Opendata, web and dolomites

BIONICS SIGNED

A biomimetic and neuroprotective delivery nanocapsule for the targeted treatment of post-ischemic stroke effects

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 BIONICS project word cloud

Explore the words cloud of the BIONICS project. It provides you a very rough idea of what is the project "BIONICS" about.

nanoparticles    oxidative    microfluidic    skills    seminars    nanocapsules    fabrication    reducing    treatment    stress    blockage    writing    antioxidant    permanent    date    showed    region       workshops    rns    caused    impending    percentages    overproduction    death    biology    limited    synthesis    lipid    pathogenesis    ing    models    prevent    presented    oxidant    ischemic    closer    iit    transferable    molecular    acquire    action    ceo2    total    overproduced    thought    countries    independent    million    first    nanocapsule    career    market    safely    post    unfortunately    amelioration    inos    biomimetic    63    neuroprotective    worldwide    expertise    inhibitors    believe    ros    transfer    bbb    2034    me    opportunity    mortality    techniques    43    found    occurs    blood    stroke    deficits    gained    mmp    vessel    brain    give    damage    neurological    plans    incidents    nil    researcher    bionics    goals    morbidity    therapeutic    anti    treatments    perfusion    grant   

Project "BIONICS" data sheet

The following table provides information about the project.

Coordinator
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA 

Organization address
address: VIA MOREGO 30
city: GENOVA
postcode: 16163
website: www.iit.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 168˙277 €
 EC max contribution 168˙277 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-05-01   to  2020-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA IT (GENOVA) coordinator 168˙277.00

Map

 Project objective

Ischemic stroke occurs due to reduced perfusion to a brain region, because of the blockage of a blood vessel, resulting in death or permanent neurological deficits. It presents high percentages of mortality and morbidity worldwide and market analysis in five major EU countries showed that the total number of first-ever incidents of stroke cases will rise to 1.63 million (43.7% growth) by 2034. Although, many treatments that make use of therapeutic nanoparticles have been presented, unfortunately to date, no effective treatment has been found to prevent damage to the ischemic brain after stroke. Oxidative stress is related to the pathogenesis of stroke and overproduction of ROS and RNS are thought to be the main cause of this. In addition, the overproduction of MMP-9 has been related to many post-stroke side effects. Thus, I propose the development of a biomimetic and neuroprotective lipid nanocapsule (BIONICS) for the targeted treatment of post-stroke side effects. BIONICS will safely deliver anti-oxidant nanoparticles (CeO2) and iNOS inhibitors (L-NIL) across the BBB aiming at reducing the overproduced ROS, RNS and MMP-9, resulting in to the amelioration of the neurological deficits caused by oxidative stress. Through this project, the new skills in the synthesis of antioxidant nanocapsules, the use of molecular biology techniques, design and fabrication of microfluidic models, project management, grant writing, and other transferable skills that I will acquire in IIT, will help my future career plans providing knowledge and expertise in a field where my knowledge is limited. This action will also give me the opportunity to transfer my pre-gained knowledge through seminars/workshops to the institution where my research will be carried out. Overall, I believe that BIONICS will have a significant impact on my short and long-term career goals and will bring me one step closer to my impending goal of the independent researcher.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "BIONICS" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "BIONICS" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

TheaTheor (2018)

Theorizing the Production of 'Comedia Nueva': The Process of Play Configuration in Spanish Golden Age Theater

Read More  

InBPSOC (2020)

Increases biomass production and soil organic carbon stocks with innovative cropping systems under climate change

Read More  

GENI (2019)

Gender, emotions and national identities: a new perspective on the abortion debates in Italy (1971-1981).

Read More