REGENERA SIGNED
Helping cancer survivors restoring their natural breast with resorbable implants inducing selfâ€tissue regeneration
Total Cost €
0EC-Contrib. €
0Partnership
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0REGENERA project word cloud
Explore the words cloud of the REGENERA project. It provides you a very rough idea of what is the project "REGENERA" about.
Project "REGENERA" data sheet
The following table provides information about the project.
| Coordinator |
TENSIVE SRL
Organization address contact info |
| Coordinator Country | Italy [IT] |
| Project website | https://www.regenerabreast.com/ |
| Total cost | 2˙698˙813 € |
| EC max contribution | 1˙889˙169 € (70%) |
| Programme |
1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies) |
| Code Call | H2020-SMEInst-2018-2020-2 |
| Funding Scheme | SME-2 |
| Starting year | 2018 |
| Duration (year-month-day) | from 2018-06-01 to 2020-05-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | TENSIVE SRL | IT (MILANO) | coordinator | 1˙889˙169.00 |
Map
Project objective
Tensive was founded in 2012 to address the challenge of developing better biomaterials for regenerative medicine. We developed a bio absorbable scaffold based on highly biocompatible polyurethaneester. Our patented scaffolds provide a synthetic micro-vascular network that enables adipocytes colonization in vivo. This unique design leads to vascularization, fat integration and volume maintaining after implantation. Based on these unique properties, we will bring to the market REGENERA, an innovative mammary prosthesis that is degraded over time and replaced by the patient´s fat. Silicone implants, the most currently used breast tissue modifications, have important risks and need replacement every 10-15 years. Fat grafting, the best alternative nowadays, has been linked to carcinogenic risks and does not promote vascularization (leading to necrosis) with multiple interventions needed for large reconstructions. REGENERA, which only requires one surgical intervention, will meet the need to develop biomaterials able to promote new blood vessels formation that perpetuate the reconstructed tissue. REGENERA will have a significant impact on various levels: (i) Healthcare system: it will save the cost of additional surgeries (more than €241M yearly in the EU), helping to the sustainability of the Healthcare system. (ii) breast cancer patients: it will offer a solution to lumpectomy patients, for whom there are no good solutions yet; a better alternative for mastectomy and breast augmentation patients; a permanent solution by a single surgery for all patients, improving their quality of life. (iii) company: it will increase Tensive’s revenues (cumulative profit of €257M with a ROI of 19.37 by 2025) (iv) society: it will highly benefit 230,000 women needing reconstructive surgery after breast cancer, together with the 1.35M women undergoing breast augmentation for personal reasons
Deliverables
| Web page of the project | Documents, reports | 2019-10-01 09:19:20 |
Take a look to the deliverables list in detail: detailed list of REGENERA deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2018 |
Eleonora Rossi, Julien Guerrero, Paola Aprile, Alessandro Tocchio, Elisabeth A. Kappos, Irini Gerges, Cristina Lenardi, Ivan Martin, Arnaud Scherberich Decoration of RGD-mimetic porous scaffolds with engineered and devitalized extracellular matrix for adipose tissue regeneration published pages: 154-166, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2018.04.039 |
Acta Biomaterialia 73 | 2019-08-30 |
| 2018 |
Irini Gerges, Margherita Tamplenizza, Federico Martello, Camilla Recordati, Cristina Martelli, Luisa Ottobrini, Mariacaterina Tamplenizza, Scott A. Guelcher, Alessandro Tocchio, Cristina Lenardi Exploring the potential of polyurethane-based soft foam as cell-free scaffold for soft tissue regeneration published pages: 141-153, ISSN: 1742-7061, DOI: 10.1016/j.actbio.2018.04.011 |
Acta Biomaterialia 73 | 2019-08-30 |
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