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HI-SiMed TERMINATED

Hemodynamics in an Infarcted heart: from multi-physics Simulations to Medical analysis

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 HI-SiMed project word cloud

Explore the words cloud of the HI-SiMed project. It provides you a very rough idea of what is the project "HI-SiMed" about.

tissue    dynamics    elastic    animated    cellular    close    diseases    deformation    cycle    mechanics    twente    building    computational    university    propagation    mature    sex    functioning    accurate    electro    provides    pulsatile    ing    accounting    improvement    ut    code    correlate    fundamental    place    surgeons    tool    blood    model    physics    reproduced    wave    capture    science    structure    surrounding    fluids    biological    caused    framework    models    nowadays    quantitative    community    generates    collaborating    circulation    outcomes    modify    fluid    mechanical    stresses    myocardium    medical    topology    heart    reproduce    innovative    structures    treatment    neglecting    physiology    location    relaxation    pumping    functional    electrical    pof    aorta    flow    vorticity    group    ventricle    hemodynamics    differences    left    vortex    electrophysiology    principal    propels    cardiac    contraction    systemic    infarction    simed    hi    connecting    horizons    cooperation    human   

Project "HI-SiMed" data sheet

The following table provides information about the project.

Coordinator		 UNIVERSITEIT TWENTE 

Organization address
address: DRIENERLOLAAN 5
city: ENSCHEDE
postcode: 7522 NB
website: www.utwente.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Netherlands [NL]
 Total cost 165˙598 €
 EC max contribution 165˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-09-01   to  2021-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 165˙598.00

Map

 Project objective

The left ventricle is the principal mechanical element of the human heart that propels blood to the systemic circulation. Its contraction is the result of an electrical wave propagation generated at the cellular level and is studied in the framework of cardiac electrophysiology. This science is nowadays mature and provides models to capture and reproduce the contraction/relaxation cycle of the heart that are used for a quantitative understanding of the heart functioning. However, these electrophysiology models do not include the hemodynamics caused by the ventricle deformation, thus neglecting the fundamental vortex dynamics taking place in the heart physiology, which generates stresses on the surrounding cardiac tissue. This project aims at connecting the electrophysiology and the fluid mechanics building an electro-fluid-structure computational model for the pulsatile flow in an animated left ventricle and elastic aorta. Biological heart conditions will be reproduced as close as possible by merging my electrophysiology code with the advanced fluid-structure framework of the Physics of Fluids group (PoF) at University of Twente (UT). The resulting multi-physics model will allow studying the accurate hemodynamics and cardiac tissue stresses generated in an animated ventricle. Building on my experience in vortex dynamics, we will correlate the topology of the vorticity structures with the heart functional pumping and then study how cardiac diseases such as myocardium infarction modify them, accounting for infarction location and sex differences. The outcomes of HI-SiMed will provide the medical community with an innovative and advanced tool that could open new horizons for the improvement of treatment outcomes. With this ambitious aim, the project will be developed in close cooperation with the cardiac surgeons already collaborating with the PoF.

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The information about "HI-SIMED" are provided by the European Opendata Portal: CORDIS opendata.

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