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SEPSCAV SIGNED

SCAVENGING ON SEPSIS. DEVELOPMENT OF SEPSIS SPECIFIC DRUGS FROM HUMAN SCAVENGER RECEPTORS

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

SEPSCAV project word cloud

Explore the words cloud of the SEPSCAV project. It provides you a very rough idea of what is the project "SEPSCAV" about.

combined infections market cardiovascular inhibits organ fungal human caused dual start life claims interact derivatives proteins antibiotic syndrome toxins receptors pro neutralize protects inflammatory naturally therapeutics structural bactericidal manner cancer blocks sepsis lives entry components mode lymphocyte collapse holds inflammation action anti adjunctive strategy dose microbes dependent cd6 experimental septic occurring injectable death sixtide breast sepsia dysfunction treatment spectrum scavenger mice disorders core threatening therapeutic alternative receptor mods peptide blood cells limited time ipr drug infection company bowel bacterial shock

Project "SEPSCAV" data sheet

The following table provides information about the project.

Coordinator	SEPSIA THERAPEUTICS SL Organization address address: PLAZA EUROPA NUM 9 11 PLANTA 13 TORRE INBISA city: L HOSPITALET DE LLOBREGAT postcode: 8908 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Project website	http://www.sepsia.com
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-SMEInst-2018-2020-1
Funding Scheme	SME-1
Starting year	2019
Duration (year-month-day)	from 2019-02-01 to 2019-07-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	SEPSIA THERAPEUTICS SL SEPSIA THERAPEUTICS SL Organization address address: PLAZA EUROPA NUM 9 11 PLANTA 13 TORRE INBISA city: L HOSPITALET DE LLOBREGAT postcode: 8908 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (L HOSPITALET DE LLOBREGAT)	coordinator	50˙000.00

Map

Project objective

Sepsis is a major a life-threatening condition caused by bacterial or fungal infections leading to cardiovascular collapse (septic shock), multi-organ dysfunction syndrome (MODS) and death, and claims more lives that bowel and breast cancer combined. The human Scavenger-receptors are naturally occurring proteins on some blood cells that interact and neutralize core structural components of microbes, providing a novel therapeutic strategy for wide-spectrum sepsis treatment and an alternative to current antibiotic and adjunctive therapeutic approaches of limited success. Sepsia Therapeutics is a R&D start up company developing SIXTIDE, a peptide-drug based on human scavenger lymphocyte receptor CD6, with dual bactericidal and anti-inflammatory action, which protects mice from death in experimental sepsis, in a time- and dose-dependent manner. SIXTIDE mode of action inhibits bacterial growth and blocks the pro-inflammatory properties of bacterial toxins. Sepsia Therapeutics holds IPR on the use of CD6 and CD6 derivatives in the treatment of infection and inflammation disorders and aims for market entry through injectable SIXTIDE.

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The information about "SEPSCAV" are provided by the European Opendata Portal: CORDIS opendata.