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TIMB3 SIGNED

Twin to Illuminate Metals in Biology and Biocatalysis through Biospectroscopy

Total Cost €

EC-Contrib. €

Partnership

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TIMB3 project word cloud

Explore the words cloud of the TIMB3 project. It provides you a very rough idea of what is the project "TIMB3" about.

metals actions bilateral compete runs tub events catalysis bioinspired highest group create underlying iron enhancement broadening itqb solutions biology infrastructure environmental specialists intensive establishing versatile timb3 soft skills profile international exchange nova networking narrower capitalize raised scientific transform notwithstanding fide capacity biotechnological staff missions metal writing think opportunity capacities human virtual theme cirmmp italy instruments ip league structured world combination public platform radically blood trafficking successful counterparts performing portugal social bona training enter integration homeostasis biospectroscopy health germany emerges offers appreciation itself class pressing

Project "TIMB3" data sheet

The following table provides information about the project.

Coordinator	UNIVERSIDADE NOVA DE LISBOA Organization address address: CAMPUS DE CAMPOLIDE city: LISBOA postcode: 1099 085 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Portugal [PT]
Total cost	994˙367 €
EC max contribution	994˙367 € (100%)
Programme	1. H2020-EU.4.b. (Twinning of research institutions)
Code Call	H2020-WIDESPREAD-05-2017-Twinning
Funding Scheme	CSA
Starting year	2018
Duration (year-month-day)	from 2018-09-01 to 2021-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSIDADE NOVA DE LISBOA UNIVERSIDADE NOVA DE LISBOA Organization address address: CAMPUS DE CAMPOLIDE city: LISBOA postcode: 1099 085 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PT (LISBOA)	coordinator	687˙500.00
2	TECHNISCHE UNIVERSITAT BERLIN TECHNISCHE UNIVERSITAT BERLIN Organization address address: STRASSE DES 17 JUNI 135 city: BERLIN postcode: 10623 website: www.tu-berlin.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERLIN)	participant	164˙375.00
3	CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE Organization address address: PIAZZA SAN MARCO 4 city: FIRENZE postcode: 50121 website: www.cerm.unifi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (FIRENZE)	participant	142˙492.00

Map

Project objective

TIMB3 offers the unique opportunity to capitalize on the existing infrastructure and human resources of ITQB-NOVA (Portugal) on biospectroscopy applied to the study of metals in biology to raise its scientific profile and achieve integration in the top league of research intensive institutions. The essential role of metals in biology is well recognized even by the general public (think of iron in blood). Notwithstanding, there is a growing appreciation of the potential of their study to radically transform our capacity to improve health and well-being and to develop novel biotechnological solutions to pressing environmental problems. This project emerges from successful test runs with the world class partners CIRMMP (Italy) and TUB (Germany), using networking instruments of narrower reach such as COST actions and bilateral partnerships. The scientific theme underlying the execution of TIMB3 is the enhancement of the capacity of ITQB-NOVA in performing world class research in biospectroscopy applied to metal homeostasis and trafficking and applied to bioinspired catalysis. The research profile of ITQB-NOVA staff will be raised by a combination of exchange missions with counterparts on the partner institutions, and structured training events on scientific and soft skills, including project writing and IP awareness. These activities will enable ITQB-NOVA to create a virtual platform for biospectroscopy to be used by non-specialists to learn the potential of this versatile group of methods to solve their specific research and development problems, broadening the social awareness to the capacities of biospectroscopy applied to the study of metals in biology. At the end of TIMB3, ITQB-NOVA will be able to enter international scientific consortia and compete for funding at the highest level establishing itself as a bona fide member of the top league of research intensive institutions.

Publications

List of publications.
year	authors and title	journal	last update
2020	Panagis Polykretis, Enrico Luchinat, Francesca Boscaro, Lucia Banci Methylglyoxal interaction with superoxide dismutase 1 published pages: 101421, ISSN: 2213-2317, DOI: 10.1016/j.redox.2019.101421	Redox Biology 30	2020-02-06
2019	Yulia Ilina, Christian Lorent, Sagie Katz, Jae-Hun Jeoung, Seigo Shima, Marius Horch, Ingo Zebger, Holger Dobbek X-ray Crystallography and Vibrational Spectroscopy Reveal the Key Determinants of Biocatalytic Dihydrogen Cycling by [NiFe] Hydrogenases published pages: 18710-18714, ISSN: 1433-7851, DOI: 10.1002/anie.201908258	Angewandte Chemie International Edition 58/51	2020-02-06
2019	Veronica Nasta, Stefano Da Vela, Spyridon Gourdoupis, Simone Ciofi-Baffoni, Dmitri I. Svergun, Lucia Banci Structural properties of [2Fe-2S] ISCA2-IBA57: a complex of the mitochondrial iron-sulfur cluster assembly machinery published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-019-55313-5	Scientific Reports 9/1	2020-02-06
2019	Karim Zuhra, Catarina S. TomÃ©, Letizia Masi, Giorgio Giardina, Giulia Paulini, Francesca MalagrinÃ², Elena Forte, JoÃ£o B. Vicente, Alessandro GiuffrÃ¨ N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells published pages: 828, ISSN: 2073-4409, DOI: 10.3390/cells8080828	Cells 8/8	2020-02-05
2019	Estelle LebÃ¨gue, Nazua L. Costa, Bruno M. Fonseca, Ricardo O. Louro, FrÃ©dÃ©ric BarriÃ¨re Electrochemical properties of pH-dependent flavocytochrome c3 from Shewanella putrefaciens adsorbed onto unmodified and catechol-modified edge plane pyrolytic graphite electrode published pages: 113232, ISSN: 1572-6657, DOI: 10.1016/j.jelechem.2019.113232	Journal of Electroanalytical Chemistry 847	2020-02-05
2019	Catarina G. Fernandes, Diogo Martins, Guillem Hernandez, Ana L. Sousa, Carolina Freitas, Erin M. Tranfield, Tiago N. Cordeiro, MÃ³nica Serrano, Charles. P. Moran, Adriano O. Henriques Temporal and spatial regulation of protein cross-linking by the pre-assembled substrates of a Bacillus subtilis spore coat transglutaminase published pages: e1007912, ISSN: 1553-7404, DOI: 10.1371/journal.pgen.1007912	PLOS Genetics 15/4	2019-12-16
2019	Marco A. M. Videira, Susana A. L. Lobo, Filipa L. Sousa, LÃgia M. Saraiva Identification of the sirohaem biosynthesis pathway in StaphylococcusÂ aureus published pages: , ISSN: 1742-464X, DOI: 10.1111/febs.15091	The FEBS Journal	2019-12-16
2019	Melanie Miller, William E. Robinson, Ana Rita Oliveira, Nina Heidary, Nikolay Kornienko, Julien Warnan, InÃªs A. C. Pereira, Erwin Reisner Interfacing Formate Dehydrogenase with Metal Oxides for the Reversible Electrocatalysis and Solar-Driven Reduction of Carbon Dioxide published pages: 4601-4605, ISSN: 1433-7851, DOI: 10.1002/anie.201814419	Angewandte Chemie International Edition 58/14	2019-12-16
2019	N. L. Costa, B. Hermann, V. Fourmond, M. M. Faustino, M. Teixeira, O. Einsle, C. M. Paquete, R. O. Louro How Thermophilic Gram-Positive Organisms Perform Extracellular Electron Transfer: Characterization of the Cell Surface Terminal Reductase OcwA published pages: , ISSN: 2150-7511, DOI: 10.1128/mbio.01210-19	mBio 10/4	2019-12-16
2019	Sandra M. Carvalho, Joana Marques, Carlos C. RomÃ£o, LÃgia M. Saraiva Metabolomics of Escherichia coli Treated with the Antimicrobial Carbon Monoxide-Releasing Molecule CORM-3 Reveals Tricarboxylic Acid Cycle as Major Target published pages: , ISSN: 0066-4804, DOI: 10.1128/aac.00643-19	Antimicrobial Agents and Chemotherapy 63/10	2019-12-16
2019	Veronica Palma Delgado, Catarina M. Paquete, Gunnar Sturm, Johannes Gescher Improvement of the electron transfer rate in Shewanella oneidensis MR-1 using a tailored periplasmic protein composition published pages: 18-25, ISSN: 1567-5394, DOI: 10.1016/j.bioelechem.2019.04.022	Bioelectrochemistry 129	2019-12-16
2019	SÃ³nia Zacarias, Adriana TemporÃ£o, Melisa del Barrio, Vincent Fourmond, Christophe LÃ©ger, Pedro M. Matias, InÃªs A. C. Pereira A Hydrophilic Channel Is Involved in Oxidative Inactivation of a [NiFeSe] Hydrogenase published pages: 8509-8519, ISSN: 2155-5435, DOI: 10.1021/acscatal.9b02347	ACS Catalysis 9/9	2019-12-17
2019	Sandra P. Santos, Yang Yang, Margarida T. G. Rosa, Mafalda A. A. Rodrigues, Claire Bouthier De La Tour, Suzanne Sommer, Miguel Teixeira, Maria A. Carrondo, Peter Cloetens, Isabel A. Abreu, CÃ©lia V. RomÃ£o The interplay between Mn and Fe in Deinococcus radiodurans triggers cellular protection during paraquat-induced oxidative stress published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-019-53140-2	Scientific Reports 9/1	2019-12-16
2019	Maria C. Martins, CÃ©lia V. RomÃ£o, Filipe Folgosa, PatrÃcia T. Borges, Carlos FrazÃ£o, Miguel Teixeira How superoxide reductases and flavodiiron proteins combat oxidative stress in anaerobes published pages: 36-60, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2019.01.051	Free Radical Biology and Medicine 140	2019-12-16
2019	Karim Zuhra, Catarina S. TomÃ©, Letizia Masi, Giorgio Giardina, Giulia Paulini, Francesca MalagrinÃ², Elena Forte, JoÃ£o B. Vicente, Alessandro GiuffrÃ¨ N-Acetylcysteine Serves as Substrate of 3-Mercaptopyruvate Sulfurtransferase and Stimulates Sulfide Metabolism in Colon Cancer Cells published pages: 828, ISSN: 2073-4409, DOI: 10.3390/cells8080828	Cells 8/8	2019-12-16
2018	AmÃ©rico G. Duarte, Teresa Catarino, Gaye F. White, Diana Lousa, Sinje Neukirchen, ClÃ¡udio M. Soares, Filipa L. Sousa, Thomas A. Clarke, InÃªs A. C. Pereira An electrogenic redox loop in sulfate reduction reveals a likely widespread mechanism of energy conservation published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-07839-x	Nature Communications 9/1	2019-03-18
2018	Liliana S. O. Silva, Joana M. Baptista, Charlotte Batley, Simon C. Andrews, LÃgia M. Saraiva The Di-iron RIC Protein (YtfE) of Escherichia coli Interacts with the DNA-Binding Protein from Starved Cells (Dps) To Diminish RIC Protein-Mediated Redox Stress published pages: , ISSN: 0021-9193, DOI: 10.1128/jb.00527-18	Journal of Bacteriology 200/24	2019-03-18

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