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STI-001 SIGNED

Turn Cancer Immunotherapy Effective in Most Patients

Total Cost €

0

EC-Contrib. €

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Partnership

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 STI-001 project word cloud

Explore the words cloud of the STI-001 project. It provides you a very rough idea of what is the project "STI-001" about.

anti    strategy    cancer    inhibitors    ligand    validate    first    kill    company    leader    tumour    biological    competitors    virus    feasibility    metastatic    edge    cells    shown    restores    disruptive    activate    worldwide    survival    demonstrated    regulatory    beginning    innate    weaker    plan    answer    sti    named    letters    proprietary    larger    physicians    vlps    licensing    safe    immuno    see    distant    public    2m    weakened    001    sting    drugs    develops    smei1    stimulatory    create    inducing    encapsulates    genes    option    unresponsive    private    intent    cancers    pharmaceutical    date    stimulator    immune    pipeline    tumor    confirm    tumours    therapeutic    manufacturing    showed    million    potent    particle    update    marketing    50    vlp    ligands    nevertheless    raised    natural    fto    business    interferon    restore    chemical    durable    patients    rates    immunotherapy    fires    stimunity    unseen    companies    cutting    checkpoint   

Project "STI-001" data sheet

The following table provides information about the project.

Coordinator		 STIMUNITY SAS 

Organization address
address: RUE D'AMSTERDAM 57
city: PARIS
postcode: 75008
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country France [FR]
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-12-01   to  2020-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STIMUNITY SAS FR (PARIS) coordinator 50˙000.00

Map

 Project objective

Stimunity is a company that develops disruptive immuno-stimulatory biological drugs to restore the immune system against tumor cells. Immune checkpoint inhibitors showed great potential in cancer immunotherapy after achieving 5-year survival rates for patients with advanced or metastatic cancers, unseen by physicians before. This is a promising beginning. Nevertheless, 5 million patients worldwide remain unresponsive to immunotherapy and do not have any other therapeutic option. On average it represents 50% of all cancers. A promising answer to this problem is the development of new drugs that activate the STING (STimulator of INterferon Genes) pathway, which fires up the innate immune system of these unresponsive patients, inducing a potent and durable anti-tumour immune response. It is expected to be effective on a much larger number of cancer patients. Stimunity’s first product, named STI-001, restores weakened immune systems to kill tumour cells. It is especially effective on distant tumours. Competitors using chemical STING ligands have shown a much weaker immune response than STI-001. STI-001 is based on a safe cutting-edge Virus-Like Particle (VLP) technology that encapsulates the best-known natural STING ligand and efficiently deliver it into immune cells. There is high interest in STI-001, as demonstrated by public and private funding (raised €2.2M to date) and advanced discussions with major pharmaceutical companies (see Letters of Intent). SMEi1 project will allow Stimunity to i) confirm the technical feasibility of manufacturing STI-001, (ii) update the FTO, (iii) assess regulatory issues, (iv) validate the marketing and business plan. Our long-term goal is to develop a pipeline of products based on proprietary VLPs in cancer immunotherapy and create a long term out-licensing strategy as a worldwide leader in VLP-based immunotherapy.

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The information about "STI-001" are provided by the European Opendata Portal: CORDIS opendata.

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