The page lists 191 projects related to the topic "dysfunction".
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1 | ImmunoAgeing | An integrated approach to dissect determinants, risk factors and pathways of ageing of the immune system. | 2015 |
2 | RevMito | Deciphering and reversing the consequences of mitochondrial DNA damage | 2015 |
3 | NOVA | Non-coding RNA in Vascular Ageing | 2015 |
4 | CorticALS | Amyotrophic Lateral Sclerosis from a cortical perspective: towards alternative therapeutic strategies | 2015 |
5 | TheLiRep | Exploring the Potential for Therapeutic Lineage Reprogramming of Diabetes | 2015 |
6 | NextGenVis | Training the Next Generation of European Visual Neuroscientists for the benefit of innovation in health care and high-tech industry | 2015 |
7 | PeroxiSystem | Systematic exploration of peroxisomal structure and function | 2015 |
8 | LYMPHORG | Organ-specific mechanisms of lymphatic vascular development and specialisation | 2015 |
9 | MITOsmORFs | Identification and analysis of novel mitochondrial proteins encoded by small open reading frames | 2015 |
10 | iMUC | Improving the Management of Unexplained Chest-pain | 2014 |
11 | MitSyn | Alpha-synuclein and mitochondrial dysfunction: key links between Gaucher’s disease and Parkinson’s? | 2015 |
12 | OTULINVIVO | The role of OTULIN and Met1-linked ubiquitin in immune signaling and host defense in vivo | 2015 |
13 | DecoMP_ECoG | Decoding memory processing from experimental and spontaneous human brain activity using intracranial electrophysiological recordings and machine learning based methods. | 2015 |
14 | GLUCOTOX | Does reducing β-cell glucotoxicity increase the hyperglycaemia-lowering effect of physical exercise in type 2 diabetes? | 2015 |
15 | AfterTheIce | After the Ice: using a hybrid zone as a window into the genes underlying species formation | 2015 |
16 | HEALTHYSYNAPSES | Molecular mechanisms underlying synaptic maintenance and rejuvenation | 2016 |
17 | Magnetic HEART | Targeting the Human Myocardial Remodeling Process Using Novel Magnetic Force-Based Human Heart Tissue | 2016 |
18 | NEURINFDNA | Neuronal DNA double strand breaks as novel epigenetic actors: roles in cognition, health and neuro-inflammatory diseases | 2016 |
19 | FourFeFourS | Molecular Understanding of Generation and Trafficking of Mitochondrial [4Fe-4S] Clusters | 2015 |
20 | eADAM | Ultra-small electrochemical aptasensors for specific dopamine real-time monitoring | 2016 |
21 | Beta-splicenet | ALTERNATIVE SPLICING NETWORKS IN PANCREATIC BETA CELLS | 2015 |
22 | Re.B.Us | Rewiring Brain Units - bridging the gap of neuronal communication by means of intelligent hybrid systems | 2016 |
23 | Neuronal Trafficking | Mechanisms of synaptic growth and plasticity | 2016 |
24 | NeuroInCellNMR | In-cell NMR monitoring of alpha-Synuclein aggregation in neuronal cells | 2015 |
25 | MEMEMTUM | Neurological evaluation with simple tools to track evolution and perform early detection of neurodegenerative issues | 2015 |
26 | REGiREG | Regulating the immune regulators: targeting adaptive immune control | 2015 |
27 | ENVIROIMMUNE | Environmental modulators of the immune cell balance in health and disease | 2015 |
28 | YOUNGatHEART | YOUNGatHEART: CARDIAC REJUVENATION BY EPIGENETIC REMODELLING | 2015 |
29 | EMBRYOandLATERHEALTH | Embryonic origins of cardiovascular health in later life: disentangling early causal pathways in a lifecourse perspective | 2015 |
30 | MASSTRPLAN | MASS Spectrometry TRaining network for Protein Lipid adduct ANalysis | 2015 |
31 | SyDAD | Synaptic Dysfunction in Alzheimer Disease | 2015 |
32 | RobustSynapses | Maintaining synaptic function for a healthy brain: Membrane trafficking and autophagy in neurodegeneration | 2016 |
33 | Amygdala Circuits | Amygdala Circuits for Appetitive Conditioning | 2016 |
34 | SENTINEL | HIV-1 sensing and signaling in dendritic cells | 2015 |
35 | SEPCELL | Title of Proposal: Restoring the immune system homeostasis and organ function in severe community acquired pneumonia- induced sepsis through adipose derived allogeneic stem cells (SEPCELL Proje | 2015 |
36 | SENSOCOM | The tiny and the fast: the role of subcortical sensory structures in human communication | 2016 |
37 | rEnDOx | REDOX SIGNALING AND METABOLIC STATES IN ANGIOGENESIS IN HEALTH AND DISEASE | 2016 |
38 | Angiolnc | Endothelial long non-coding RNAs | 2016 |
39 | COSYN | Comorbidity and Synapse Biology in Clinically Overlapping Psychiatric Disorders | 2016 |
40 | MYOCURE | Development of an innovative gene therapy platform to cure rare hereditary muscle disorders | 2016 |
41 | SysMedPD | Systems Medicine of Mitochondrial Parkinson’s Disease | 2015 |
42 | NEUROVESSEL | Cell-cell interactions at the neurovascular interface | 2016 |
43 | SynaNet | Neurologic and Psychiatric Disorders: from synapses to networks | 2016 |
44 | GLION | Investigating glial glycogen utilization for ion homeostasis in the brain and its relevance to epileptogenesis: electrophysiology and pharmacology in awake behaving mice | 2016 |
45 | CaNANObinoids | From Peripheralized to Cell- and Organelle-Targeted Medicine: The 3rd Generation of Cannabinoid-1 Receptor Antagonists for the Treatment of Chronic Kidney Disease | 2016 |
46 | PSYCHOCELL | Cellular substrate of abnormal network maturation in neuropsychiatric disorders | 2016 |
47 | FORECAST | Fluorescence lifetime optical biopsy system | 2017 |
48 | RECORDER | Rare Earth based Upconversion Luminescent Nanomaterials as novel bioprobes for the detection of cardiac biomarkers | 2016 |
49 | ProstaPalp | Feasibility study to evaluate a novel prostate cancer diagnostic | 2016 |
50 | MITOCHONTACTS | Mitochondrial membrane contact sites | 2016 |
51 | SiCMetabol | Signaling Cascades in Metabolic Diseases | 2016 |
52 | NMDARETT | Cell-type Specific Mechanisms and Functional Consequences of Altered NMDA Receptor Development and Mecp2 Deficiency on Developing Cortical Circuits | 2016 |
53 | REGDAM | REGULATORY T CELLS AND TISSUE DAMAGE CONTROL | 2017 |
54 | SynapticMitochondria | Quality Control and Maintenance of Synaptic Mitochondria | 2016 |
55 | LocomotorIntegration | Functional connectome of brainstem circuits that control locomotion | 2016 |
56 | ParaplegiaAxonsER | Functional interactions between endoplasmic reticulum and mitochondria in Drosophila axons | 2017 |
57 | LYSOSOMICS | Functional Genomics of the Lysosome | 2016 |
58 | SYNDEGEN | Synaptic dysfunction in Neurodegenerative Diseases | 2017 |
59 | REMIX | Regulation of mitochondrial expression | 2016 |
60 | CohesinMolMech | Molecular mechanisms of cohesin-mediated sister chromatid cohesion and chromatin organization | 2016 |
61 | InterWiring | Wiring up the SomatoSensory Cortex | 2016 |
62 | uPROPHET | uPROPHET: Urinary PROteomics in Predicting HEart Transplantation outcomes | 2016 |
63 | ChromatinRemodelling | Single-Molecule And Structural Studies Of ATP-Dependent Chromatin Remodelling | 2017 |
64 | CholAminCo | Synergy and antagonism of cholinergic and dopaminergic systems in associative learning | 2017 |
65 | ALZSYN | Imaging synaptic contributors to dementia | 2016 |
66 | EXNADMINA | EXercise as a regulator of hepatic NAD metabolism and MItochondrial function in Non-Alcoholic fatty liver disease | 2016 |
67 | LysoMod | Genetic and Small Molecule Modifiers of Lysosomal Function | 2017 |
68 | MitoMethylome | Mitochondrial methylation and its role in health and disease | 2017 |
69 | NANOGLU | Enlightening synaptic architecture: nanoscale segregation of glutamate receptor subtypes | 2017 |
70 | mtFOIE GRAS | mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease | 2017 |
71 | BETA-BACT | Beta-cell inflammation and dysfunction induced by bacterial translocation | 2016 |
72 | DynamicBrainStates | Monitoring changes in brain states using dynamical causal networks | 2017 |
73 | TREATCilia | Novel Therapeutic Avenues for dynein-related Ciliopathies | 2017 |
74 | Mitomorphosis | Metabolic regulation of mitochondrial morphology | 2017 |
75 | EndoMitTalk | Endolysosomal-mitochondria crosstalk in cell and organism homeostasis | 2017 |
76 | ConCorND | Connectivity Correlate of Molecular Pathology in Neurodegeneration | 2017 |
77 | DENOCS | The Double Edged Role of Nitric Oxide and Hydrogen Peroxide in a Coral Symbiosis | 2017 |
78 | MitoDyaD | The role of the glucocorticoid receptor in dopaminoceptive neurons in mitochondrial dysfunction and vulnerability to depression | 2017 |
79 | EXO-EYE | Stem Cell-Derived Exosomes for the treatment of Traumatic and Degenerative Eye Disease | 2017 |
80 | MOBER | Maternal Obesity and Epigenetic Reprogramming: from Gametogenesis to Early Embryonic Development | 2017 |
81 | MOD-PROT | The role of tRNA processing and modifications in protein quality control. | 2018 |
82 | CALLIRHEO | Multi-scale computational hemodynamics in obese children and adolescents: enabling personalised prediction of cardiovascular disease | 2018 |
83 | PI3K-VAs | Activation of PI3K signalling in the pathogenesis of Vascular Anomalies | 2018 |
84 | funcSOFI-PD | Quantitative super-resolution optical fluctuation and phase microscopy for structural and functional imaging of Parkinson's disease | 2017 |
85 | IndiviStat | Individualizing statin therapy by using a systems pharmacology decision support algorithm | 2017 |
86 | MITODYN | Role of calcium fluxes in mitochondrial dynamics | 2017 |
87 | TANTUMorNEUVACCINE | Neutrophil subtypes: distinct cellular targets for therapeutic intervention | 2017 |
88 | BaskAtax | Modulation of Basket cell microcircuits in cerebellar cortex paroxysmal ataxia disorders | 2017 |
89 | EpiFAT | Epigenomic Reprogramming of Adipose Tissue Function and Energy Metabolism in Type 2 Diabetes | 2017 |
90 | StressPFCog | Mechanisms of stress-induced cognitive deficits : Role of the glucocorticoid receptor and its partners in the regulation of PFC function. | 2018 |
91 | iHEART | An Integrated Heart Model for the simulation of the cardiac function | 2017 |
92 | ImmuneCheckpointsAD | Immune checkpoint blockade for fighting Alzheimer’s disease | 2017 |
93 | NEMESIS | Neuron/mast cell interactions in skin diseases | 2017 |
94 | TelMetab | Telomere metabolism in Genome Stability and Disease | 2017 |
95 | Dam2Age | DNA Damage and Repair and its Impact on Healthy Ageing | 2017 |
96 | ESEMT | DETERMINING THE FUNCTIONAL CONSEQUENCES OF TRANSCRIPTIONAL ENHANCER ACTIVATION ON ALTERNATIVE SPLICING DURING EMT | 2017 |
97 | SynapseER | Endoplasmic reticulum structure and synaptic function in Drosophila | 2018 |
98 | CESYDE | Ceramide Synthases in Diabetic Beta Cell Demise | 2018 |
99 | CERDEV | Transcriptional controls over cerebellar neuron differentiation and circuit assembly | 2018 |
100 | MASTFAST | Rapid production of HUMAN MAST CELLS | 2017 |
101 | PREDESA | Non-invasive technology for remote screening and personalised therapy of sleeping disorders: EU piloting and commercialisation project | 2017 |
102 | EyeWideVision | An assessment and treatment tool for visual dysfunctions in children | 2017 |
103 | Brain2Bee | How dopamine affects social and motor ability - from the human brain to the honey bee | 2018 |
104 | ClearRing | An innovative, minimally invasive medical device used for treatment of Benign Prostatic Hyperplasia symptoms. | 2018 |
105 | HIV B Cell Function | Understanding HIV-specific B cell function and viral immunogenicity | 2018 |
106 | ACOUSTIC | Assessment of cardiac function by new ultrasound imaging strategies: towards a reliable clinical routine | 2018 |
107 | Alpha-Synuclein | Blocking the prion-like disease propagation in Parkinson’s disease and related disorders – model development and identification of cell-autonomous and cell non-autonomous factors. | 2019 |
108 | SEG | Anatomical and functional characterization of the neural circuits controlling ejaculation | 2019 |
109 | EnCAge | Progeria models to study endothelial cell ageing: implications for organ regeneration and fibrosis | 2020 |
110 | FODIAC | Foods for diabetes and cognition | 2018 |
111 | gaitDCODE | Decoding impairments of gait and balance from local field potentials in patients with Parkinson's disease. | 2018 |
112 | OSCBAGDIS | Oscillations in Basal Ganglia Disorders | 2018 |
113 | NACHO | Nicotine actions on beta cell function in health and disease | 2018 |
114 | STRIAVISE | How the striatum contributes to visual-selection | 2018 |
115 | EpiBarrier | Control of the blood-brain barrier integrity during seizures via the ATP-gated P2X7 receptor | 2018 |
116 | GlycoPCs | How do Pharmacological Chaperones work? Molecular basis of the actions of glycomimetics on keyglycosidases involved in lysosomal storage disorders | 2018 |
117 | OPVANOX-ARDS | Advanced pulmonary vascular monitoring for optimum Nitric Oxide delivery in acute respiratory distress syndrome. Expanding Nitric Oxide applications | 2018 |
118 | MITOPOMPE | Targeting mitochondrial defects and oxidative stress in Pompe Disease: from pathogenesis to therapy | 2019 |
119 | CORLID | Cortical markers of L-DOPA-induced dyskinesias | 2019 |
120 | AUTO NERVE | Tracers for targeting nerves in the autonomic nervous system | 2018 |
121 | MAPSYNE | Miniaturized automated patch-clamp system combined with high-density microelectrode arrays for multi-scale functional mapping of neuronal networks | 2018 |
122 | Huntingtin hPSC | Unraveling huntingtin function in cortical and striatal human development | 2018 |
123 | See-ACC | Cracking the Anterior Cingulate Code: Toward a Unified Theory of ACC Function | 2019 |
124 | EREDETIO | Wearable Device for Erectile Dysfunction Diagnostics and Treatment Monitoring | 2018 |
125 | KHON2bTREAT | Late Clinical Development of KH176: an innovative orphan drug to reach mitochondrial disease patients & market | 2018 |
126 | TriSol System | A heart valve prosthesis and delivery system intended to replace damaged tricuspid valves and prevent right ventricle dysfunction | 2018 |
127 | LOGIC LAB | Molecular logic lab-on-a-vesicle for intracellular diagnostics | 2018 |
128 | V.A. Cure | A multidisciplinary approach towards sustainable improvement in rare diseases care uniting Europe's top class vascular research to find new treatment strategies for vascular anomalies | 2019 |
129 | CICURE | Increasing complex I stability as a cure for mitochondrial diseases | 2018 |
130 | AIR-NB | Pre-natal exposure to urban AIR pollution and pre- and post-Natal Brain development | 2018 |
131 | FitteR-CATABOLIC | Survival of the Fittest: On how to enhance recovery from critical illness through learning from evolutionary conserved catabolic pathways | 2018 |
132 | MitoGuide | Integration and adaptation of impaired mitochondrial fitness in orchestrating T cell dysfunction in the tumor microenvironment | 2019 |
133 | INTERACT | Modelling the neuromusculoskeletal system across spatiotemporal scales for a new paradigm of human-machine motor interaction | 2019 |
134 | Neurovulnerability | Molecular mechanisms underlying selective neuronal death in motor neuron diseases | 2019 |
135 | SEPSCAV | SCAVENGING ON SEPSIS. DEVELOPMENT OF SEPSIS SPECIFIC DRUGS FROM HUMAN SCAVENGER RECEPTORS | 2019 |
136 | PREFERABLE | Project on Exercise for Fatigue Eradication in Advanced Breast cancer to improve quality of life | 2019 |
137 | BioDisOrder | Order and Disorder at the Surface of Biological Membranes. | 2019 |
138 | ReCoDE | Reshaping cortical circuits to decrease binge eating | 2019 |
139 | Centromere Stability | Mechanisms that maintain centromere DNA repeats stability in human cells. | 2020 |
140 | PD-MitoQUANT | PD-MitoQUANT – A quantitative approach towards the characterisation of mitochondrial dysfunction in Parkinson's disease | 2019 |
141 | Neu-i-Gut | Neural regulation of the immune system in the Gut | 2020 |
142 | LipTransProMet | The multi-omics role of lipid transfer proteins in lipid metabolism | 2019 |
143 | EPIOBESITY | Unravelling the hypothalamic epigenetic code behind obesity. | 2020 |
144 | Exh-Res-CART | Exhaustion-resistant CAR-T cells for the treatment of solid tumours | 2019 |
145 | NeuroStemX | In vitro model of Fragile X Syndrome using naïve iPSCs | 2019 |
146 | StopIG | Translating fundamental insights in podocyte metabolism and cell cycle regulation: development of a new treatment for Stopping crescentic Immune Glomerulonephritis | 2019 |
147 | HYMNS | Hypothalamic Modulation of Neocortical States | 2020 |
148 | MATRIX | Novel mitochondria-targeted therapies for cancer treatment-induced cardiotoxicity | 2019 |
149 | RememberEx | Human Subcortical-Cortical Circuit Dynamics for Remembering the Exceptional | 2019 |
150 | MitoQuant | Development of Deep-UV Quantitative Microscopy for the Study of Mitochondrial Dysfunction | 2019 |
151 | LinkFM | Linking Functional impact and Microstructural properties of fiber tract demyelination and remyelination in a rodent model of multiple sclerosis | 2019 |
152 | NG2-cells | The role of NG2 cells in the neural network in health and disease | 2019 |
153 | RTTOPHAGY | """Investigating autophagy enhancement as a therapeutic approach for the treatment of Rett syndrome.""" | 2019 |
154 | LIBSED | Libiguins: a remedy for the treatment of sexual dysfunctions | 2019 |
155 | HealthierWomen | A woman's reproductive experience: Long-term implications for chronic disease and death | 2019 |
156 | NEUMACS | Neuron-associated macrophages in the gut as novel target for the treatment of enteric neuropathies | 2019 |
157 | TeloRNAging | The role of damage-induced non coding RNA in the control of DNA damage response activation at telomeres in aging | 2019 |
158 | Dignum | Innovative toilet assistive device enabling people with reduced mobility to become independent | 2019 |
159 | ePANC-SPLICE | Regulation and Function of Endocrine-Specific Splicing Programs in Pancreas and their Role in Diabetes | 2020 |
160 | GenPercept | Spatio-temporal mechanisms of generative perception | 2019 |
161 | MECADISTEM | A new and innovative method to extract adipose Stromal Vascular Fraction: Application in post-prostatectomy erectile dysfunction | 2019 |
162 | variaTECT | A novel genetic assay for risk assessment of cognitive decline in Alzheimer’s Disease | 2019 |
163 | NextGen-O2k | Next Generation Instrument for In-Depth Analysis of Mitochondrial Fitness | 2019 |
164 | IMpaCT | Imaging life from Molecules to cells - building knowledge on Cryo-electron microscopy methodologies | 2019 |
165 | DiurnalHealth | The circadian clock in day-active species: preserving our health in modern society | 2019 |
166 | CAPTIS | An Embolic Protection Device for stroke prevention during heart valve replacement. | 2019 |
167 | FUELING-TRANSPORT | Deciphering the Role of Huntingtin in Energy Supply for Axonal Transport in Health and Huntington’s Disease | 2020 |
168 | NEUREKA | A smart, hybrid neural-computo device for drug discovery | 2019 |
169 | SweetBrain | A new perspective on the metabolic pathway to neuronal dysfunction: Using organs on a chip to elucidate the role of the brain microvasculature | 2020 |
170 | SynLink | Molecular Structure and Engineering of Synaptic Organizer Proteins in Health and Disease | 2020 |
171 | TheraLymph | Gene Therapy to restore lymphatic flow lymphedema | 2020 |
172 | Synthetic T-rEX | A synthetic biology approach for T cell exhaustion | 2020 |
173 | SIROCO | Sparing gene therapy for Inherited ROd COne dystrophies | 2019 |
174 | Gasgon | Development of a Novel Medical Device to Remove Air Bubbles from Medicines, Which Will Improve Patient Safety and Reduce Costs of IV Infusion | 2020 |
175 | AND-PD | COMORBIDITY MECHANISMS OF ANXIETY AND PARKINSON’S DISEASE | 2020 |
176 | ImmunoSep | Personalized immunotherapy in sepsis: a precision medicine based approach | 2020 |
177 | CLAUSTROFUNCT | Claustrum function in cortical processing and putative claustral dysfunction in schizophrenia | 2020 |
178 | NeuroTrans | NEUROtransmitter TRANSporters: from single molecules to human pathologies | 2020 |
179 | FatVirtualBiopsy | MRI toolkit for in vivo fat virtual biopsy | 2020 |
180 | HESSP | Hippocampus Extracellular Space Simulator Project (HESSP) | 2020 |
181 | ASTRA | ASsembly and phase Transitions of Ribonucleoprotein Aggregates in neurons: from physiology to pathology. | 2020 |
182 | UCUPA | Unraveling the Molecular Changes that Drive the Repression of the Unfolded Protein Response with Ageing | 2020 |
183 | symESTIM | Harnessing spinal electrical stimulation to modulate autonomic function after spinal cord injury | 2020 |
184 | Tac1-Ovulation | Addressing the Roles of Tachykinins in the Control of Ovulation: Focus on the Substance-P/Tachykinin Receptor Type 1 (Tac1/Tacr1) System | 2020 |
185 | ICaRMuSs | Intragranullar calcium regulation of mucin secretion and sorting. | 2020 |
186 | RENOPROTECT | Targeting tubular reabsorption for kidney protection | 2020 |
187 | LySyT | Understanding the role of lysosomes in the intercellular TNT-mediated spreading of α-synuclein and the impact of lysosomal dysfunction | 2020 |
188 | POMOLIM | Polycystic ovarian syndrome: novel molecular characterization and personalized in vitro maturation protocol. | 2020 |
189 | PATHOCODE | Molecular pathology of anti-viral T cell responses in the central nervous system | 2020 |
190 | NeuroVascOme | Gut microbiota-Neurovascular Interactions in Early Life | 2020 |
191 | Ctrl-BBB | Blood-brain barrier: from molecular mechanisms to intervention strategies | 2020 |