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AVANT SIGNED

Alternatives to Veterinary ANTimicrobials

Total Cost €

0

EC-Contrib. €

0

Partnership

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 AVANT project word cloud

Explore the words cloud of the AVANT project. It provides you a very rough idea of what is the project "AVANT" about.

threat    diseases    2030    dosage    stimulating    limited    projected    farmer    gut    piglets    negative    mode    polymers    indication    consumption    health    survey    diarrhoea    colistin    pork    additive    optimized    actor    medicinal    tested    stabilizing    consumers    probiotic    welfare    avant    options    regulatory    antimicrobial    toxicity    strategies    zinc    period    mathematical    perception    feed    sectorial    bacteriophages    interventions    choices    prevention    veterinarian    immuno    microbiota    transplantation    transmission    portfolio    treatment    considerations    pig    antimicrobials    resistance    coli    respiratory    public    pigs    efficacy    humans    estimate    economic    veterinary    feeding    bacterial    demographics    trials    sows    alternative    restrictions    infections    symbiotic    animal    risk    containing    zoonotic    data    assessing    advice    farm    livestock    formulation    alternatives    post    inter    market    select    action    quick    injectable    weaning    faecal    variety    clinical    entry    enterotoxigenic   

Project "AVANT" data sheet

The following table provides information about the project.

Coordinator
KOBENHAVNS UNIVERSITET 

Organization address
address: NORREGADE 10
city: KOBENHAVN
postcode: 1165
website: www.ku.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 6˙537˙033 €
 EC max contribution 5˙999˙905 € (92%)
 Programme 1. H2020-EU.3.2.1.1. (Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience)
 Code Call H2020-SFS-2019-1
 Funding Scheme IA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2024-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 2˙254˙125.00
2    THE ROYAL VETERINARY COLLEGE UK (LONDON) participant 586˙756.00
3    SCHOTHORST FEED RESEARCH B.V. NL (LELYSTAD) participant 548˙121.00
4    UNIVERSIDAD COMPLUTENSE DE MADRID ES (MADRID) participant 515˙000.00
5    STICHTING WAGENINGEN RESEARCH NL (WAGENINGEN) participant 393˙931.00
6    RTDS - VEREIN ZUR FORDERUNG DER KOMMUNIKATION UND VERMITTLUNG VON FORSCHUNG, TECHNOLOGIE UND INNOVATION (RTDS VEREIN, ENGL. RTDS ASSOCIATION) AT (WIEN) participant 357˙791.00
7    LANDBRUG & FODEVARER F.M.B.A. DK (KOBENHAVN V) participant 282˙541.00
8    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) participant 260˙420.00
9    KLIFOVET AG DE (MUNCHEN) participant 260˙181.00
10    COOPERL INNOVATION S.A.S FR (LAMBALLE) participant 240˙316.00
11    BIOMIN HOLDING GMBH AT (GETZERSDORF BEI TRAISMAUER) participant 123˙333.00
12    FEDERATION OF VETERINARIANS OF EUROPE AISBL BE (BRUXELLES) participant 96˙041.00
13    LABORATORIOS OVEJERO SA ES (LEON) participant 49˙364.00
14    EASY-AGRICARE AS DK (NYKOBING) participant 31˙981.00

Map

 Project objective

Antimicrobial resistance in livestock is a public health threat due to the risk of zoonotic transmission to humans and its negative consequences on animal health and welfare when diseases cannot be treated. AVANT is a multi-actor inter-sectorial project aimed at developing alternatives to antimicrobials for the management of bacterial infections in pigs, especially diarrhoea during the weaning period, as the major indication for antimicrobial use in livestock in Europe. Antimicrobial treatment options for pigs are increasingly limited because of planned restrictions in the use of colistin and zinc, two current choices for treatment of post-weaning diarrhoea. The AVANT portfolio comprises a variety of alternatives for treatment or prevention of diarrhoea and/or respiratory infections, namely (i) gut-stabilizing interventions based on a symbiotic (pre- and probiotic) product and faecal microbiota transplantation; (ii) novel veterinary medicinal products containing bacteriophages and polymers for targeted treatment of enterotoxigenic E.coli infections; (iii) immuno-stimulating injectable and feed additive products, and (iv) alternative feeding strategies targeting sows and piglets. During pre-clinical studies, efficacy, toxicity, and mode of action of these interventions is tested, and their dosage and formulation optimized. The results and a survey for veterinarian-, farmer- and consumers perception of antimicrobial alternatives, will be used together with legal and economic considerations to select three interventions for large-scale farm trials, assessing clinical efficacy and impact on antimicrobial use. All steps are supported by regulatory advice for quick market entry post-project. Generated and existing data on antimicrobial use, pig demographics and projected consumption of pork, will be used in mathematical modelling to estimate the reduction in antimicrobial use that could be achieved by 2030 if the AVANT alternatives were widely adopted in pig production.

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The information about "AVANT" are provided by the European Opendata Portal: CORDIS opendata.

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