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STRICT SIGNED

SN: The first blood biomarker to accurately STratify mortality Risk In patients with Cardiac arrhyTmia

Total Cost €

EC-Contrib. €

Partnership

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STRICT project word cloud

Explore the words cloud of the STRICT project. It provides you a very rough idea of what is the project "STRICT" about.

25 globally blood expertise cardioverter vitro defibrillator death recruit linked least patients arrhythmias house victims sudden unknowingly levels physical regime activated overtreatment ecg lvef arrythmia exams advantage eligible biomedical secretoneurin patented device maturation global diagnosis mortality ejection associate diagnostic 20k cardiac icds cardinor trl8 shown left 3b positioning ventricle lt burden cvd patient lives 35 never 51 stratify status survival health ivd sme caused implantable risk accurate worldwide 67 disease data pinpoint innovation cardiologists icd normal boost sn quality surgery difficult killer assurance alone echocardiogram skills company correlation decision biomarker coming acquiring ask detect reducing competitive saving biomarkers ventricular market cardiovascular scd

Project "STRICT" data sheet

The following table provides information about the project.

Coordinator	CARDINOR AS Organization address address: GAUSTADALLEEN 21 city: OSLO postcode: 349 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Norway [NO]
Total cost	119˙805 €
EC max contribution	119˙805 € (100%)
Programme	1. H2020-EU.2.3.2.2. (Enhancing the innovation capacity of SMEs)
Code Call	H2020-INNOSUP-2019-02
Funding Scheme	CSA
Starting year	2019
Duration (year-month-day)	from 2019-12-15 to 2020-12-14

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	CARDINOR AS CARDINOR AS Organization address address: GAUSTADALLEEN 21 city: OSLO postcode: 349 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (OSLO)	coordinator	119˙805.00

Map

Project objective

Cardiovascular disease (CVD) is the no. 1 killer worldwide. 25% of all CVD mortality is caused by ventricular arrhythmias that lead to sudden cardiac death (SCD). The diagnosis of arrhythmias is difficult but crucial for accurate decision-making and patient survival. To assess the patient’s status, cardiologists currently ask: physical exams, some cardiac biomarkers data, an ECG (which may detect an arrythmia) and an echocardiogram to measure the blood ejection from the left ventricle (LVEF), since there is a correlation between LVEF and risk of ventricular arrhythmias. If LVEF is < 35%, the patient is eligible for implantable cardioverter-defibrillator (ICD) surgery, which costs at least 20K€. Still, around 51 % of victims of SCD have normal LVEF. In addition, 67% of all implemented ICDs are never activated because those patients were (unknowingly) at low-risk for arrhythmias, which represents a 1.3B€ overtreatment cost / year in the EU alone. CardiNor is bringing to market a new in vitro diagnostic (IVD) test to measure blood levels of Secretoneurin (SN), a globally patented biomarker and the only one shown to be specifically linked to ventricular arrhythmias. With SN data, cardiologists will be able to stratify patients according to their risk as well as to pinpoint high-risk patients not identified by the current diagnostic regime, thus reducing health burden costs and saving lives. CardiNor needs the SME Innovation Associate Programme to boost R&D activities within test maturation and effectively take it to TRL8. Currently, we do not have in-house expertise in biomedical device development or quality assurance. Therefore, we are looking to recruit an Innovation Associate. Acquiring these skills is important for CardiNor to maintain competitive advantage over coming years, positioning our company to high growth in the global CVD biomarkers market.

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The information about "STRICT" are provided by the European Opendata Portal: CORDIS opendata.