hurshkainen, Ekaterina A. Brui, Stanislav B. Glybovski, Mikhail V. Gulyaev, Nikolai V. Anisimov, Dmitry V. Volkov, Yury A. Pirogov, Irina V. Melchakova Small-animal, whole-body imaging with metamaterial-inspired RF coil published pages: e3952, ISSN: 0952-3480, DOI: 10.1002/nbm.3952	NMR in Biomedicine 31/8	2020-03-25
2018	M Zubkov, A A Hurshkainen, E A Brui, S B Glybovski, M V Gulyaev, N V Anisimov, D V Volkov, Y A Pirogov, I V Melchakova Small animal large field of view magnetic resonance imaging with metamaterial-inspired resonator published pages: 12180, ISSN: 1742-6588, DOI: 10.1088/1742-6596/1092/1/012180	Journal of Physics: Conference Series 1092	2020-03-25
2018	G. Solomakha, S. Glybovski, R. Abbdedaim, C. Simovski, I. Melchakova A Radiofrequency Coil Based on Hybridized Modes Two Resonant Dipoles published pages: 12142, ISSN: 1742-6588, DOI: 10.1088/1742-6596/1092/1/012142	Journal of Physics: Conference Series 1092	2020-03-25
2018	Ana L. Neves, Lisa Leroi, Zo Raolison, Nicolas Cochinaire, Thibaut Letertre, Redha AbdeddaÃ¯m, Stefan Enoch, Jerome Wenger, Johann Berthelot, Anne-Lise Adenot-Engelvin, Nicolas MallÃ©jac, Franck Mauconduit, Alexandre Vignaud, Pierre Sabouroux Compressed perovskite aqueous mixtures near their phase transitions show very high permittivities: New prospects for high-field MRI dielectric shimming published pages: 1753-1765, ISSN: 0740-3194, DOI: 10.1002/mrm.26771	Magnetic Resonance in Medicine 79/3	2020-03-25

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