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2STOP_TBE SIGNED

Structural Openings to Understand and Prevent Tick Borne Encephalitis

Total Cost €

EC-Contrib. €

Partnership

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2STOP_TBE project word cloud

Explore the words cloud of the 2STOP_TBE project. It provides you a very rough idea of what is the project "2STOP_TBE" about.

neurological rate powerful efforts encephalitis uncertain assembly virus tick revealing lack morphogenesis infections care virology treatments harness diagnostic fill drug hampered medications tbev spread fundamental structural detection push gap life contract producing impactful structure expertise market disease questions largely tbe rates seek causes health answer individuals cryo excellence incidence borne function mortality discovery vaccine explicit microscopy atomic critical viruses viral becomes biology details electron regarding societal surprising environmental diagnostics threat limited

Project "2STOP_TBE" data sheet

The following table provides information about the project.

Coordinator	HELSINGIN YLIOPISTO Organization address address: YLIOPISTONKATU 3 city: HELSINGIN YLIOPISTO postcode: 14 website: www.helsinki.fi contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Finland [FI]
Total cost	179˙325 €
EC max contribution	179˙325 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2017
Funding Scheme	MSCA-IF-EF-ST
Starting year	2018
Duration (year-month-day)	from 2018-05-18 to 2020-05-17

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	HELSINGIN YLIOPISTO HELSINGIN YLIOPISTO Organization address address: YLIOPISTONKATU 3 city: HELSINGIN YLIOPISTO postcode: 14 website: www.helsinki.fi contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (HELSINGIN YLIOPISTO)	coordinator	179˙325.00

Map

Project objective

Tick-borne encephalitis virus (TBEV) is emerging in Europe. It causes tick-borne encephalitis (TBE), a disease with a high mortality rate and even higher rates of life-long neurological effects in individuals that contract infections. As environmental and societal changes promote viral spread and current vaccine use is limited, it is not surprising that TBE incidence is on the rise. With uncertain diagnostics and no medications on the market, the threat to European health care becomes significant, making development of control measures a high priority.

Efforts to develop treatments and improve detection are largely hampered by a lack of structural knowledge about TBEV. Here we seek to fill the critical information gap, using electron cryo-microscopy, which has become a powerful technology for revealing atomic-level details about viruses. We will harness unique expertise in the fields of virology and structural biology to answer fundamental questions about virus structure, assembly, morphogenesis, and function. Explicit new knowledge regarding TBEV will push forward European excellence in virus research producing impactful results for their exploitation in drug discovery and diagnostic developments.

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The information about "2STOP_TBE" are provided by the European Opendata Portal: CORDIS opendata.