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EvoConBiO SIGNED

Uncovering and engineering the principles governing evolution and cellular control of bioenergetic organelles

Total Cost €

0

EC-Contrib. €

0

Partnership

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 EvoConBiO project word cloud

Explore the words cloud of the EvoConBiO project. It provides you a very rough idea of what is the project "EvoConBiO" about.

retained    combining    robustness    transferring    genetic    organelles    points    edge    principles    rational    agriculture    direction    reveal    bioengineering    reward    plants    combination    history    engineer    experiment    modern    earth    organisms    powered    first    poorly    integrity    structure    universal    maintenance    originally    bioenergetic    performance    evolution    central    cutting    uncovering    theory    algae    akin    time    ecosystem    adapt    life    dramatically    retaining    manipulation    maintaining    dynamic    mathematical    characterisation    drive    nucleus    experimental    strategies    sky    questions    eukaryotic    chloroplast    interdisciplinary    organelle    scientific    independent    chloroplasts    mtdna    harness    co    content    populations    genomes    genes    blue    cells    groundbreaking    statistics    form    cellular    shaping    cpdna    tension    evolutionary    resolve    insights    individuals    risk    day    underlying    evoconbio    suggests    biofuel    mitochondria    unprecedented   

Project "EvoConBiO" data sheet

The following table provides information about the project.

Coordinator		 UNIVERSITETET I BERGEN 

Organization address
address: MUSEPLASSEN 1
city: BERGEN
postcode: 5020
website: www.uib.no

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Norway [NO]
 Total cost 1˙417˙862 €
 EC max contribution 1˙417˙862 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2024-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITETET I BERGEN NO (BERGEN) coordinator 1˙417˙862.00
2    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) participant 0.00

Map

 Project objective

'Complex life on Earth is powered by bioenergetic organelles -- mitochondria and chloroplasts. Originally independent organisms, these organelles have retained their own genomes (mtDNA and cpDNA), which have been dramatically reduced through evolutionary history. Organelle genomes form dynamic populations within present-day eukaryotic cells, akin to individuals co-evolving in a 'cellular ecosystem'. The structure of these populations is central to eukaryotic life. However, the processes shaping the content of these genomes through history, and maintaining their integrity in modern organisms, are poorly understood. This challenges our understanding of eukaryotic evolution and our ability to design rational strategies to engineer bioenergetic performance.

EvoConBiO will address these questions using a unique and unprecedented interdisciplinary approach, combining experimental characterisation and manipulation of organelle genomes with mathematical modelling and cutting-edge statistics. This highly novel combination of experiment and theory will drive the field in a new direction, for the first time uncovering the universal principles underlying the evolution and cellular control of mitochondria and chloroplasts. Our groundbreaking recent work on mtDNA suggests a common tension underlying organelle evolution, between genetic robustness (transferring genes to the nucleus) and the control and maintenance of organelles (retaining genes in organelles). EvoConBiO will reveal the pathways underlying organelle evolution, why organisms adapt to different points on these pathways, and how they resolve this underlying tension. In addition to these 'blue sky' scientific insights into a process of central evolutionary importance, we will harness our findings to 'learn from evolution' in high-risk high-reward development of new experimental strategies to engineer chloroplast performance in plants and algae of importance in EU agriculture, biofuel production, and bioengineering.'

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The information about "EVOCONBIO" are provided by the European Opendata Portal: CORDIS opendata.

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