The page lists 146 projects related to the topic "lineage".
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1 | CIRCODE | Cell-type specific mechanisms regulating rhythms in leukocyte homing | 2015 |
2 | CRCStemCellDynamics | Molecular Subtype Specific Stem Cell Dynamics in Developing and Established Colorectal Cancers | 2015 |
3 | TheLiRep | Exploring the Potential for Therapeutic Lineage Reprogramming of Diabetes | 2015 |
4 | LYMPHORG | Organ-specific mechanisms of lymphatic vascular development and specialisation | 2015 |
5 | CancerHetero | Dissection of tumor heterogeneity in vivo | 2015 |
6 | EpiNKT | Transcriptional and epigenetic control of innate-like T lymphocyte development | 2015 |
7 | BioMASCE | Biophysical Manipulation of Adult Stem Cell Epigenetics (BioMASCE) By Cell-Penetrating Nanoneedle Substrates | 2016 |
8 | CheliceLand | Molecular palaeobiology and comparative genomics of chelicerate terrestrialisation | 2015 |
9 | HGSOC | A novel approach into modeling origin and development of ovarian cancer | 2015 |
10 | Subpopulations | Investigating Fibrotic and Regenerative Fibroblast Populations in Muscular Dystrophy | 2016 |
11 | Tbet ILC JFN | The role of innate lymphoid cells in regulating intestinal inflammation | 2015 |
12 | MDR Tuberculosis | Evolution and success of the multi-drug resistant M. tuberculosis SIT41 (LAM7-TUR) lineage | 2015 |
13 | PGEPP | Are there rules to the game? Patterns of Genome Evolution in Paleopolyploid Plants | 2015 |
14 | PIOMES | Pbx proteins as pioneer factors promoting signal specificity in mesodermal differentiation | 2015 |
15 | ID4 | Role of Id4 in the adult subventricular zone of normal and injured brain | 2015 |
16 | EPIGENHEART | Epigenetic control of retinoic acid-dependent genes during heart development | 2015 |
17 | ZF-MEL-CHEMBIO | Chemical Biology in Zebrafish: Drug-Leads and New Targets in the Melanocyte Lineage and Melanoma | 2015 |
18 | TEC_Pro | Molecular control of self-renewal and lineage specification in thymic epithelial cell progenitors in vivo. | 2015 |
19 | RENOIR | RENal prOgenItoRs as tools to understand kidney pathophysiology and treat kidney disorders | 2015 |
20 | BRAINSTRUCT | Building up a brain: understanding how neural stem cell fate and regulation controls nervous tissue architecture | 2015 |
21 | STEMMING-FROM-NERVE | Targeted Cell Recruitment During Organogenesis And Regeneration: Glia Makes The Tooth | 2015 |
22 | SPICE | Synthetic Lethal Phenotype Identification through Cancer Evolution Analysis | 2015 |
23 | LineageDiscovery | Laying the Biological, Computational and Architectural Foundations for Human Cell Lineage Discovery | 2015 |
24 | Tendon Therapy Train | Engineering in vitro microenvironments for translation of cell-based therapies for tendon repair | 2016 |
25 | eMicrobevol | Early Microbial Evolution | 2015 |
26 | CELLPLASTICITY | New Frontiers in Cellular Reprogramming: Exploiting Cellular Plasticity | 2015 |
27 | EPIROSE | Self-Organising Capacity of Stem Cells during Implantation and Early Post-implantation Development: Implications for Human Development | 2016 |
28 | ZF-BrainReg | Regeneration of the adult zebrafish brain | 2016 |
29 | ZF_Blood | Less is more: Single Cell Analysis of Zebrafish Blood Development | 2016 |
30 | TEMPO | Terrestrial vertebrates and the evolutionary origins of morphological diversity | 2016 |
31 | EpiID | Single-cell epigenomics: quantifying epigenetic changes in individual cells using DamID | 2016 |
32 | PolyDomFormFuncReg | Discovering how polycomb domains form and function in gene regulation | 2016 |
33 | THE VERBAL APE | The primate precursors of human consonants and vowels | 2017 |
34 | PACE | Paleogenetic extraction and analysis from challenging environments | 2016 |
35 | INTEGRISTEM | Functions of Integrins in Mammary Stem Cell Activity and Tumorigenesis | 2016 |
36 | MPSC | Membrane Potential and Stem Cell Potency in Normal and Malignant Tissues | 2016 |
37 | MAIT | Evolutionary conserved T cells specific for a microbial metabolite: deciphering their development in the thymus and mapping their interactions with the gut microbiota in vivo. | 2016 |
38 | MIR-CHROM-C | Investigating the microRNA-chromatin remodelling circuitry in cardiac development | 2016 |
39 | Niche Fibrosis | Identification of regulatory signals from vascular niche in alveolar regeneration and pulmonary fibrosis | 2016 |
40 | DiseaseRecognition | Selection to outsmart the germs: The evolution of disease recognition and social cognition | 2017 |
41 | Antibodyomics | Vaccine profiling and immunodiagnostic discovery by high-throughput antibody repertoire analysis | 2016 |
42 | SOS Jelly | An advanced biological remedy against jellyfish stings | 2016 |
43 | Gap2bridge | Bridging the gap: an evolutionary genomics approach to illuminate the prokaryote-to-eukaryote transition. | 2017 |
44 | PLEIO-RANK | Pleiotropic treatment of cancer: RANK inhibitors targeting cancer stem cells and immunity | 2016 |
45 | MEDICI | The inflammatory gene expression program in macrophages: An integrative approach for the systematic characterization of transcriptional co-regulators | 2016 |
46 | TACKLE | TACK Superphylum and Lokiarchaeota Evolution: Dissecting the Ecology and Evolution of Archaea to Elucidate the Prokaryote to Eukaryote Transition | 2016 |
47 | DanioPattern | Development and Evolution of Colour Patterns in Danio species | 2016 |
48 | reLIVE | Unraveling complex organ regeneration through live imaging and molecular profiling approaches | 2017 |
49 | FatemapB | High Resolution Mapping of Fetal and Adult B Cell Fates During Ontogeny | 2017 |
50 | ResidentMacroPhage | Development, maintenance and functions of Resident Macrophages. | 2016 |
51 | EVALVE | Biomechanics and signaling in models of congenital heart valve defects | 2016 |
52 | RAPID | Chromatin dynamics resolved by rapid protein labeling and bioorthogonal capture | 2017 |
53 | SPACEVAR | Quantitative analysis of variability and robustness in spatial pattern formation | 2017 |
54 | GENECLOCKS | Reconstructing a dated tree of life using phylogenetic incongruence | 2017 |
55 | MUP-Trans-Zagros | Tracking the Middle to Upper Palaeolithic transition in the Kermanshah Valley, West Central Zagros Mountains, Iran. | 2016 |
56 | MetResistance | The role of tumour microenvironment in metastatic hormone-refractory prostate cancer | 2017 |
57 | STONECULT | Do early stone tools indicate a hominin ability to accumulate culture? | 2017 |
58 | BRECASTEM | Functional and Molecular Characterisation of Breast Cancer Stem Cells | 2017 |
59 | MultiLevelLandscape | Multilevel Selection for Specificity and Divergence in Bacteria | 2017 |
60 | Repro_organoid | Direct reprogramming of human astrocytes into functional neurons in cerebral organoids derived from genome edited hiPSCs | 2017 |
61 | EVOSPARROW | The evolutionary origins and consequences of human-commensalism in Passer sparrows | 2018 |
62 | MSCFate | Fate of mammary stem cells during tumorigenesis and clinical implications | 2017 |
63 | DevoSignGammaDelta | Tracking γδ T cell development and TCRγδ proximal signalling | 2018 |
64 | IDRE | IMPACT OF DNA REPLICATION ON EPIGENETICS | 2017 |
65 | BIOSTASIS | BIOlogical SignaTures of AnhydrobioSIS via comparative transcriptomics on different evolutionary lineages within tardigrades | 2018 |
66 | INSPirAUTOR | Understanding how Inositol Polyphosphates regulate autophagy and lipid body formation in photosynthetic organisms: crosstalk with TOR signaling. | 2018 |
67 | ECtomics | Dissecting spinal cord ependymal cell heterogeneity by single-cell transcriptomics | 2017 |
68 | MeGa | DNA Methylation dynamics during Gastrulation | 2018 |
69 | Fluidblasto | Luminal pressure: a sculptor for mouse blastocyst self-organisation | 2018 |
70 | NATRICINE | Phenotypic and lineage diversification of natricine snakes | 2017 |
71 | HemTree2.0 | Single cell genomic analysis and perturbations of hematopoietic progenitors: Towards a refined model of hematopoiesis | 2017 |
72 | INTUMORX | Elucidation of intratumoral heterogeneity in Kras-driven cancers | 2017 |
73 | EVOSOM | Evolution of multicellularity and somatic cell specialization | 2017 |
74 | BARCODED-CELLTRACING | Endogenous barcoding for in vivo fate mapping of lineage development in the blood and immune system | 2017 |
75 | ETAP | Tracing Evolution of Auxin Transport and Polarity in Plants | 2018 |
76 | SelforganisingEmbryo | Self-organisation across the scales in early mammalian development | 2017 |
77 | CellKarma | Dissecting the regulatory logic of cell fate reprogramming through integrative and single cell genomics | 2018 |
78 | IntScOmics | A single-cell genomics approach integrating gene expression, lineage, and physical interactions | 2018 |
79 | CRISS | CRISPR Gene Correction for Severe Combined Immunodeficiency Caused by Mutations in Recombination-activating gene 1 and 2 (RAG1 and RAG2) | 2017 |
80 | LinPro | Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development | 2017 |
81 | TERRESTREVOL | Exploring terra incognita: terrestrialization of arthropods in the era of genomics | 2018 |
82 | MicroBar | Microsatellite Barcoding: reconstructing the family tree of hematopoietic cells | 2018 |
83 | CENEVO | A new paradigm for centromere biology:Evolution and mechanism of CenH3-independent chromosome segregation in holocentric insects | 2018 |
84 | ORGANOMICS | Reconstructing human cortex development and malformation with single-cell transcriptomics | 2018 |
85 | StemCellHabitat | Metabolic and Timed Control of Stem Cell Fate in the Developing Animal | 2018 |
86 | DARE | Delivering Agile Research Excellence on European e-Infrastructures | 2018 |
87 | REBUILDCNS | Redirecting glial progenitor fate to rebuild the injured Brain | 2018 |
88 | CHROMREP | An integrative approach linking chromosomal evolution and biodiversity in reptiles from Madagascar | 2018 |
89 | PhenoSwitch | Phenotype switching: plasticity and/or differentiation of stromal cells and their progenitors within the tumour microenvironment regulate tumour fate. | 2018 |
90 | Reprogram-Diabetes | In vivo drug discovery for cellular reprogramming to β-cells – towards a future regenerative therapy for diabetes | 2018 |
91 | REPROGRAMIT | Control of T cell differentiation and plasticity through mitochondrial reprogramming | 2019 |
92 | GAP | Global dynamics of mountain diversification and persistence | 2019 |
93 | OESOPHAGEAL FATE | Epithelial/Mesenchymal Cross-talk in response to injury and early tumorigenesis; a spatiotemporal perspective | 2019 |
94 | InTheMLLrBALL | Innovative Therapeutic Strategies for Mixed Lineage Leukemia-rearranged B-cell Acute Lymphoblastic Leukemia | 2018 |
95 | SYMOBLIGA | Comparative genomics of host-symbiont dependency | 2018 |
96 | FIBROSIS | Fibroproliferative Invasive Fibroblasts in Idiopathic Pulmonary Fibrosis | 2018 |
97 | MiniBRAIN | Investigating the pathogenic mechanisms underlying TUBB2B-related brain malformations using induced pluripotent stem cells and cerebral organoids. | 2019 |
98 | DCPOIESIS | Steady-state and demand-driven dendritic cell generation | 2018 |
99 | SOLO | Single cell omics of the Oligodendrocyte Lineage in develOpment and disease | 2018 |
100 | PROTECTA | Pathogen-informed Resistance to Oomycete diseases in Ecosystems, Agriculture and Aquaculture | 2018 |
101 | IT4B-ALL | Therapeutic immunotherapy targeting NG2 and CD22 antigens for MLL-rearranged and MLL-germline B-cell Acute Lymphoblastic Leukemia | 2019 |
102 | BIOCARD | Deep BIOmodeling of human CARDiogenesis | 2018 |
103 | PROVEC | Promoting Osteogenesis through Vascular Endothelial Cells | 2019 |
104 | GIDE | Molecular diversification of inhibitory neurons during development | 2019 |
105 | MORPHEUS | Deciphering Bacteria-induced Morphogenesis and Protection in marine Eukaryotes | 2019 |
106 | TURNTAKING | Taking turns: The ‘missing’ link in language evolution? | 2019 |
107 | evolSingleCellGRN | Constraint, Adaptation, and Heterogeneity: Genomic and single-cell approaches to understanding the evolution of developmental gene regulatory networks | 2019 |
108 | ARCHEIS | Understanding the onset and impact of Aquatic Resource Consumption in Human Evolution using novel Isotopic tracerS | 2019 |
109 | CORKtheCAMBIA | Thickening of plant organs by nested stem cells | 2019 |
110 | NewHuman | Pathways to humanity: Adaptive niche diversity at the origins of the human lineage | 2019 |
111 | iDAPT | iDAPT: ice Dependent Adaptations for Plant Terrestrialization | 2020 |
112 | INHuMAN | Intra-tumoral heterogeneity in NRAS-driven metastatic melanoma | 2019 |
113 | SyLeNCe | Synapses between Leukaemia and its Neighbouring Cells | 2020 |
114 | CrossLingference | Cross-Linguistic statistical inference using hierarchical Bayesian models | 2019 |
115 | MutANTs | Mutation rate evolution in attine ants | 2020 |
116 | SingleCellAI | Deep-learning models of CRISPR-engineered cells define a rulebook of cellular transdifferentiation | 2019 |
117 | AmnioticID | Understanding the identity of the amniotic fluid stem cells | 2019 |
118 | BRAIN-MATCH | Matching CNS Lineage Maps with Molecular Brain Tumor Portraits for Translational Exploitation | 2019 |
119 | ReproXimera | Modelling in vivo lineage reprogramming of human astrocytes into induced neurons in the adult mouse brain | 2020 |
120 | QuiescStemGBM | Studying the role of Quiescent Cancer Stem Cells in GBM development using a novel in vivo cell cycle-based approach | 2020 |
121 | ANTHROPOID | Great ape organoids to reconstruct uniquely human development | 2019 |
122 | mAMBo | The role of ASCL1 and MYCN in human brain development | 2019 |
123 | EPICAN | Inhibiting tumor cell plasticity by targeting the epigenome in breast cancer | 2020 |
124 | EVER | Evolution of VEnom Regulation | 2019 |
125 | MADMpancreas | Using the precision mouse genetic tool MADM to elucidate the role of EGFR in directing beta cell differentiation and pancreatic morphogenesis | 2019 |
126 | Healthybiota | Microbiota-host interactions for integrative metabolic health reprogramming | 2019 |
127 | ROAR | Role of endocycle in Acute Kidney Injury Response and Chronic Kidney Disease development | 2019 |
128 | MS | Unravelling the molecular and cellular mechanism of metastasis | 2020 |
129 | NEUcrest | Training European Experts in Multiscale Studies of Neural Crest Development and Disorders: from Patient to Model Systems and Back again. | 2019 |
130 | CellularBiographies | Global views of cell type specification and differentiation | 2020 |
131 | TerreStriAL | Terrestrialization: Stress Signalling Dynamics in the Algal Progenitors of Land Plants | 2019 |
132 | DyNAmecs | Early embryonic events, life-long consequences: DNA methylation dynamics in mammalian development | 2020 |
133 | ANIMATE | Adaptive Immunity in Human Atherosclerosis: Understanding its Cellular Basis to Define Novel Immunomodulatory Therapies | 2020 |
134 | PLASTINET | Plasticity of the Pluripotency Network | 2020 |
135 | RhabdoEvo | Deciphering the cellular origin and evolution of malignant rhabdoid tumors | 2019 |
136 | EVOMENS | The evolution of menstruation in primates | 2020 |
137 | DYNOME | Barcoding gene expression dynamics at single-molecule resolution | 2020 |
138 | HumanPlacenta | Human Placental Development and the Uterine Microenvironment | 2020 |
139 | ALTER-brain | Metastasis-associated altered molecular patterns in the brain | 2020 |
140 | OLI.VAS | The Oligo-Vascular interface: understanding its properties and functions | 2020 |
141 | EXPLOSIA | EXpansion and Phenotype Loss Of SMCs In Atherosclerosis: Causal effects and therapeutic possibilities | 2020 |
142 | NEANDER-TALe | Origins and Evolution of the Neanderthal Cranial Morphology | 2021 |
143 | ChRONAM-H | Chromatin Regulation Of Normal And Malignant Haematopoiesis | 2020 |
144 | STAMPEDE | Spatial and Temporal Analysis of Modern and Past Elephant DivErsity | 2021 |
145 | SecondCANCERinKIDS | What causes therapy-related malignancies in childhood cancer survivors? Dissecting the etiology of second cancers | 2020 |
146 | EscaPI | Exploring the non-genetic (i.e. ePIgenetic) mechanisms that contribute to therapy Escape in melanoma | 2020 |