Explore the words cloud of the NEUcrest project. It provides you a very rough idea of what is the project "NEUcrest" about.
The following table provides information about the project.
Coordinator |
INSTITUT CURIE
Organization address contact info |
Coordinator Country | France [FR] |
Total cost | 4˙156˙404 € |
EC max contribution | 4˙156˙404 € (100%) |
Programme |
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers) |
Code Call | H2020-MSCA-ITN-2019 |
Funding Scheme | MSCA-ITN-ETN |
Starting year | 2019 |
Duration (year-month-day) | from 2019-11-01 to 2023-10-31 |
Take a look of project's partnership.
# | ||||
---|---|---|---|---|
1 | INSTITUT CURIE | FR (PARIS) | coordinator | 549˙604.00 |
2 | UNIVERSITY OF EAST ANGLIA | UK (NORWICH) | participant | 606˙345.00 |
3 | NATIONAL UNIVERSITY OF IRELAND GALWAY | IE (Galway) | participant | 549˙368.00 |
4 | UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE | ES (ELCHE) | participant | 501˙809.00 |
5 | KING'S COLLEGE LONDON | UK (LONDON) | participant | 303˙172.00 |
6 | STEMCELL TECHNOLOGIES UK LTD | UK (CAMBRIDGE) | participant | 303˙172.00 |
7 | AZELEAD | FR (MONTPELLIER) | participant | 274˙802.00 |
8 | IMAGINE INSTITUT DES MALADIES GENETIQUES NECKER ENFANTS MALADES FONDATION | FR (PARIS 15) | participant | 274˙802.00 |
9 | ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM | NL (ROTTERDAM) | participant | 265˙619.00 |
10 | MEDIZINISCHE UNIVERSITAET WIEN | AT (WIEN) | participant | 264˙207.00 |
11 | TEL AVIV UNIVERSITY | IL (TEL AVIV) | participant | 263˙500.00 |
Neurocristopathies caused by defects in the neural crest (NC) encompass a broad group of diseases from birth defects (cleftvpalate) to complex syndromes affecting systems such as heart, gut and adrenals. Because NC derivatives are diverse, mutations affecting this lineage can lead to pleiotropic phenotypes making it difficult to understand the causative events. Furthermore, NC-derived cancers, (e.g. melanoma and neuroblastoma) reactivate embryonic programs during tumour initiation. Our aim is to create a unique interdisciplinary network of scientists and clinicians partners from academia, healthcare, industry and the public sector with experience in gene discovery, genetics, functional studies and in vivo phenotyping aimed at training creative and innovative ESRs to study the overall genetic, molecular and environmental regulation of NC tissue in human health. To study each of complex aspects of NC and tumour formation, NEUcrest provides a synergistic framework for comprehensive analysis of candidate genes and biological processes, from patients to model systems to pharma and back to the clinic. With the aim to develop a unified strategy to identify new genetic and environmental factors that contribute to disease and to develop new drug targets for therapeutics, ESRs will address following scientific challenges: undertake novel gene discovery approaches; establish cellular/animal models of disease; establish integrative strategies for understanding neurocristopathies; optimise computational modelling of NC gene networks; establish translational strategies for drug screening in NC-related diseases; improve clinical management strategies of NC-disease and interface with patients and the public. Our training program takes into account training through research as well as multidisciplinary partnerships and networking opportunities. All together, this will improve our understanding of the fundamentals of neurocristopathy and contribute to improvements in healthcare.
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The information about "NEUCREST" are provided by the European Opendata Portal: CORDIS opendata.